Drug-induced loss of unstably amplified genes.
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[1] R T Schimke,et al. Gene amplification in cultured cells. , 1988, The Journal of biological chemistry.
[2] L. Bolund,et al. Characterization of a camptothecin-resistant human DNA topoisomerase I. , 1988, The Journal of biological chemistry.
[3] A. Pegg,et al. Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy. , 1988, Cancer research.
[4] R. Snapka,et al. Swiveling and decatenation of replicating simian virus 40 genomes in vivo , 1988, Molecular and cellular biology.
[5] Y. Suzuki,et al. Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[6] J. Endicott,et al. Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance , 1986, Nature.
[7] R. Snapka. Topoisomerase inhibitors can selectively interfere with different stages of simian virus 40 DNA replication. , 1986, Molecular and cellular biology.
[8] M. Schwab,et al. Oncogene amplification in tumor cells. , 1986, Advances in cancer research.
[9] R. Hertzberg,et al. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. , 1985, The Journal of biological chemistry.
[10] I. Pastan,et al. Amplification of DNA sequences in human multidrug-resistant KB carcinoma cells. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[11] P. Farnham,et al. Ultrastructural features of minute chromosomes in a methotrexate-resistant mouse 3T3 cell line. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[12] E. Moore,et al. The inhibition of ribonucleoside diphosphate reductase by hydroxyurea, guanazole and pyrazoloimidazole (IMPY). , 1985, Pharmacology & therapeutics.
[13] D. Housman,et al. Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells , 1984, Nature.
[14] V. Ling,et al. Co-amplification of double minute chromosomes, multiple drug resistance, and cell surface P-glycoprotein in DNA-mediated transformants of mouse cells , 1984, Molecular and cellular biology.
[15] J. Milbrandt,et al. DNA sequence amplification in mammalian cells. , 1984, International review of cytology.
[16] R. Snapka,et al. Loss of unstably amplified dihydrofolate reductase genes from mouse cells is greatly accelerated by hydroxyurea. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[17] A. Feinberg,et al. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. , 1983, Analytical biochemistry.
[18] T. Tlsty,et al. Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea , 1983, Molecular and cellular biology.
[19] E. Wintersberger,et al. Does hydroxyurea inhibit DNA replication in mouse cells by more than one mechanism? , 1983, Molecular and cellular biology.
[20] J. Cowell,et al. Double minutes and homogeneously staining regions: gene amplification in mammalian cells. , 1982, Annual review of genetics.
[21] M. Yamamoto,et al. Hydroxyurea inhibits degradation of internalized epidermal growth factor in HeLa cells. , 1982, Biochemical and biophysical research communications.
[22] D. Hooper,et al. Antagonism of the B subunit of DNA gyrase eliminates plasmids pBR322 and pMG110 from Escherichia coli , 1982, Journal of bacteriology.
[23] P. Barker. Double minutes in human tumor cells. , 1982, Cancer genetics and cytogenetics.
[24] R T Schimke,et al. Relationship of amplified dihydrofolate reductase genes to double minute chromosomes in unstably resistant mouse fibroblast cell lines , 1981, Molecular and cellular biology.
[25] D. W. Ross. Volume increase in L5222 leukemic cells following chemotherapy: manifestation of leukemic cell damage. , 1981, Leukemia research.
[26] R. Schimke,et al. Chromosomal and extrachromosomal localization of amplified dihydrofolate reductase genes in cultured mammalian cells. , 1981, Cold Spring Harbor symposia on quantitative biology.
[27] D. W. Ross. CELL VOLUME GROWTH AFTER CELL CYCLE BLOCK WITH CHEMOTHERAPEUTIC AGENTS , 1976, Cell and tissue kinetics.
[28] J. Ciak,et al. Elimination of Resistance Determinants from R-Factor R1 by Intercalative Compounds , 1976, Antimicrobial Agents and Chemotherapy.
[29] W. K. Sinclair. Hydroxyurea: effects on Chinese hamster cells grown in culture. , 1967, Cancer research.