Proinsulin radioimmunoassay in the evaluation of insulinomas and familial hyperproinsulinemia.

[1]  W. Duckworth,et al.  Receptor binding and biological potency of several split forms (conversion intermediates) of human proinsulin. Studies in cultured IM-9 lymphocytes and in vivo and in vitro in rats. , 1985, The Journal of biological chemistry.

[2]  S. Shoelson,et al.  Biochemical and clinical implications of proinsulin conversion intermediates. , 1985, The Journal of clinical investigation.

[3]  J. Conlon,et al.  Measurement of Circulating Human Proinsulin Concentrations Using a Proinsulin-specific Antiserum , 1985, Diabetes.

[4]  S. Shoelson,et al.  A Radioimmunoassay for Circulating Human Proinsulin , 1985, Diabetes.

[5]  P. Gruppuso,et al.  Familial hyperproinsulinemia due to a proposed defect in conversion of proinsulin to insulin. , 1984, The New England journal of medicine.

[6]  K. Polonsky,et al.  The metabolic effects of biosynthetic human proinsulin in individuals with type I diabetes. , 1984, The Journal of clinical endocrinology and metabolism.

[7]  S. Shoelson,et al.  Familial hyperproinsulinemia. Two cohorts secreting indistinguishable type II intermediates of proinsulin conversion. , 1984, The Journal of clinical investigation.

[8]  A. Kitabchi,et al.  A Rapid Means of Separating A14-125I-Insulin from Heterogeneously Labeled Insulin Molecules for Biologic Studies , 1982, Diabetes.

[9]  K. Polonsky,et al.  Evidence for the Presence of Somatostatin 28 in Plasma , 1982, Diabetes.

[10]  S. Berson,et al.  Evidence against extrapancreatic insulin synthesis. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[11]  J. Sosenko,et al.  Glycosylated Hemoglobins: Increased Glycosylation of Hemoglobin A in Diabetic Patients , 1979, Diabetes.

[12]  J. M. May,et al.  Characterization of proinsulin-insulin intermediates in human plasma. , 1978, The Journal of clinical investigation.

[13]  H. Kuzuya,et al.  Characterization of Seven C-peptide Antisera , 1978, Diabetes.

[14]  A. Rubenstein,et al.  31 – Insulin, Proinsulin, and C-Peptide , 1978 .

[15]  T. Merimee,et al.  Hypoglycemia in Man: Pathologic and Physiologic Variants , 1977, Diabetes.

[16]  C. Kahn,et al.  Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting. , 1976, The Journal of clinical investigation.

[17]  K. Gabbay,et al.  Familial hyperproinsulinemia. An autosomal dominant defect. , 1976, The New England journal of medicine.

[18]  M. J. Ursich,et al.  Acute- and Late-Phase Insulin Secretion and Glucose Tolerance in Mild Alloxan Diabetes in Dogs , 1976, Diabetes.

[19]  C. Kahn,et al.  Plasma proinsulin-like components. , 1974, Israel journal of medical sciences.

[20]  Substrate studies for insulin-specific protease. , 1973, European journal of biochemistry.

[21]  W. Duckworth,et al.  Effect of hydrocortisone and corticotropin on glucose-induced insulin and proinsulin secretion in man. , 1973, The Journal of clinical endocrinology and metabolism.

[22]  W. Duckworth,et al.  Direct measurement of plasma proinsulin in normal and diabetic subjects. , 1972, The American journal of medicine.

[23]  S. Fajans,et al.  Circulating proinsulin-like material in patients with functioning insulinomas. , 1971, The New England journal of medicine.

[24]  D. Steiner,et al.  Human serum proinsulin. , 1970, The Journal of clinical investigation.

[25]  S. Berson,et al.  Significance of Human Plasma Insulin Sephadex Fractions , 1969, Diabetes.

[26]  J. Roth,et al.  Plasma insulin: fluctuations in the "big" insulin component in man after glucose and other stimuli. , 1969, The Journal of clinical investigation.

[27]  A. Lazarow,et al.  Immunoassay of Insulin: Two Antibody System: Plasma Insulin Levels of Normal, Subdiabetic and Diabetic Rats , 1963, Diabetes.