论文信息 - Quantitative birefringence imaging of biological samples using quadri-wave interferometry

Quantitative birefringence imaging of biological samples using quadri-wave interferometry

We describe a new technique based on the use of a high-resolution quadri-wave lateral shearing interferometry wave front sensor to perform quantitative linear birefringence measurements on biological samples. The system combines quantitative phase images with different excitation polarizations to create birefringence images. This technique is fast and compatible with living samples. It gives information about the local retardance and structure of their anisotropic components.

[1] Serge Monneret,et al. Noniterative boundary-artifact-free wavefront reconstruction from its derivatives. , 2012, Applied optics.

[2] E D Salmon,et al. Birefringence of single and bundled microtubules. , 1998, Biophysical journal.

[3] T. Wilson,et al. Quantitative polarized light microscopy , 2003, Journal of microscopy.

[4] B. Wattellier,et al. Quadriwave lateral shearing interferometry for quantitative phase microscopy of living cells. , 2009, Optics express.

[5] In Hee Shin,et al. New, simple theory-based, accurate polarization microscope for birefringence imaging of biological cells. , 2010, Journal of biomedical optics.