The impact of non‐motor symptoms on health‐related quality of life of patients with Parkinson's disease

Non‐motor symptoms are detrimental to health‐related quality of life (HRQoL) of Parkinson's disease patients. In this study, the Non‐Motor Symptoms Scale (NMSS) was used to assess the impact of the non‐motor symptoms on HRQoL of Parkinson's disease patients.

[1]  P. Kind,et al.  The Influence of Ill-Health Experience on the Valuation of Health , 1998, PharmacoEconomics.

[2]  Pablo Martinez-Martin,et al.  Prevalence of nonmotor symptoms in Parkinson's disease in an international setting; Study using nonmotor symptoms questionnaire in 545 patients , 2007, Movement disorders : official journal of the Movement Disorder Society.

[3]  W. Weiner,et al.  Non-recognition of depression and other non-motor symptoms in Parkinson's disease. , 2002, Parkinsonism & related disorders.

[4]  J. Larsen,et al.  Influence of clinical and demographic variables on quality of life in patients with Parkinson’s disease , 1999, Journal of neurology, neurosurgery, and psychiatry.

[5]  K. Chaudhuri,et al.  The nondeclaration of nonmotor symptoms of Parkinson's disease to health care professionals: An international study using the nonmotor symptoms questionnaire , 2010, Movement disorders : official journal of the Movement Disorder Society.

[6]  A. Lees,et al.  A clinicopathologic study of 100 cases of Parkinson's disease. , 1993, Archives of neurology.

[7]  A M Stiggelbout,et al.  A short scale for the assessment of motor impairments and disabilities in Parkinson’s disease: the SPES/SCOPA , 2004, Journal of Neurology, Neurosurgery & Psychiatry.

[8]  Laurent Gerbaud,et al.  Impact of the motor complications of Parkinson's disease on the quality of life , 2005, Movement disorders : official journal of the Movement Disorder Society.

[9]  G. Polesello,et al.  Health-Related Quality of Life and sleep disorders in Parkinson’s disease , 2003, Neurological Sciences.

[10]  T. Babić,et al.  Association of rural life setting and poorer quality of life in Parkinson's disease patients: a cross‐sectional study in Croatia , 2007, European journal of neurology.

[11]  Marjan Jahanshahi,et al.  What contributes to quality of life in patients with Parkinson's disease? , 2000, Journal of neurology, neurosurgery, and psychiatry.

[12]  G. Naglie,et al.  Predictors of deterioration in health‐related quality of life in Parkinson's disease: Results from the DATATOP trial , 2008, Movement disorders : official journal of the Movement Disorder Society.

[13]  J. Larsen,et al.  Quality of life measurements in patients with Parkinson's disease: A community‐based study , 1998, European journal of neurology.

[14]  M. Hoehn,et al.  Parkinsonism , 1967, Neurology.

[15]  H. Bruschini,et al.  Voiding dysfunction in patients with Parkinson's disease: Impact of neurological impairment and clinical parameters , 2009, Neurourology and urodynamics.

[16]  M. Akbostancı,et al.  Assessment of sexual dysfunction in patients with Parkinson’s disease: a case–control study , 2008, European journal of neurology.

[17]  C. Tanner,et al.  Health related quality of life in early Parkinson's disease: impact of motor and non-motor symptoms, results from Chinese levodopa exposed cohort. , 2009, Parkinsonism & related disorders.

[18]  D. Grosset,et al.  Patient‐perceived involvement and satisfaction in Parkinson's disease: Effect on therapy decisions and quality of life , 2005, Movement disorders : official journal of the Movement Disorder Society.

[19]  Paolo Barone,et al.  The metric properties of a novel non‐motor symptoms scale for Parkinson's disease: Results from an international pilot study , 2007, Movement disorders : official journal of the Movement Disorder Society.

[20]  R. Fitzpatrick,et al.  The Parkinson's Disease Questionnaire (PDQ-39): development and validation of a Parkinson's disease summary index score. , 1997, Age and ageing.

[21]  A Forbes,et al.  A multicentre longitudinal observational study of changes in self reported health status in people with Parkinson’s disease left untreated at diagnosis , 2006, Journal of Neurology, Neurosurgery & Psychiatry.

[22]  M. Jahanshahi,et al.  Quality of life in Parkinson's disease: The relative importance of the symptoms , 2008, Movement disorders : official journal of the Movement Disorder Society.

[23]  W. Au,et al.  Factors affecting health‐related quality of life amongst Asian patients with Parkinson’s disease , 2008, European journal of neurology.

[24]  J. Benito-León,et al.  Impact of Fatigue in Parkinson’s Disease: The Fatigue Impact Scale for Daily Use (D-FIS) , 2006, Quality of Life Research.

[25]  R. Fimmers,et al.  Autonomic dysfunction in 3414 Parkinson's disease patients enrolled in the German Network on Parkinson's disease (KNP e.V.): the effect of ageing , 2007, European journal of neurology.

[26]  S. Das,et al.  Quality of life in Parkinson's disease--Indian scenario. , 2006, The Journal of the Association of Physicians of India.

[27]  I. Forgacs,et al.  Intrajejunal levodopa infusion in Parkinson's disease: A pilot multicenter study of effects on nonmotor symptoms and quality of life , 2009, Movement disorders : official journal of the Movement Disorder Society.

[28]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .

[29]  Angelo Antonini,et al.  The PRIAMO study: A multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease , 2009, Movement disorders : official journal of the Movement Disorder Society.

[30]  A. Lees,et al.  Nonmotor symptoms as presenting complaints in Parkinson's disease: A clinicopathological study , 2008, Movement disorders : official journal of the Movement Disorder Society.

[31]  A. Williams EuroQol : a new facility for the measurement of health-related quality of life , 1990 .

[32]  A M Stiggelbout,et al.  Patient-reported autonomic symptoms in Parkinson disease , 2007, Neurology.

[33]  K. Chaudhuri,et al.  Non-motor symptoms of Parkinson's disease: diagnosis and management , 2006, The Lancet Neurology.

[34]  Paolo Barone,et al.  International multicenter pilot study of the first comprehensive self‐completed nonmotor symptoms questionnaire for Parkinson's disease: The NMSQuest study , 2006, Movement disorders : official journal of the Movement Disorder Society.

[35]  A. Kasuya EuroQol--a new facility for the measurement of health-related quality of life. , 1990, Health policy.

[36]  Pablo Martínez-Martín,et al.  An introduction to the concept of “quality of life in Parkinson’s disease” , 1998, Journal of Neurology.

[37]  W. Gibb,et al.  The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. , 1988, Journal of neurology, neurosurgery, and psychiatry.

[38]  M Zappia,et al.  International study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson disease , 2009, Neurology.

[39]  J. Larsen,et al.  The influence of fatigue on health‐related quality of life in patients with Parkinson's disease , 2003, Acta neurologica Scandinavica.

[40]  R. Sakakibara,et al.  Questionnaire-based assessment of pelvic organ dysfunction in Parkinson's disease , 2001, Autonomic Neuroscience.

[41]  R M Werner,et al.  The EQ-5D—a generic quality of life measure—is a useful instrument to measure quality of life in patients with Parkinson's disease , 2001, Journal of neurology, neurosurgery, and psychiatry.