Nanoprobes for biomedical imaging in living systems

[1]  Eun Seong Lee,et al.  A charge-switched nano-sized polymeric carrier for protein delivery. , 2010, International journal of pharmaceutics.

[2]  Kwangmeyung Kim,et al.  Protease Imaging of Human Atheromata Captures Molecular Information of Atherosclerosis, Complementing Anatomic Imaging , 2010, Arteriosclerosis, thrombosis, and vascular biology.

[3]  Muri Han,et al.  Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[4]  Ick Chan Kwon,et al.  Activatable imaging probes with amplified fluorescent signals. , 2008, Chemical communications.

[5]  Igor L. Medintz,et al.  Quantum-dot/dopamine bioconjugates function as redox coupled assemblies for in vitro and intracellular pH sensing. , 2010, Nature materials.

[6]  G. Arteel,et al.  Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors. , 1999, Radiation research.

[7]  D. Vordermark,et al.  Green fluorescent protein is a suitable reporter of tumor hypoxia despite an oxygen requirement for chromophore formation. , 2001, Neoplasia.

[8]  Subinoy Rana,et al.  Nanoparticles for detection and diagnosis. , 2010, Advanced drug delivery reviews.

[9]  J. Reubi,et al.  Peptide-Based Probes for Cancer Imaging , 2008, Journal of Nuclear Medicine.

[10]  Sanjiv S Gambhir,et al.  Self-illuminating quantum dot conjugates for in vivo imaging , 2006, Nature Biotechnology.

[11]  U. Bunz α-Oligofurans: Molecules Without a Twist , 2010 .

[12]  U. Schubert,et al.  Poly(ethylene glycol) in drug delivery: pros and cons as well as potential alternatives. , 2010, Angewandte Chemie.

[13]  Jenn‐Shing Chen,et al.  Folic acid-Pluronic F127 magnetic nanoparticle clusters for combined targeting, diagnosis, and therapy applications. , 2009, Biomaterials.

[14]  P. Pelicci,et al.  Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? , 2007, Nature Reviews Molecular Cell Biology.

[15]  R. Simon,et al.  Acid-Sensing Ion Channels in Acidosis-Induced Injury of Human Brain Neurons , 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[16]  Ronghua Yang,et al.  Nucleic acid conjugated nanomaterials for enhanced molecular recognition. , 2009, ACS nano.

[17]  Yamuna Krishnan,et al.  A DNA nanomachine that maps spatial and temporal pH changes inside living cells. , 2009, Nature nanotechnology.

[18]  G Aicardi,et al.  Chemiluminescence imaging in bioanalysis. , 1998, Journal of pharmaceutical and biomedical analysis.

[19]  Tae Gwan Park,et al.  Fluorescent Gold Nanoprobe Sensitive to Intracellular Reactive Oxygen Species , 2009 .

[20]  Nicholas A Peppas,et al.  Targeted Nanodelivery of Drugs and Diagnostics. , 2010, Nano today.

[21]  R. Jain,et al.  Photodynamic therapy for cancer , 2003, Nature Reviews Cancer.

[22]  W. R. Taylor,et al.  In vivo imaging of hydrogen peroxide with chemiluminescent nanoparticles. , 2007, Nature materials.

[23]  J. Willmann,et al.  Molecular imaging in drug development , 2008, Nature Reviews Drug Discovery.

[24]  D. Huber,et al.  Synthesis, properties, and applications of iron nanoparticles. , 2005, Small.

[25]  Scott C. Brown,et al.  Nanoparticles for bioimaging. , 2006, Advances in colloid and interface science.

[26]  Ick Chan Kwon,et al.  Cell-permeable and biocompatible polymeric nanoparticles for apoptosis imaging. , 2006, Journal of the American Chemical Society.

[27]  A Paul Alivisatos,et al.  Continuous imaging of plasmon rulers in live cells reveals early-stage caspase-3 activation at the single-molecule level , 2009, Proceedings of the National Academy of Sciences.

[28]  Ajay Kumar Gupta,et al.  Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications. , 2007, Nanomedicine.

[29]  Valery A. Petrenko,et al.  Evolution of phage display: from bioactive peptides to bioselective nanomaterials , 2008 .

[30]  Hak Soo Choi,et al.  Design considerations for tumour-targeted nanoparticles. , 2010, Nature nanotechnology.

[31]  Xiaoyuan Chen,et al.  Applications for site-directed molecular imaging agents coupled with drug delivery potential , 2009, Expert opinion on drug delivery.

[32]  A. Mazar Urokinase Plasminogen Activator Receptor Choreographs Multiple Ligand Interactions: Implications for Tumor Progression and Therapy , 2008, Clinical Cancer Research.

[33]  Kornelia Polyak,et al.  Microenvironmental regulation of cancer development. , 2008, Current opinion in genetics & development.

[34]  D. Raghavan,et al.  Intra-tumoural extra-cellular pH: a useful parameter of response to chemotherapy in syngeneic tumour lines , 2009, British Journal of Cancer.

[35]  A. Horiguchi,et al.  Novel SN-38-incorporated polymeric micelle, NK012, strongly suppresses renal cancer progression. , 2008, Cancer research.

[36]  R. Weissleder,et al.  Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes. , 2002, Radiology.

[37]  Ralph Weissleder,et al.  Protease sensors for bioimaging , 2003, Analytical and bioanalytical chemistry.

[38]  Itamar Willner,et al.  Biomolecule-based nanomaterials and nanostructures. , 2010, Nano letters.

[39]  Ralph Weissleder,et al.  Near-infrared fluorescence: application to in vivo molecular imaging. , 2010, Current opinion in chemical biology.

[40]  A. Padhani,et al.  Science to practice: what does MR oxygenation imaging tell us about human breast cancer hypoxia? , 2010, Radiology.

[41]  Dai Fukumura,et al.  Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization. , 2007, Microvascular research.

[42]  J. McNamara,et al.  Ischemic Stroke “Acidotoxicity” Is a Perpetrator , 2004, Cell.

[43]  John V Frangioni,et al.  New technologies for human cancer imaging. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[44]  Xin Xu,et al.  NADPH oxidase contributes to coronary endothelial dysfunction in the failing heart. , 2009, American journal of physiology. Heart and circulatory physiology.

[45]  L. Kappelle,et al.  The value of near-infrared spectroscopy measured cerebral oximetry during carotid endarterectomy in perioperative stroke prevention. A review. , 2009, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[46]  J. Heinecke Oxidative stress: new approaches to diagnosis and prognosis in atherosclerosis. , 2003, The American journal of cardiology.

[47]  G. Semenza Targeting HIF-1 for cancer therapy , 2003, Nature Reviews Cancer.

[48]  J. Karp,et al.  Noninvasive imaging of tumor hypoxia in rats using the 2-nitroimidazole 18F-EF5 , 2003, European Journal of Nuclear Medicine and Molecular Imaging.

[49]  Ick Chan Kwon,et al.  Targeted delivery of low molecular drugs using chitosan and its derivatives. , 2010, Advanced drug delivery reviews.

[50]  Kwangmeyung Kim,et al.  Chemiluminescence‐Generating Nanoreactor Formulation for Near‐Infrared Imaging of Hydrogen Peroxide and Glucose Level in vivo , 2010 .

[51]  S. Kizaka-Kondoh,et al.  Significance of nitroimidazole compounds and hypoxia‐inducible factor‐1 for imaging tumor hypoxia , 2009, Cancer science.

[52]  Robert Langer,et al.  Nanotechnology in drug delivery and tissue engineering: from discovery to applications. , 2010, Nano letters.

[53]  Xiaohua Huang,et al.  Peptide-conjugated gold nanorods for nuclear targeting. , 2007, Bioconjugate chemistry.

[54]  Eva M. Sevick-Muraca,et al.  Dual-Labeled Trastuzumab-Based Imaging Agent for the Detection of Human Epidermal Growth Factor Receptor 2 Overexpression in Breast Cancer , 2007, Journal of Nuclear Medicine.

[55]  D. Boas,et al.  Dendritic phosphorescent probes for oxygen imaging in biological systems. , 2009, ACS Applied Materials and Interfaces.

[56]  David Piwnica-Worms,et al.  An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging. , 2009, Bioconjugate chemistry.

[57]  Kenneth A Krohn,et al.  Molecular Imaging of Hypoxia , 2008, Journal of Nuclear Medicine.

[58]  Jun Fang,et al.  Therapeutic strategies by modulating oxygen stress in cancer and inflammation. , 2009, Advanced drug delivery reviews.

[59]  Dai Fukumura,et al.  A nanoparticle size series for in vivo fluorescence imaging. , 2010, Angewandte Chemie.

[60]  Robert Langer,et al.  Self-assembled gold nanoparticle molecular probes for detecting proteolytic activity in vivo. , 2010, ACS nano.

[61]  M. Dewhirst,et al.  A dual-emissive-materials design concept enables tumour hypoxia imaging. , 2009, Nature materials.

[62]  G. Bartosz Use of spectroscopic probes for detection of reactive oxygen species. , 2006, Clinica chimica acta; international journal of clinical chemistry.

[63]  Sangjin Park,et al.  Thermally cross-linked superparamagnetic iron oxide nanoparticles: synthesis and application as a dual imaging probe for cancer in vivo. , 2007, Journal of the American Chemical Society.

[64]  Shaker A Mousa,et al.  Emerging nanomedicines for early cancer detection and improved treatment: current perspective and future promise. , 2010, Pharmacology & therapeutics.

[65]  L. H. Gray,et al.  The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. , 1953, The British journal of radiology.

[66]  R. Hill,et al.  Comparing techniques of measuring tumor hypoxia in different murine tumors: Eppendorf pO2 Histograph, [3H]misonidazole binding and paired survival assay. , 1996, Radiation research.

[67]  Babak Kateb,et al.  Infrared thermal imaging: A review of the literature and case report , 2009, NeuroImage.

[68]  Martin Moskovits,et al.  Aptamer-mediated surface-enhanced Raman spectroscopy intensity amplification. , 2010, Nano letters.

[69]  L. Matrisian,et al.  Matrix metalloproteinases: multifunctional contributors to tumor progression. , 2000, Molecular medicine today.

[70]  A. Dominiczak,et al.  Strategies to reduce oxidative stress in cardiovascular disease. , 2004, Clinical science.

[71]  Satish K. Nune,et al.  Nanoparticles for biomedical imaging , 2009, Expert opinion on drug delivery.

[72]  P. Jain,et al.  Au nanoparticles target cancer , 2007 .

[73]  Kwangmeyung Kim,et al.  Polymers for bioimaging , 2007 .

[74]  G. Lubec,et al.  Expression of proteasomal proteins in ten different tumor cell lines , 2004, Amino Acids.

[75]  Matthew Bogyo,et al.  Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes , 2009, Nature Medicine.

[76]  Ick Chan Kwon,et al.  Tumor-targeting peptide conjugated pH-responsive micelles as a potential drug carrier for cancer therapy. , 2010, Bioconjugate chemistry.

[77]  Dohyung Lim,et al.  Heparin-coated gold nanoparticles for liver-specific CT imaging. , 2009, Chemistry.

[78]  P. Choyke,et al.  New strategies for fluorescent probe design in medical diagnostic imaging. , 2010, Chemical reviews.

[79]  Zhen Cheng,et al.  Effects of nanoparticle size on cellular uptake and liver MRI with polyvinylpyrrolidone-coated iron oxide nanoparticles. , 2010, ACS nano.

[80]  Ick Chan Kwon,et al.  In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles. , 2010, Chemical communications.

[81]  Chad A Mirkin,et al.  Gold nanoparticles for biology and medicine. , 2010, Angewandte Chemie.

[82]  M. Hiraoka,et al.  Tumor hypoxia: A target for selective cancer therapy , 2003, Cancer science.

[83]  Geng Ku,et al.  Noninvasive imaging of hemoglobin concentration and oxygenation in the rat brain using high-resolution photoacoustic tomography. , 2006, Journal of biomedical optics.

[84]  Ralph Weissleder,et al.  Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes. , 2002, Bioconjugate chemistry.

[85]  K. Hong,et al.  Perfluorodecalin/[InGaP/ZnS quantum dots] nanoemulsions as 19F MR/optical imaging nanoprobes for the labeling of phagocytic and nonphagocytic immune cells. , 2010, Biomaterials.

[86]  G. Semenza,et al.  Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[87]  Ick Chan Kwon,et al.  Tumor-homing multifunctional nanoparticles for cancer theragnosis: Simultaneous diagnosis, drug delivery, and therapeutic monitoring. , 2010, Journal of Controlled Release.

[88]  C. Nathan,et al.  Production of large amounts of hydrogen peroxide by human tumor cells. , 1991, Cancer research.

[89]  H. Maeda,et al.  Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. , 2000, Journal of controlled release : official journal of the Controlled Release Society.

[90]  P Vaupel,et al.  Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements. , 1991, Cancer research.

[91]  U. Bunz Alpha-oligofurans: molecules without a twist. , 2010, Angewandte Chemie.

[92]  Ick Chan Kwon,et al.  New Generation of Multifunctional Nanoparticles for Cancer Imaging and Therapy , 2009 .

[93]  Zhen Cheng,et al.  Ultrasmall near-infrared non-cadmium quantum dots for in vivo tumor imaging. , 2010, Small.

[94]  B. Baxter,et al.  MMP Inhibition in Abdominal Aortic Aneurysms: Rationale for a Prospective Randomized Clinical Trial , 1999, Annals of the New York Academy of Sciences.

[95]  Gregory M Palmer,et al.  Stereocomplexed poly(lactic acid)-poly(ethylene glycol) nanoparticles with dual-emissive boron dyes for tumor accumulation. , 2010, ACS nano.

[96]  Christophe Van de Wiele,et al.  Molecular imaging of hypoxia with radiolabelled agents , 2009, European Journal of Nuclear Medicine and Molecular Imaging.

[97]  Vincent M Rotello,et al.  Gold nanoparticle-fluorophore complexes: sensitive and discerning "noses" for biosystems sensing. , 2010, Angewandte Chemie.

[98]  C. Ahn,et al.  Polymeric nanoparticle-based activatable near-infrared nanosensor for protease determination in vivo. , 2009, Nano letters.

[99]  Tristan Barrett,et al.  Selective molecular imaging of viable cancer cells with pH-activatable fluorescence probes , 2009, Nature Medicine.

[100]  Y. Bae,et al.  Trafficking microenvironmental pHs of polycationic gene vectors in drug-sensitive and multidrug-resistant MCF7 breast cancer cells. , 2010, Biomaterials.

[101]  Michael R Hamblin,et al.  Photodynamic therapy and anti-tumour immunity , 2006, Nature Reviews Cancer.

[102]  S. Lukyanov,et al.  Genetically encoded fluorescent indicator for intracellular hydrogen peroxide , 2006, Nature Methods.

[103]  Z. Fayad,et al.  Fractionated feridex and positive contrast: In vivo MR imaging of atherosclerosis , 2008, Magnetic resonance in medicine.

[104]  Masahiro Hiraoka,et al.  Optical Imaging of Tumor Hypoxia and Evaluation of Efficacy of a Hypoxia-Targeting Drug in Living Animals , 2005, Molecular imaging.

[105]  P. Schumacker,et al.  Reactive oxygen species in cancer cells: live by the sword, die by the sword. , 2006, Cancer cell.

[106]  Benjamin W. Dugan,et al.  Oxygen distributions in tissue measured by phosphorescence quenching. , 2003, Advances in experimental medicine and biology.

[107]  N. Soh Recent advances in fluorescent probes for the detection of reactive oxygen species , 2006, Analytical and bioanalytical chemistry.

[108]  S. Rhee,et al.  H2O2, a Necessary Evil for Cell Signaling , 2006, Science.

[109]  Kit S Lam,et al.  From combinatorial chemistry to cancer-targeting peptides. , 2007, Molecular pharmaceutics.

[110]  Y. Rustum,et al.  Lack of Microvessels in Well-Differentiated Regions of Human Head and Neck Squamous Cell Carcinoma A253 Associated with Functional Magnetic Resonance Imaging Detectable Hypoxia, Limited Drug Delivery, and Resistance to Irinotecan Therapy , 2004, Clinical Cancer Research.

[111]  M. Bawendi,et al.  Renal clearance of quantum dots , 2007, Nature Biotechnology.

[112]  Hyesung Jeon,et al.  Magnetite-nanoparticle-encapsulated pH-responsive polymeric micelle as an MRI probe for detecting acidic pathologic areas. , 2010, Small.

[113]  Seulki Lee,et al.  Peptides and peptide hormones for molecular imaging and disease diagnosis. , 2010, Chemical reviews.

[114]  Tae Gwan Park,et al.  Synthesis, characterization, and in vivo diagnostic applications of hyaluronic acid immobilized gold nanoprobes. , 2008, Biomaterials.

[115]  Chi V Dang,et al.  Cancer's molecular sweet tooth and the Warburg effect. , 2006, Cancer research.

[116]  Jin-Zhi Du,et al.  A tumor-acidity-activated charge-conversional nanogel as an intelligent vehicle for promoted tumoral-cell uptake and drug delivery. , 2010, Angewandte Chemie.

[117]  Seulki Lee,et al.  Peptide-based probes for targeted molecular imaging. , 2010, Biochemistry.

[118]  P. Vaupel,et al.  Hypoxia in cancer: significance and impact on clinical outcome , 2007, Cancer and Metastasis Reviews.

[119]  Joachim Wegener,et al.  A nanogel for ratiometric fluorescent sensing of intracellular pH values. , 2010, Angewandte Chemie.