Association of the CAV1‐CAV2 locus with normal‐tension glaucoma in Chinese and Japanese

The CAV1‐CAV2 locus has been associated with primary open‐angle glaucoma (POAG) and intraocular pressure. However, its association with normal‐tension glaucoma (NTG) was inconclusive. Therefore, we evaluated this association in Chinese and Japanese.

[1]  Wei Chen,et al.  Reduced Annexin A1 Secretion by ABCA1 Causes Retinal Inflammation and Ganglion Cell Apoptosis in a Murine Glaucoma Model , 2018, Front. Cell. Neurosci..

[2]  J. Haines,et al.  Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma , 2018, Human molecular genetics.

[3]  V. P. Costa,et al.  Investigation of CAV1/CAV2 rs4236601 and CDKN2B-AS1 rs2157719 in primary open-angle glaucoma patients from Brazil , 2018, Ophthalmic genetics.

[4]  N. Risch,et al.  A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure , 2017, Nature Communications.

[5]  Xinghuai Sun,et al.  Genetic Deletion of the NOS3 Gene in CAV1-/- Mice Restores Aqueous Humor Outflow Function. , 2017, Investigative ophthalmology & visual science.

[6]  L. Pasquale,et al.  Genetics of glaucoma , 2017, Human molecular genetics.

[7]  H. Yamada,et al.  Association of Glaucoma-Susceptible Genes to Regional Circumpapillary Retinal Nerve Fiber Layer Thickness and Visual Field Defects. , 2017, Investigative ophthalmology & visual science.

[8]  M. Elliott,et al.  Caveolins and caveolae in ocular physiology and pathophysiology , 2017, Progress in Retinal and Eye Research.

[9]  Adriana I. Iglesias,et al.  New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics , 2017, Human molecular genetics.

[10]  M. Tanito,et al.  Caveolin-1 modulates intraocular pressure: implications for caveolae mechanoprotection in glaucoma , 2016, Scientific Reports.

[11]  K. Nishida,et al.  Ethnic specific association of the CAV1/CAV2 locus with primary open-angle glaucoma , 2016, Scientific Reports.

[12]  Xinghuai Sun,et al.  eNOS Activity in CAV1 Knockout Mouse Eyes. , 2016, Investigative ophthalmology & visual science.

[13]  K. Park,et al.  Prevalence, Awareness, and Risk Factors of Primary Open-Angle Glaucoma: Korea National Health and Nutrition Examination Survey 2008-2011. , 2016, Ophthalmology.

[14]  Gabor T. Marth,et al.  A global reference for human genetic variation , 2015, Nature.

[15]  C. R. Ethier,et al.  Role of nitric oxide in murine conventional outflow physiology. , 2015, American journal of physiology. Cell physiology.

[16]  C. Kang,et al.  Expression-associated polymorphisms of CAV1-CAV2 affect intraocular pressure and high-tension glaucoma risk , 2015, Molecular vision.

[17]  Z. Yamagata,et al.  Involvement of genetic variants associated with primary open-angle glaucoma in pathogenic mechanisms and family history of glaucoma. , 2015, American journal of ophthalmology.

[18]  A. D. den Hollander,et al.  Association of known common genetic variants with primary open angle, primary angle closure, and pseudoexfoliation glaucoma in Pakistani cohorts , 2014, Molecular vision.

[19]  T. Wong,et al.  Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. , 2014, Ophthalmology.

[20]  T. Wong,et al.  Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma , 2014, Nature Genetics.

[21]  E. Ling,et al.  NF-κB-mediated nitric oxide production and activation of caspase-3 cause retinal ganglion cell death in the hypoxic neonatal retina. , 2014, Investigative ophthalmology & visual science.

[22]  F. Medeiros,et al.  The pathophysiology and treatment of glaucoma: a review. , 2014, JAMA.

[23]  Robert N Weinreb,et al.  Association of CAV1/CAV2 genomic variants with primary open-angle glaucoma overall and by gender and pattern of visual field loss. , 2014, Ophthalmology.

[24]  L. Pasquale,et al.  Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry. , 2013, Investigative ophthalmology & visual science.

[25]  H. Inoko,et al.  Association study of genetic variants on chromosome 7q31 with susceptibility to normal tension glaucoma in a Japanese population , 2013, Eye.

[26]  E. Tamm,et al.  The role of plasmalemma vesicle-associated protein (PLVAP) in endothelial cells of Schlemm's canal and ocular capillaries. , 2012, Experimental eye research.

[27]  K. Abu-Amero,et al.  Lack of association of SNP rs4236601 near CAV1 and CAV2 with POAG in a Saudi cohort , 2012, Molecular vision.

[28]  C. Lamaze,et al.  Stressing caveolae new role in cell mechanics. , 2012, Trends in cell biology.

[29]  M. C. Leske,et al.  CDKN2B Polymorphism Is Associated with Primary Open-Angle Glaucoma (POAG) in the Afro-Caribbean Population of Barbados, West Indies , 2012, PloS one.

[30]  A. Hofman,et al.  Common Genetic Determinants of Intraocular Pressure and Primary Open-Angle Glaucoma , 2012, PLoS genetics.

[31]  Stephanie Gogarten,et al.  Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA. , 2011, Human molecular genetics.

[32]  A. Surguchov,et al.  Expression of caveolin in trabecular meshwork cells and its possible implication in pathogenesis of primary open angle glaucoma , 2011, Molecular vision.

[33]  M. Brown,et al.  Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1 , 2011, Nature Genetics.

[34]  Young H. Kwon,et al.  Chromosome 7q31 POAG locus: ocular expression of caveolins and lack of association with POAG in a US cohort , 2011, Molecular vision.

[35]  A. Miyanohara,et al.  Loss of Caveolin-1 Accelerates Neurodegeneration and Aging , 2010, PloS one.

[36]  H. Stefánsson,et al.  Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma , 2010, Nature Genetics.

[37]  S. Park,et al.  Caveolin-1 as a Novel Indicator of Wound-Healing Capacity in Aged Human Corneal Epithelium , 2010, Molecular medicine.

[38]  C. Tham,et al.  Simvastatin and disease stabilization in normal tension glaucoma: a cohort study. , 2010, Ophthalmology.

[39]  S. Miglior,et al.  Risk factors for glaucoma onset and progression. , 2008, Survey of ophthalmology.

[40]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[41]  Yu-Chun Lin,et al.  Molecular interaction between caveolin-1 and ABCA1 on high-density lipoprotein-mediated cholesterol efflux in aortic endothelial cells. , 2007, Cardiovascular research.

[42]  J. Kane,et al.  High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture , 2006, British Journal of Ophthalmology.

[43]  W. Lo,et al.  Identification of caveolae and their signature proteins caveolin 1 and 2 in the lens. , 2004, Experimental eye research.

[44]  S. Thompson,et al.  Quantifying heterogeneity in a meta‐analysis , 2002, Statistics in medicine.

[45]  S. Gabriel,et al.  The Structure of Haplotype Blocks in the Human Genome , 2002, Science.

[46]  V. Ganapathy,et al.  A Comparison of Caveolae and Caveolin-1 to Folate Receptor α in Retina and Retinal Pigment Epithelium , 2001, The Histochemical Journal.

[47]  Y. Courtois,et al.  Requirement for Nitric Oxide in Retinal Neuronal Cell Death Induced by Activated Müller Glial Cells , 1999, Journal of neurochemistry.

[48]  D. Buerk,et al.  Nitric oxide has a vasodilatory role in cat optic nerve head during flicker stimuli. , 1996, Microvascular research.

[49]  R. Klein,et al.  Exome array analysis identifies CAV1/CAV2 as a susceptibility locus for intraocular pressure. , 2014, Investigative ophthalmology & visual science.

[50]  N. Breslow,et al.  Statistical methods in cancer research: volume 1- The analysis of case-control studies , 1980 .