Combination of active targeting, enzyme-triggered release and fluorescent dye into gold nanoclusters for endomicroscopy-guided photothermal/photodynamic therapy to pancreatic ductal adenocarcinoma.

[1]  Juyoung Yoon,et al.  Cancer‐Associated, Stimuli‐Driven, Turn on Theranostics for Multimodality Imaging and Therapy , 2017, Advanced materials.

[2]  Zhuang Liu,et al.  Near-Infrared-Triggered Photodynamic Therapy with Multitasking Upconversion Nanoparticles in Combination with Checkpoint Blockade for Immunotherapy of Colorectal Cancer. , 2017, ACS nano.

[3]  C. McCoy,et al.  Luminescent Lanthanide Cyclen-Based Enzymatic Assay Capable of Diagnosing the Onset of Catheter-Associated Urinary Tract Infections Both in Solution and within Polymeric Hydrogels. , 2017, Journal of the American Chemical Society.

[4]  Hui Wu,et al.  Photothermal therapy by using titanium oxide nanoparticles , 2016, Nano Research.

[5]  Jianjun Du,et al.  Fluorescent Probes for Sensing and Imaging within Specific Cellular Organelles. , 2016, Accounts of chemical research.

[6]  Min Qian,et al.  Photothermal combined gene therapy achieved by polyethyleneimine-grafted oxidized mesoporous carbon nanospheres. , 2016, Biomaterials.

[7]  K. Y. Zhang,et al.  A Mitochondria-Targeted Photosensitizer Showing Improved Photodynamic Therapy Effects Under Hypoxia. , 2016, Angewandte Chemie.

[8]  Min Qian,et al.  Facile growth of well-dispersed and ultra-small MoS2 nanodots in ordered mesoporous silica nanoparticles. , 2016, Chemical communications.

[9]  H. Tian,et al.  Real-Time Tracking and In Vivo Visualization of β-Galactosidase Activity in Colorectal Tumor with a Ratiometric Near-Infrared Fluorescent Probe. , 2016, Journal of the American Chemical Society.

[10]  Kai-Wen Huang,et al.  Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth In Vivo , 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

[11]  E. Akkaya,et al.  Remote-Controlled Release of Singlet Oxygen by the Plasmonic Heating of Endoperoxide-Modified Gold Nanorods: Towards a Paradigm Change in Photodynamic Therapy. , 2016, Angewandte Chemie.

[12]  Fang Zeng,et al.  A two-photon fluorescent sensor revealing drug-induced liver injury via tracking γ-glutamyltranspeptidase (GGT) level in vivo. , 2016, Biomaterials.

[13]  Shuo Diao,et al.  A small-molecule dye for NIR-II imaging. , 2016, Nature materials.

[14]  Brad A. Kairdolf,et al.  Intraoperative Spectroscopy with Ultrahigh Sensitivity for Image-Guided Surgery of Malignant Brain Tumors. , 2016, Analytical chemistry.

[15]  Zhuang Liu,et al.  Photosensitizer-Conjugated Albumin-Polypyrrole Nanoparticles for Imaging-Guided In Vivo Photodynamic/Photothermal Therapy. , 2015, Small.

[16]  Zhaochao Xu,et al.  Fluorescence imaging of metal ions implicated in diseases. , 2015, Chemical Society reviews.

[17]  Jiahong Zhou,et al.  Photo-triggered fluorescent theranostic prodrugs as DNA alkylating agents for mechlorethamine release and spatiotemporal monitoring. , 2015, Organic & biomolecular chemistry.

[18]  Peng Huang,et al.  Optical and photoacoustic dual-modality imaging guided synergistic photodynamic/photothermal therapies. , 2015, Nanoscale.

[19]  Zhuang Liu,et al.  Combined photothermal and photodynamic therapy delivered by PEGylated MoS2 nanosheets. , 2014, Nanoscale.

[20]  Yingsheng Cheng,et al.  Monitoring Pancreatic Carcinogenesis by the Molecular Imaging of Cathepsin E In Vivo Using Confocal Laser Endomicroscopy , 2014, PloS one.

[21]  S. Gill,et al.  Chemotherapy regimens for advanced pancreatic cancer: a systematic review and network meta-analysis , 2014, BMC Cancer.

[22]  Zhuang Liu,et al.  Protein modified upconversion nanoparticles for imaging-guided combined photothermal and photodynamic therapy. , 2014, Biomaterials.

[23]  Wei Feng,et al.  Hollow silica nanoparticles loaded with hydrophobic phthalocyanine for near-infrared photodynamic and photothermal combination therapy. , 2013, Biomaterials.

[24]  Cesar M. Castro,et al.  Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection. , 2013, Neoplasia.

[25]  C. Tung,et al.  Pancreatic cancer-associated Cathepsin E as a drug activator. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[26]  Guangxia Shen,et al.  Light‐Triggered Theranostics Based on Photosensitizer‐Conjugated Carbon Dots for Simultaneous Enhanced‐Fluorescence Imaging and Photodynamic Therapy , 2012, Advanced materials.

[27]  C. Tung,et al.  Selective detection of Cathepsin E proteolytic activity. , 2010, Biochimica et biophysica acta.

[28]  M. Moore,et al.  Advanced pancreatic carcinoma: current treatment and future challenges , 2010, Nature Reviews Clinical Oncology.

[29]  S. Nie,et al.  Molecular imaging of pancreatic cancer in an animal model using targeted multifunctional nanoparticles. , 2009, Gastroenterology.

[30]  Yong Zhang,et al.  Nanoparticles in photodynamic therapy: an emerging paradigm. , 2008, Advanced drug delivery reviews.

[31]  S. Elmore Apoptosis: A Review of Programmed Cell Death , 2007, Toxicologic pathology.

[32]  P. Bjerring,et al.  5‐ALA for photodynamic photorejuvenation—optimization of treatment regime based on normal‐skin fluorescence measurements , 2007, Lasers in surgery and medicine.

[33]  A. Cooper,et al.  Formation of spherical nanostructures by the controlled aggregation of gold colloids. , 2006, Langmuir : the ACS journal of surfaces and colloids.

[34]  D. V. Von Hoff,et al.  Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[35]  M. Brust,et al.  Novel gold‐dithiol nano‐networks with non‐metallic electronic properties , 1995 .

[36]  A. Wyllie,et al.  Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics , 1972, British Journal of Cancer.

[37]  X. Qu,et al.  A Multi‐synergistic Platform for Sequential Irradiation‐Activated High‐Performance Apoptotic Cancer Therapy , 2014 .

[38]  Andrew D. Miller,et al.  Targeting the urokinase plasminogen activator receptor with synthetic self-assembly nanoparticles. , 2009, Bioconjugate chemistry.

[39]  H. Friess,et al.  Enhanced expression of urokinase plasminogen activator and its receptor in pancreatic carcinoma. , 1997, British Journal of Cancer.