Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease

[1]  M. Chakravarty,et al.  Genome‐wide variant by serum urate interaction in Parkinson's disease , 2015, Annals of neurology.

[2]  Timothy J. Hohman,et al.  GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension , 2015, Neurotoxicity Research.

[3]  S. Leurgans,et al.  Effect of common neuropathologies on progression of late life cognitive impairment , 2015, Neurobiology of Aging.

[4]  W. M. van der Flier,et al.  Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage. , 2015, Brain : a journal of neurology.

[5]  C. Jack,et al.  Nonlinear Association Between Cerebrospinal Fluid and Florbetapir F-18 β-Amyloid Measures Across the Spectrum of Alzheimer Disease. , 2015, JAMA neurology.

[6]  D. Holtzman,et al.  Three dimensions of the amyloid hypothesis: time, space and 'wingmen' , 2015, Nature Neuroscience.

[7]  Charles C. White,et al.  A TREM1 variant alters the accumulation of Alzheimer‐related amyloid pathology , 2015, Annals of neurology.

[8]  Miguel Ángel Martínez,et al.  Genetic overlap between Alzheimer’s disease and Parkinson’s disease at the MAPT locus , 2015, Molecular Psychiatry.

[9]  Shuo Zhang,et al.  Predictive Accuracy of Amyloid Imaging for Progression From Mild Cognitive Impairment to Alzheimer Disease With Different Lengths of Follow-up , 2014, Medicine.

[10]  Arno Klein,et al.  Large-scale evaluation of ANTs and FreeSurfer cortical thickness measurements , 2014, NeuroImage.

[11]  A. Singleton,et al.  Genetic variability in the regulation of gene expression in ten regions of the human brain , 2014, Nature Neuroscience.

[12]  L. V. Van Eldik,et al.  Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin , 2014, Molecular Neurodegeneration.

[13]  H. Saji,et al.  Feasibility of Amylin Imaging in Pancreatic Islets with β-Amyloid Imaging Probes , 2014, Scientific Reports.

[14]  W. Qiu,et al.  Amylin and its analogs: a friend or foe for the treatment of Alzheimer's disease? , 2014, Front. Aging Neurosci..

[15]  D. Bates,et al.  Fitting Linear Mixed-Effects Models Using lme4 , 2014, 1406.5823.

[16]  Stephen M. Smith,et al.  Permutation inference for the general linear model , 2014, NeuroImage.

[17]  Hyoung-Gon Lee,et al.  Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition , 2014, Neurobiology of Aging.

[18]  A. Dedeoglu,et al.  Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer's disease , 2014, Molecular Psychiatry.

[19]  Annette Lee,et al.  Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder , 2013, Nature Communications.

[20]  C. DeCarli,et al.  Amylin deposition in the brain: A second amyloid in Alzheimer disease? , 2013, Annals of Neurology.

[21]  J. Jhamandas,et al.  Amylin Receptor: A Common Pathophysiological Target in Alzheimer’s Disease and Diabetes Mellitus , 2013, Front. Aging Neurosci..

[22]  Jonathan P. Beauchamp,et al.  GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment , 2013, Science.

[23]  J. Morris,et al.  Comparison of symptomatic and asymptomatic persons with Alzheimer disease neuropathology , 2013, Neurology.

[24]  S Purcell,et al.  Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC , 2013, Molecular Psychiatry.

[25]  Ellen T. Gelfand,et al.  The Genotype-Tissue Expression (GTEx) project , 2013, Nature Genetics.

[26]  C. Jack,et al.  Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers , 2013, The Lancet Neurology.

[27]  M. Mintun,et al.  Amyloid-β Imaging with Pittsburgh Compound B and Florbetapir: Comparing Radiotracers and Quantification Methods , 2013, The Journal of Nuclear Medicine.

[28]  O. Delaneau,et al.  Supplementary Information for ‘ Improved whole chromosome phasing for disease and population genetic studies ’ , 2012 .

[29]  David Levine,et al.  GWASTools: an R/Bioconductor package for quality control and analysis of genome-wide association studies , 2012, Bioinform..

[30]  A. Morris,et al.  Genome-wide association meta-analysis identifies new endometriosis risk loci , 2012, Nature Genetics.

[31]  R. Wilson,et al.  Relation of neuropathology to cognition in persons without cognitive impairment , 2012, Annals of neurology.

[32]  Bronwen L. Aken,et al.  GENCODE: The reference human genome annotation for The ENCODE Project , 2012, Genome research.

[33]  David Haussler,et al.  The UCSC genome browser and associated tools , 2012, Briefings Bioinform..

[34]  Bruce Fischl,et al.  Within-subject template estimation for unbiased longitudinal image analysis , 2012, NeuroImage.

[35]  J. Schneider,et al.  Overview and findings from the religious orders study. , 2012, Current Alzheimer research.

[36]  J. Schneider,et al.  Overview and findings from the rush Memory and Aging Project. , 2012, Current Alzheimer research.

[37]  D. Bennett,et al.  Dementia from Alzheimer disease and mixed pathologies in the oldest old. , 2012, JAMA.

[38]  Jason J. Corneveaux,et al.  A genome-wide scan for common variants affecting the rate of age-related cognitive decline , 2012, Neurobiology of Aging.

[39]  J. Schneider,et al.  National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease , 2012, Alzheimer's & Dementia.

[40]  Thomas Lumley,et al.  Behavior of QQ-Plots and Genomic Control in Studies of Gene-Environment Interaction , 2011, PloS one.

[41]  Arno Klein,et al.  A reproducible evaluation of ANTs similarity metric performance in brain image registration , 2011, NeuroImage.

[42]  R. Coleman,et al.  Use of florbetapir-PET for imaging beta-amyloid pathology. , 2011, JAMA.

[43]  J. Morris,et al.  Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease , 2010, Science.

[44]  A. Morris,et al.  Data quality control in genetic case-control association studies , 2010, Nature Protocols.

[45]  Mark E. Schmidt,et al.  The Alzheimer's Disease Neuroimaging Initiative: Progress report and future plans , 2010, Alzheimer's & Dementia.

[46]  Owen Carmichael,et al.  Update on the Magnetic Resonance Imaging core of the Alzheimer's Disease Neuroimaging Initiative , 2010, Alzheimer's & Dementia.

[47]  Lisa Geraci,et al.  How Well Do the ADAS-cog and its Subscales Measure Cognitive Dysfunction in Alzheimer’s Disease? , 2009, Dementia and Geriatric Cognitive Disorders.

[48]  P. Donnelly,et al.  A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies , 2009, PLoS genetics.

[49]  Brian B. Avants,et al.  Registration based cortical thickness measurement , 2009, NeuroImage.

[50]  R. Petersen,et al.  Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects , 2009, Annals of neurology.

[51]  Moo K. Chung,et al.  A study of diffusion tensor imaging by tissue-specific, smoothing-compensated voxel-based analysis , 2009, NeuroImage.

[52]  H. Braak,et al.  Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship , 2009, Journal of neuropathology and experimental neurology.

[53]  D. Perl,et al.  Role of the neuropathology of Alzheimer disease in dementia in the oldest-old. , 2008, Archives of neurology.

[54]  H. Braak,et al.  Parenchymal and vascular Aβ-deposition and its effects on the degeneration of neurons and cognition in Alzheimer's disease , 2008, Journal of cellular and molecular medicine.

[55]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[56]  A. Joachimiak,et al.  Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism , 2006, Nature.

[57]  J. Jhamandas,et al.  Galanin attenuates β-amyloid (Aβ) toxicity in rat cholinergic basal forebrain neurons , 2006, Neurobiology of Disease.

[58]  J. Jhamandas,et al.  Antagonist of the Amylin Receptor Blocks β-Amyloid Toxicity in Rat Cholinergic Basal Forebrain Neurons , 2004, The Journal of Neuroscience.

[59]  J. Schneider,et al.  Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function. , 2004, Archives of neurology.

[60]  J. Kulisevsky,et al.  Rey verbal learning test is a useful tool for differential diagnosis in the preclinical phase of Alzheimer's disease: comparison with mild cognitive impairment and normal aging , 2003, International journal of geriatric psychiatry.

[61]  J. Schneider,et al.  Education modifies the relation of AD pathology to level of cognitive function in older persons , 2003, Neurology.

[62]  J. Morrison,et al.  Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease , 2003, Neurology.

[63]  M. Mesulam,et al.  Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment. , 2003, Archives of neurology.

[64]  P. Cleary,et al.  Racial disparities in access to renal transplantation--clinically appropriate or due to underuse or overuse? , 2000, The New England journal of medicine.

[65]  B. Ahrén,et al.  Islet amyloid and type 2 diabetes mellitus. , 2000, The New England journal of medicine.

[66]  P. May,et al.  Neurotoxicity of Human Amylin in Rat Primary Hippocampal Cultures: Similarity to Alzheimer's Disease Amyloid‐β Neurotoxicity , 1993, Journal of neurochemistry.

[67]  E. Masliah,et al.  Diffuse plaques do not accentuate synapse loss in Alzheimer's disease. , 1990, The American journal of pathology.

[68]  R. Au,et al.  Positive association between plasma amylin and cognition in a homebound elderly population. , 2014, Journal of Alzheimer's disease : JAD.

[69]  P. Brockhoff,et al.  lmerTest: Tests for random and fixed effects for linear mixed effect models (lmer objects of lme4 package) , 2014 .

[70]  D. Selkoe Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.

[71]  Tanya M. Teslovich,et al.  LocusZoom: regional visualization of genome-wide association scan results , 2010, Bioinform..

[72]  J. Hardy,et al.  The Amyloid Hypothesis of Alzheimer ’ s Disease : Progress and Problems on the Road to Therapeutics , 2009 .

[73]  W. Wien,et al.  Econometric Computing with HC and HAC Covariance Matrix Estimators , 2004 .