New insights into the mode of action of the actin ADP-ribosylating virulence factors Salmonella enterica SpvB and Clostridium botulinum C2 toxin.
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[1] H. Barth,et al. Clostridium botulinum C2 toxin is internalized by clathrin‐ and Rho‐dependent mechanisms , 2010, Cellular microbiology.
[2] R. Fieldhouse,et al. Photox, a Novel Actin-targeting Mono-ADP-ribosyltransferase from Photorhabdus luminescens , 2010, The Journal of Biological Chemistry.
[3] A. Tauch,et al. Functional Characterization of an Extended Binding Component of the Actin-ADP-Ribosylating C2 Toxin Detected in Clostridium botulinum Strain (C) 2300 , 2010, Infection and Immunity.
[4] H. Barth,et al. The Long-Lived Nature of Clostridium perfringens Iota Toxin in Mammalian Cells Induces Delayed Apoptosis , 2009, Infection and Immunity.
[5] J. Wehland,et al. Clostridium difficile Toxin CDT Induces Formation of Microtubule-Based Protrusions and Increases Adherence of Bacteria , 2009, PLoS pathogens.
[6] H. Barth,et al. Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells , 2009, Cellular microbiology.
[7] H. Barth,et al. ADP-Ribosylation of Actin by the Clostridium botulinum C2 Toxin in Mammalian Cells Results in Delayed Caspase-Dependent Apoptotic Cell Death , 2008, Infection and Immunity.
[8] H. Barth,et al. Binary actin-ADP-ribosylating toxins and their use as molecular Trojan horses for drug delivery into eukaryotic cells. , 2008, Current medicinal chemistry.
[9] K. Aktories,et al. A Cell-permeable Fusion Toxin as a Tool to Study the Consequences of Actin-ADP-ribosylation Caused by the Salmonella enterica Virulence Factor SpvB in Intact Cells* , 2007, Journal of Biological Chemistry.
[10] G. Schulz,et al. Structure and action of the binary C2 toxin from Clostridium botulinum. , 2006, Journal of molecular biology.
[11] K. Aktories,et al. Formation of a biologically active toxin complex of the binary Clostridium botulinum C2 toxin without cell membrane interaction. , 2006, Biochemistry.
[12] C. E. Stebbins,et al. A steric antagonism of actin polymerization by a salmonella virulence protein. , 2006, Structure.
[13] K. Aktories,et al. Salmonella enterica SpvB ADP-ribosylates actin at position arginine-177-characterization of the catalytic domain within the SpvB protein and a comparison to binary clostridial actin-ADP-ribosylating toxins. , 2006, Biochemistry.
[14] L. Engstrand,et al. Salmonella enterica SpvB-mediated ADP-ribosylation as an activator for host cell actin degradation. , 2005, International journal of medical microbiology : IJMM.
[15] D. Guiney,et al. Targeting of the actin cytoskeleton during infection by Salmonella strains. , 2005, Clinical immunology.
[16] K. Aktories,et al. Binary Bacterial Toxins: Biochemistry, Biology, and Applications of Common Clostridium and Bacillus Proteins , 2004, Microbiology and Molecular Biology Reviews.
[17] Klaus Aktories,et al. The Host Cell Chaperone Hsp90 Is Necessary for Cytotoxic Action of the Binary Iota-Like Toxins , 2004, Infection and Immunity.
[18] K. Aktories,et al. Cellular uptake of Clostridium botulinum C2 toxin: membrane translocation of a fusion toxin requires unfolding of its dihydrofolate reductase domain. , 2003, Biochemistry.
[19] Dirk Tiemann,et al. The Host Cell Chaperone Hsp90 Is Essential for Translocation of the Binary Clostridium botulinum C2 Toxin into the Cytosol* , 2003, Journal of Biological Chemistry.
[20] Y. Kikuchi,et al. Intracellular expression of the Salmonella plasmid virulence protein, SpvB, causes apoptotic cell death in eukaryotic cells. , 2003, Microbial pathogenesis.
[21] R. Benz,et al. Channel formation by the binding component of Clostridium botulinum C2 toxin: glutamate 307 of C2II affects channel properties in vitro and pH-dependent C2I translocation in vivo. , 2003, Biochemistry.
[22] R. Benz,et al. Clostridium botulinum C2 toxin: Low pH-induced pore formation is required for translocation of the enzyme component C2I into the cytosol of host cells , 2003 .
[23] K. Aktories,et al. The Binary Clostridium botulinum C2 Toxin as a Protein Delivery System , 2002, The Journal of Biological Chemistry.
[24] K. Aktories,et al. Characterization of the Enzymatic Component of the ADP-Ribosyltransferase Toxin CDTa from Clostridium difficile , 2001, Infection and Immunity.
[25] R. Benz,et al. Interaction of Clostridium botulinum C2‐toxin with lipid bilayer membranes and vero cells: inhibition of channel function by chloroquine and related compounds in vitro and intoxification in vivo , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[26] N. Reiner,et al. The Salmonella spvB virulence gene encodes an enzyme that ADP‐ribosylates actin and destabilizes the cytoskeleton of eukaryotic cells , 2001, Molecular microbiology.
[27] F. Koch-Nolte,et al. Actin is ADP‐ribosylated by the Salmonella enterica virulence‐associated protein SpvB , 2001, Molecular microbiology.
[28] J. Vandekerckhove,et al. Botulinum C 2 Toxin ADP-ribosylates Cytoplasmic @ / ?-Actin in Arginine 177 * , 2001 .
[29] F. Koch-Nolte,et al. The spvB gene‐product of the Salmonella enterica virulence plasmid is a mono(ADP‐ribosyl)transferase , 2000, Molecular microbiology.
[30] R. Benz,et al. Cellular Uptake of Clostridium botulinum C2 Toxin Requires Oligomerization and Acidification* , 2000, The Journal of Biological Chemistry.
[31] K. Aktories,et al. Binding of Clostridium botulinum C2 Toxin to Asparagine-linked Complex and Hybrid Carbohydrates* , 2000, The Journal of Biological Chemistry.
[32] I. Ohishi. Structure and Function of Actin-Adenosine-Diphosphate-Ribosylating Toxins , 2000 .
[33] M. Aepfelbacher,et al. Bacterial Protein Toxins , 2000, Handbook of Experimental Pharmacology.
[34] V. Kinzel,et al. Clostridium botulinum C2 Toxin Delays Entry into Mitosis and Activation of p34cdc2Kinase and cdc25-C Phosphatase in HeLa cells , 1999, Infection and Immunity.
[35] J. Tainer,et al. Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex , 1999, Nature Structural Biology.
[36] K. Aktories,et al. Characterization of the Catalytic Site of the ADP-Ribosyltransferase Clostridium botulinum C2 Toxin by Site-directed Mutagenesis* , 1998, The Journal of Biological Chemistry.
[37] K. Aktories,et al. The N-Terminal Part of the Enzyme Component (C2I) of the BinaryClostridium botulinum C2 Toxin Interacts with the Binding Component C2II and Functions as a Carrier System for a Rho ADP-Ribosylating C3-Like Fusion Toxin , 1998, Infection and Immunity.
[38] G. Corthier,et al. Production of a complete binary toxin (actin-specific ADP-ribosyltransferase) by Clostridium difficile CD196 , 1997, Infection and immunity.
[39] M. Mock,et al. Immunological and functional comparison between Clostridium perfringens iota toxin, C. spiroforme toxin, and anthrax toxins. , 1997, FEMS microbiology letters.
[40] P. Grob,et al. In vitro binding of the Salmonella dublin virulence plasmid regulatory protein SpvR to the promoter regions of spvA and spvR , 1996, Journal of bacteriology.
[41] F. Fang,et al. Growth-phase regulation of plasmid virulence genes in Salmonella. , 1995, Trends in microbiology.
[42] R. Benz,et al. Interaction of Clostridium botulinum C2 toxin with lipid bilayer membranes. Formation of cation-selective channels and inhibition of channel function by chloroquine. , 1994, The Journal of biological chemistry.
[43] K. Aktories,et al. Actin-gelsolin interaction. , 1994, Advances in experimental medicine and biology.
[44] K. Aktories,et al. Gelsolin-actin complex is target for ADP-ribosylation by Clostridium botulinum C2 toxin in intact human neutrophils. , 1993, European journal of pharmacology.
[45] K. Aktories,et al. ADP-ribosylation of gelsolin-actin complexes by clostridial toxins. , 1992, The Journal of biological chemistry.
[46] F. Fang,et al. Growth regulation of a Salmonella plasmid gene essential for virulence , 1991, Journal of bacteriology.
[47] P. Traub,et al. Alteration of the cytoskeleton of mammalian cells cultured in vitro by Clostridium botulinum C2 toxin and C3 ADP-ribosyltransferase. , 1991, European journal of cell biology.
[48] G. Gabbiani,et al. ADP-ribosylation of actin isoforms by Clostridium botulinum C2 toxin and Clostridium perfringens iota toxin. , 1990, European journal of biochemistry.
[49] W. Kabsch,et al. Atomic model of the actin filament , 1990, Nature.
[50] K. Aktories,et al. Inhibition of cytochalasin D-stimulated G-actin ATPase by ADP-ribosylation with Clostridium perfringens iota toxin. , 1990, The Biochemical journal.
[51] K. Aktories,et al. ADP-ribosylation of actin by clostridial toxins , 1989, The Journal of cell biology.
[52] K. Aktories,et al. Nonmuscle actin ADP‐ribosylated by botulinum C2 toxin caps actin filaments , 1989, FEBS letters.
[53] K. Aktories,et al. ADP-ribosylation of actin causes increase in the rate of ATP exchange and inhibition of ATP hydrolysis. , 1989, European journal of biochemistry.
[54] K. Aktories,et al. ADP-ribosylated actin caps the barbed ends of actin filaments. , 1988, The Journal of biological chemistry.
[55] E. Rubin,et al. Actin-specific ADP-ribosyltransferase produced by a Clostridium difficile strain , 1988, Infection and immunity.
[56] P. Boquet,et al. Clostridium spiroforme toxin is a binary toxin which ADP-ribosylates cellular actin. , 1988, Biochemical and biophysical research communications.
[57] J. Vandekerckhove,et al. Botulinum C2 toxin ADP-ribosylates cytoplasmic beta/gamma-actin in arginine 177. , 1988, The Journal of biological chemistry.
[58] K. Aktories,et al. ADP-ribosylation of skeletal muscle and non-muscle actin by Clostridium perfringens iota toxin. , 1988, European journal of biochemistry.
[59] J. Vandekerckhove,et al. Clostridium perfringens iota toxin ADP‐ribosylates skeletal muscle actin in Arg‐177 , 1987, FEBS letters.
[60] I. Ohishi,et al. Response of tissue-cultured cynomolgus monkey kidney cells to botulinum C2 toxin. , 1987, Microbial pathogenesis.
[61] I. Ohishi. Activation of botulinum C2 toxin by trypsin , 1987, Infection and immunity.
[62] Boschek Cb,et al. Botulinum C2 toxin ADP-ribosylates actin and disorganizes the microfilament network in intact cells. , 1987, European journal of cell biology.
[63] M. Popoff. Purification and characterization of Clostridium sordellii lethal toxin and cross-reactivity with Clostridium difficile cytotoxin , 1987, Infection and immunity.
[64] T. Wilkins,et al. Purification and characterization of Clostridium perfringens iota toxin: dependence on two nonlinked proteins for biological activity , 1986, Infection and immunity.
[65] K. Jakobs,et al. Botulinum C2 toxin ADP-ribosylates actin , 1986, Nature.
[66] H. Ogura,et al. Cytopathic effect of botulinum C2 toxin on tissue‐culture cells , 1984 .
[67] I. Ohishi,et al. Histopathological effect of botulinum C2 toxin on mouse intestines , 1984, Infection and immunity.
[68] I. Ohishi. Response of mouse intestinal loop to botulinum C2 toxin: enterotoxic activity induced by cooperation of nonlinked protein components , 1983, Infection and immunity.
[69] I. Ohishi. Lethal and vascular permeability activities of botulinum C2 toxin induced by separate injections of the two toxin components , 1983, Infection and immunity.
[70] L. Simpson. A comparison of the pharmacological properties of Clostridium botulinum type C1 and C2 toxins. , 1982, The Journal of pharmacology and experimental therapeutics.
[71] G. Sakaguchi,et al. Vascular permeability activity of botulinum C2 toxin elicited by cooperation of two dissimilar protein components , 1981, Infection and immunity.
[72] G. Sakaguchi,et al. Purification and characterization of two components of botulinum C2 toxin , 1980, Infection and immunity.