Differentiation-linked leukemogenesis in lymphocytes.

Most human lymphoid malignancies preserve a pattern of gene expression reflecting their proliferative activity and the development level of clonal expansion and maturation arrest. Characteristics of leukemia and other cancer cells frequently considered to reflect aberrant differentiation may more often reflect clonal selection of cell types that are normally infrequent and transitory. The differentiation status of progenitor or mature lymphoid cells influences which genetic elements are at risk of being exploited, via mutation, recombination, or deletion, for clonal advantage. These alterations may frequently arise spontaneously as a consequence of the unique developmental and functional programs of lymphoid cells and have as a major phenotypic consequence the stabilization of transitory cellular phenotypes.

[1]  M. Greaves,et al.  IS SPONTANEOUS MUTATION THE MAJOR ‘CAUSE’ OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKAEMIA? , 1986, British journal of haematology.

[2]  D. Gold,et al.  Developmentally regulated rearrangement and expression of genes encoding the T cell receptor-T3 complex , 1986, Cell.

[3]  F. Hecht,et al.  Cytogenetic and immunophenotypic analysis of cell lines established from patients with T cell leukemia/lymphoma. , 1986, Blood.

[4]  M. Greaves,et al.  Clonal rearrangement and expression of the T cell receptor beta gene and involvement of the breakpoint cluster region in blast crisis of CGL. , 1986, Blood.

[5]  L. Hood,et al.  Introduced T cell receptor variable region gene segments recombine in pre-B cells: Evidence that B and T cells use a common recombinase , 1986, Cell.

[6]  J. Scheres,et al.  Possible involvement of unstable sites on chromosomes 7 and 14 in human cancer. , 1986, Cancer genetics and cytogenetics.

[7]  I. Bernstein,et al.  Leukocyte Typing II , 1986, Springer New York.

[8]  M. Greaves,et al.  Lineage promiscuity in hemopoietic differentiation and leukemia. , 1986, Blood.

[9]  J. Habeshaw,et al.  Expression of burkitt lymphoma‐associated antigen (defined by the monoclonal antibody 38.13) on both normal and malignant germinal‐centre B cells , 1985, International journal of cancer.

[10]  V. Najfeld,et al.  Evidence for clonal development of childhood acute lymphoblastic leukemia. , 1985, Blood.

[11]  K. Lennert,et al.  The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells. , 1985, Blood.

[12]  C. Croce,et al.  The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. , 1985, Science.

[13]  H. Ochs,et al.  Echovirus encephalitis/myositis in X-linked agammaglobulinemia. , 1985, The New England journal of medicine.

[14]  J. Ritz,et al.  Orderly expression of B cell antigens during the in vitro differentiation of nonmalignant human pre-B cells. , 1985, Journal of immunology.

[15]  B. Haynes,et al.  Human T cell antigen expression during the early stages of fetal thymic maturation. , 1985, Journal of immunology.

[16]  E. Reinherz,et al.  Genes encoding the T-cell receptor alpha and beta subunits are transcribed in an ordered manner during intrathymic ontogeny. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[17]  J. Rowley,et al.  Lymphoblastic leukemia with lymphomatous features associated with abnormalities of the short arm of chromosome 9. , 1985, The New England journal of medicine.

[18]  T. Waldmann,et al.  Human γ-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7 , 1985, Nature.

[19]  N. Arnheim,et al.  Antibodies specific for amino acid 12 of the ras oncogene product inhibit GTP binding. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[20]  N. Copeland,et al.  Loss of heterozygosity in three embryonal tumours suggests a common pathogenetic mechanism , 1985, Nature.

[21]  H. Rubin.  Cancer as a dynamic developmental disorder. , 1985, Cancer research.

[22]  S. Tonegawa,et al.  Regulation of T-cell receptor gene expression in human T-cell development. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[23]  E. Canaani,et al.  Fused transcript of abl and bcr genes in chronic myelogenous leukaemia , 1985, Nature.

[24]  C. Spurr,et al.  Sequential high-dose ara-C and asparaginase in the therapy of previously treated and untreated patients with acute leukemia. , 1985, Seminars in oncology.

[25]  C. Marshall,et al.  Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia , 1985, Nature.

[26]  L. Arnold,et al.  Cross-reactive idiotypes and common antigen binding specificities expressed by a series of murine B-cell lymphomas: etiological implications. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[27]  P. Duesberg.  Activated proto-onc genes: sufficient or necessary for cancer? , 1985, Science.

[28]  U. Francke,et al.  Gene for human insulin receptor: localization to site on chromosome 19 involved in pre-B-cell leukemia. , 1985, Science.

[29]  J. Seidman,et al.  Genes for beta chain of human T-cell antigen receptor map to regions of chromosomal rearrangement in T cells. , 1985, Science.

[30]  P. Nowell,et al.  Location of gene for beta subunit of human T-cell receptor at band 7q35, a region prone to rearrangements in T cells. , 1985, Science.

[31]  J. P. Lewis,et al.  Cytogenetic evidence that the malignant event in multiple myeloma occurs in a precursor lymphocyte. , 1985, Cancer genetics and cytogenetics.

[32]  A. Knudson.  Hereditary cancer, oncogenes, and antioncogenes. , 1985, Cancer research.

[33]  T. Waldmann,et al.  NIH conference. Molecular genetic analysis of human lymphoid neoplasms. Immunoglobulin genes and the c-myc oncogene. , 1985, Annals of internal medicine.

[34]  T. Feizi.  Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens , 1985, Nature.

[35]  S. Pegram,et al.  CONTRIBUTION OF IMMUNOPHENOTYPE TO THE CLASSIFICATION AND DIFFERENTIAL DIAGNOSIS OF ACUTE LEUKAEMIA , 1985, The Lancet.

[36]  D. Campana,et al.  Human B cell development. I. Phenotypic differences of B lymphocytes in the bone marrow and peripheral lymphoid tissue. , 1985, Journal of immunology.

[37]  A. Palumbo,et al.  Gene for alpha-chain of human T-cell receptor: location on chromosome 14 region involved in T-cell neoplasms. , 1985, Science.

[38]  O. Witte,et al.  Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[39]  G. Miller,et al.  Epstein-Barr virus genomes are restricted to secondary neoplastic cells following bone marrow transplantation. , 1985, Blood.

[40]  S. Stass,et al.  Rearrangement of immunoglobulin heavy chain genes in T cell acute lymphoblastic leukemia. , 1985, Blood.

[41]  C. Pui,et al.  Clinical and biologic correlates of insulin binding by leukemia lymphoblasts. , 1985, Leukemia research.

[42]  R. Braziel,et al.  Induction of immunoglobulin secretion in follicular non-Hodgkin's lymphomas: role of immunoregulatory T cells. , 1985, Blood.

[43]  P. Nowell,et al.  Molecular basis of human B cell neoplasia. , 1985, Blood.

[44]  D. Fisher,et al.  Hairy cell leukemia: a tumor of pre-plasma cells. , 1985, Blood.

[45]  D. Delia,et al.  Phenotype of the terminal transferase-positive cells in human foetal liver and bone-marrow: analysis with monoclonal antibodies. , 2009, Scandinavian journal of haematology.

[46]  T. Mak,et al.  Sequence and expression of transcripts of the human T-cell receptor β- chain genes , 1984, Nature.

[47]  T. Graf,et al.  Autocrine growth induced by src-related oncogenes in transformed chicken myeloid cells , 1984, Cell.

[48]  M. Minden,et al.  Immunoglobulin gene rearrangement in acute myelogenous leukemia. , 1984, Cancer research.

[49]  David Baltimore,et al.  Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells , 1984, Nature.

[50]  E. Farber.  The multistep nature of cancer development. , 1984, Cancer research.

[51]  C. Pui,et al.  Lineage switch in acute leukemia. , 1984, Blood.

[52]  R. Bast,et al.  ANTI-B1 MONOCLONAL ANTIBODY AND COMPLEMENT TREATMENT IN AUTOLOGOUS BONE-MARROW TRANSPLANTATION FOR RELAPSED B-CELL NON-HODGKIN'S LYMPHOMA , 1984, The Lancet.

[53]  S. Korsmeyer,et al.  B cell origin of non-T cell acute lymphoblastic leukemia. A model for discrete stages of neoplastic and normal pre-B cell differentiation. , 1984, The Journal of clinical investigation.

[54]  J. Rowley.  Biological implications of consistent chromosome rearrangements in leukemia and lymphoma. , 1984, Cancer research.

[55]  Susan M. Watanabe,et al.  An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity , 1984, Cell.

[56]  P. Beverley.  Hybridomas, monoclonal cells and analysis of the immune system. , 1984, British medical bulletin.

[57]  G. Gaedicke,et al.  Enzyme markers in acute leukemias: advances during the last decade. , 1984, Journal of the National Cancer Institute.

[58]  G. Pinkus,et al.  Expression of human B cell-associated antigens on leukemias and lymphomas: a model of human B cell differentiation. , 1984, Blood.

[59]  S. Kvaløy,et al.  Transferrin receptor and B‐lymphoblast antigen — their relationship to DNA synthesis, histology and survival in B‐cell lymphomas , 1984, International journal of cancer.

[60]  H. E. Gray,et al.  Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation , 1984, Cell.

[61]  C. Mcgowan.  Evolutionary relationships of ratites and carinates: evidence from ontogeny of the tarsus , 1984, Nature.

[62]  A. Look,et al.  New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia , 1984, Cell.

[63]  R. Warnke,et al.  Immunoglobulin gene rearrangement as a diagnostic criterion of B-cell lymphoma. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[64]  K. Lennert,et al.  Immunohistological analysis of human lymphoma: correlation of histological and immunological categories. , 1984, Advances in cancer research.

[65]  R. Andreesen,et al.  A Hodgkin cell-specific antigen is expressed on a subset of auto- and alloactivated T (helper) lymphoblasts. , 1984, Blood.

[66]  L. Hood,et al.  The structure, rearrangement and expression of Dβ gene segments of the murine T-cell antigen receptor , 1984, Nature.

[67]  B. Haynes,et al.  Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[68]  P. Leder,et al.  Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor , 1983, Cell.

[69]  W. Herr,et al.  Monoclonal AKR/J thymic leukemias contain multiple JH immunoglobulin gene rearrangements. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[70]  D. G. Osmond,et al.  Pre-B cells in mouse bone marrow: immunofluorescence stathmokinetic studies of the proliferation of cytoplasmic mu-chain-bearing cells in normal mice. , 1983, Journal of immunology.

[71]  C. Taylor,et al.  Experimental models of lymphoproliferative disease. The mouse as a model for human non-Hodgkin's lymphomas and related leukemias. , 1983, The American journal of pathology.

[72]  U. Francke,et al.  The c-Ha-ras1, insulin and β-globin loci map outside the deletion associated with aniridia-Wilms' tumour , 1983, Nature.

[73]  T. Waldmann,et al.  Lymphoid blast crises of chronic myelogenous leukemia represent stages in the development of B-cell precursors. , 1983, The New England journal of medicine.

[74]  P. Leder,et al.  The human c-myc oncogene: Structural consequences of translocation into the igh locus in Burkitt lymphoma , 1983, Cell.

[75]  E. Henderson,et al.  Clonal chromosome abnormalities in patients with Waldenström's and CLL-associated macroglobulinemia: significance of trisomy 12. , 1983, Blood.

[76]  P. Bunn,et al.  Generation of an HLA-restricted cytotoxic T cell line reactive against cultured tumor cells from a patient infected with human T cell leukemia/lymphoma virus , 1983, The Journal of experimental medicine.

[77]  C. Y. Wang,et al.  Idiotype-like molecules on cells of a human T cell leukemia , 1983, The Journal of experimental medicine.

[78]  A. Sandberg,et al.  A possible subgroup of ALL with 9p-. , 1983, Cancer genetics and cytogenetics.

[79]  S. Hakomori,et al.  Glycosphingolipids as tumor-associated and differentiation markers. , 1983, Journal of the National Cancer Institute.

[80]  W. S. Hayward,et al.  Localization of c-ras oncogene family on human germ-line chromosomes. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[81]  B. Chiang,et al.  Insulin receptors on leukemia and lymphoma cells. , 1983, Blood.

[82]  J. Yunis.  The chromosomal basis of human neoplasia. , 1983, Science.

[83]  E. McCulloch.  Stem cells in normal and leukemic hemopoiesis (Henry Stratton Lecture, 1982) , 1983 .

[84]  R. Perry.  Consequences of myc invasion of immunoglobulin loci: Facts and speculation , 1983, Cell.

[85]  T. Waldmann,et al.  Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[86]  M. Abeloff,et al.  Analysis of cell surface proteins delineates a differentiation pathway linking endocrine and nonendocrine human lung cancers. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[87]  L. Smith,et al.  Lineage infidelity in acute leukemia. , 1983, Blood.

[88]  P. Edwards,et al.  Monoclonal antiglycophorin as a probe for erythroleukemias. , 1983, Blood.

[89]  T. Lister,et al.  CORRELATION OF TRANSFERRIN RECEPTOR EXPRESSION WITH HISTOLOGICAL CLASS AND OUTCOME IN NON-HODGKIN LYMPHOMA , 1983, The Lancet.

[90]  Jaffe Es.  Follicular lymphomas: possibility that they are benign tumors of the lymphoid system. , 1983 .

[91]  J. Habeshaw,et al.  The cellular content of non Hodgkin lymphomas: a comprehensive analysis using monoclonal antibodies and other surface marker techniques. , 1983, British Journal of Cancer.

[92]  R. Weinberg,et al.  Oncogene from human EJ bladder carcinoma is located on the short arm of chromosome 11. , 1983, Science.

[93]  G. Klein.  Specific chromosomal translocations and the genesis of B-cell-derived tumors in mice and men , 1983, Cell.

[94]  T. Waldmann,et al.  Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins. , 1983, The Journal of clinical investigation.

[95]  A. Michael,et al.  Stages of renal ontogenesis identified by monoclonal antibodies reactive with lymphohemopoietic differentiation antigens , 1983, The Journal of experimental medicine.

[96]  J. Ritz,et al.  Purification and characterization of fetal hematopoietic cells that express the common acute lymphoblastic leukemia antigen (CALLA) , 1983, The Journal of experimental medicine.

[97]  M. Greaves,et al.  Selective expression of the common acute lymphoblastic leukemia (gp 100) antigen on immature lymphoid cells and their malignant counterparts. , 1983, Blood.

[98]  R. Warnke,et al.  Identification and significance of cell markers in leukemia and lymphoma. , 1983, Annual review of medicine.

[99]  T. Lister,et al.  ALL masquerading as AUL. , 1983, Leukemia research.

[100]  M. Greaves,et al.  Chromosome assignment of monoclonal antibody‐defined determinants on human leukemic cells , 1983, European journal of immunology.

[101]  T. Lebien,et al.  CLINICAL USEFULNESS OF MONOCLONAL- ANTIBODY PHENOTYPING IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKAEMIA , 1982, The Lancet.

[102]  C. Croce,et al.  Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[103]  S. Korsmeyer,et al.  Induction of differentiation in a case of common acute lymphoblastic leukemia. , 1982, The New England journal of medicine.

[104]  V. Diehl,et al.  Identification of Hodgkin and sternberg‐reed cells as a unique cell type derived from a newly‐detected small‐cell population , 1982, International journal of cancer.

[105]  A. Look,et al.  Aneuploidy and percentage of S-phase cells determined by flow cytometry correlate with cell phenotype in childhood acute leukemia. , 1982, Blood.

[106]  M. Greaves,et al.  Changes in cell surface antigen expression during hemopoietic differentiation. , 1982, Blood.

[107]  R. Bast,et al.  AUTOLOGOUS BONE-MARROW TRANSPLANTATION IN CALLA-POSITIVE ACUTE LYMPHOBLASTIC LEUKAEMIA AFTER IN-VITRO TREATMENT WITH J5 MONOCLONAL ANTIBODY AND COMPLEMENT , 1982, The Lancet.

[108]  S. Hakomori,et al.  Carbohydrate chains specific for blood group antigens in differentiation of human oral epithelium. , 1982, The Journal of investigative dermatology.

[109]  M. Lipinski,et al.  A monoclonal antibody with anti‐burkitt lymphoma specificity. I. Analysis of human haematopoietic and lymphoid cell lines , 1982, International journal of cancer.

[110]  L. Zech,et al.  Cytogenetic mapping of the duplicated segment of chromosome 12 in lymphoproliferative disorders , 1982, Nature.

[111]  G. Gahrton,et al.  Chromosomal aberrations in chronic B-cell lymphocytic leukemia. , 1982, Cancer genetics and cytogenetics.

[112]  A. Tsiatis,et al.  Relationship of pretreatment lymphoblast proliferative activity and prognosis in 97 children with acute lymphoblastic leukemia. , 1982, Blood.

[113]  G. Holm,et al.  Idiotype-bearing lymphoid cells in plasma cell neoplasia. , 1982, Clinics in haematology.

[114]  M. Gobbi,et al.  Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia , 1982, The Journal of experimental medicine.

[115]  M. Greaves,et al.  Modulation of T leukaemic cell phenotype with phorbol ester , 1982, International journal of cancer.

[116]  M. Greaves,et al.  5'nucleotidase, adenosine deaminase and purine nucleoside phosphorylase activities in acute leukaemia. , 1982, Leukemia research.

[117]  J. Rowley,et al.  Chromosome abnormalities in malignant hematologic diseases. , 1982, Advances in cancer research.

[118]  M. Greaves,et al.  Monoclonal antibodies defining markers with apparent selectivity for particular haemopoietic cell types may also detect antigens on cells of neural crest origin. , 1982, Hybridoma.

[119]  T. Waldmann,et al.  Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[120]  E. Reinherz,et al.  Comparative expression of T9, T10, and Ia antigens on activated human T cell subsets. , 1981, Human immunology.

[121]  S. Sallan,et al.  Clinical utility of leukemia cell terminal transferase measurements. , 1981, Cancer research.

[122]  T. Mak,et al.  Induction of human malignant T‐lymphoblastic cell lines MOLT‐3 and jurkat by 12‐O‐tetradecanoylphorbol‐13‐acetate: Biochemical, physical, and morphological characterization , 1981, Journal of cellular physiology.

[123]  M. Borowitz,et al.  Distribution of common acute lymphoblastic leukemia antigen in nonhematopoietic tissues , 1981, The Journal of experimental medicine.

[124]  I. Magrath.  Lymphocyte differentiation: an essential basis for the comprehension of lymphoid neoplasia. , 1981, Journal of the National Cancer Institute.

[125]  G. Janossy,et al.  Delineation of human thymocyte differentiation pathways utilizing double-staining techniques with monoclonal antibodies. , 1981, Clinical and experimental immunology.

[126]  M. Greaves,et al.  Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[127]  A. Sandberg,et al.  Chromosomes and causation of human cancer and leukemia. XLV. Chromosome patterns in stimulated lymphocytes of chronic lymphocytic leukemia. , 1981, Cancer genetics and cytogenetics.

[128]  J. Peto,et al.  Immunologically Defined Subclasses of Acute Lymphoblastic Leukaemia in Children: their Relationship to Presentation Features and Prognosis , 1981, British journal of haematology.

[129]  D. Maloney,et al.  The use of a monoclonal anti-idiotype antibody to study the biology of a human B cell lymphoma. , 1981, Journal of immunology.

[130]  Koeffler Hp,et al.  Chronic myelogenous leukemia--new concepts (first of two parts). , 1981 .

[131]  S. Tonegawa,et al.  Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes , 1981, Nature.

[132]  E. Reinherz,et al.  The characterization and function of human immunoregulatory T lymphocyte subsets. , 1981, Immunology today.

[133]  M. Greaves,et al.  Isoenzyme profiles of lysosomal hydrolases in leukaemic cells. , 1981, Leukemia research.

[134]  M. Greaves,et al.  Expression of the OKT monoclonal antibody defined antigenic determinants in malignancy. , 1981, International journal of immunopharmacology.

[135]  S. Hakomori.  Glycosphingolipids in cellular interaction, differentiation, and oncogenesis. , 1981, Annual review of biochemistry.

[136]  M. Greaves,et al.  Phenotypic heterogeneity and cellular origins of T cell malignancies. , 1981, Leukemia research.

[137]  J. Till,et al.  Hemopoietic stem cell differentiation. , 1980, Biochimica et biophysica acta.

[138]  D. Huhn,et al.  Multimarker classification of acute lymphoblastic leukemia: evidence for further T subgroups and evaluation of their clinical significance. , 1980, Blood.

[139]  L. Sachs.  Constitutive uncoupling of pathways of gene expression that control growth and differentiation in myeloid leukemia: a model for the origin and progression of malignancy. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[140]  C. Milstein,et al.  Subpopulations of normal and leukemic human thymocytes: an analysis with the use of monoclonal antibodies. , 1980, Journal of the National Cancer Institute.

[141]  D. Kemp,et al.  Expression of the immunoglobulin C mu gene in mouse T and B lymphoid and myeloid cell lines. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[142]  D. Crowther,et al.  Relationship between the pretreatment proliferative activity of marrow blast cells and prognosis of acute lymphoblastic leukaemia of childhood , 1980, British Journal of Cancer.

[143]  Ellis L. Reinherz,et al.  The differentiation and function of human T lymphocytes , 1980, Cell.

[144]  E. Reinherz,et al.  Discrete stages of human intrathymic differentiation: analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[145]  R. Gelber,et al.  Cell surface antigens: prognostic implications in childhood acute lymphoblastic leukemia. , 1980, Blood.

[146]  I. Weissman,et al.  Production of alloreactive T-cell lymphomas , 1980, Nature.

[147]  M. Greaves,et al.  Acute lymphoblastic leukaemia associated antigen. IV. Expression on non-leukaemic 'lymphoid' cells. , 1980, Leukemia research.

[148]  Karl‐Henrik Robfert.  Induction of Monoclonal Antibody Synthesis in Malignant Human B Cells by Polyclonal B Cell Activators , 1979 .

[149]  F. Bollum.  Terminal deoxynucleotidyl transferase as a hematopoietic cell marker. , 1979, Blood.

[150]  Lukes Rj.  The immunologic approach to the pathology of malignant lymphomas. , 1979 .

[151]  H. Gleichmann,et al.  Immunoblastic lymphadenopathy, systemic lupus erythematosus, and related disorders. Possible pathogenetic pathways. , 1979, American journal of clinical pathology.

[152]  M. Greaves,et al.  Terminal transferase-positive human bone marrow cells exhibit the antigenic phenotype of common acute lymphoblastic leukemia. , 1979, Journal of immunology.

[153]  C. Bloomfield,et al.  Clinical utility of lymphocyte surface markers combined with the Lukes-Collins histologic classification in adult lymphoma. , 1979, The New England journal of medicine.

[154]  L. Lajtha.  Stem cell concepts. , 1979, Nouvelle revue francaise d'hematologie.

[155]  H. Kaplan,et al.  Induction, establishment in vitro, and characterization of functional, antigen-specific, carrier-primed murine T-cell lymphomas. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[156]  M. Greaves,et al.  Antigenic and enzymatic phenotypes of the pre-B subclass of acute lymphoblastic leukaemia. , 1979, Leukemia research.

[157]  L. Zech,et al.  A recurrent structural aberration, t(7;14), in phytohemagglutinin-stimulated lymphocytes. , 2009, Hereditas.

[158]  M. Greaves,et al.  Patterns of gene expression and the cellular origins of human leukaemias. , 1978, Biochimica et biophysica acta.

[159]  T. Graf,et al.  Temperature-sensitive mutant of avian erythroblastosis virus suggests a block of differentiation as mechanism of leukaemogenesis , 1978, Nature.

[160]  V. Potter.  Phenotypic diversity in experimental hepatomas: the concept of partially blocked ontogeny. The 10th Walter Hubert Lecture. , 1978, British Journal of Cancer.

[161]  R. Schwartz,et al.  Immunodeficiency and the pathogenesis of lymphoma and leukemia. , 1978, Seminars in hematology.

[162]  R. Levy,et al.  Immunopathology of follicular lymphomas. A model of B-lymphocyte homing. , 1978, The New England journal of medicine.

[163]  M. Greaves,et al.  ACUTE LYMPHOBLASTIC LEUKÆMIA IN CHILDREN: CLASSIFICATION AND PROGNOSIS , 1977, The Lancet.

[164]  R. Shields.  Gene derepression in tumours , 1977, Nature.

[165]  M. Lippman,et al.  Glucocorticoid receptors in subpopulations of childhood acute lymphocytic leukemia. , 1977, Cancer research.

[166]  T. Papayannopoulou,et al.  Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage. , 1977, The American journal of medicine.

[167]  B. Weintraub,et al.  Ectopic production of human chorionic gonadotropin and its subunits by islet cell tumors a specific marker for malignancy , 1977 .

[168]  P. Nowell.  The clonal evolution of tumor cell populations. , 1976, Science.

[169]  D. Hough,et al.  Anti-idiotype sera raised against surface immunoglobulin of human neoplastic lymphocytes , 1976, The Journal of experimental medicine.

[170]  L. Rees.  The biosynthesis of hormones by non-endocrine tumours--a review. , 1975, The Journal of endocrinology.

[171]  L. Borella,et al.  Clinical importance of lymphoblasts with T markers in childhood acute leukemia. , 1975, The New England journal of medicine.

[172]  D. Briles,et al.  IDIOTYPIC UNIFORMITY OF CELL SURFACE IMMUNOGLOBULIN IN CHRONIC LYMPHOCYTIC LEUKEMIA , 1974, The Journal of experimental medicine.

[173]  Pierce Gb.  Neoplasms, differentiations and mutations. , 1974 .

[174]  N. Anderson,et al.  Cancer, differentiation and embryonic antigens: some central problems. , 1974, Advances in cancer research.

[175]  A. Pearse,et al.  THE CYTOCHEMISTRY AND ULTRASTRUCTURE OF POLYPEPTIDE HORMONE-PRODUCING CELLS OF THE APUD SERIES AND THE EMBRYOLOGIC, PHYSIOLOGIC AND PATHOLOGIC IMPLICATIONS OF THE CONCEPT , 1969, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[176]  C. Markert.  Neoplasia: a disease of cell differentiation. , 1968, Cancer research.