Cefdinir is one of the third generation cephalosporins which have broad spectrum antibacterial activity. Cefdinir has activity against Gram-positive and Gram-negative bacteria. It is also effective against β-lactamase producing strains of haemophilis and neisseria. This drug is used to treat wide variety of sensitive bacteria infections, especially for mild and moderate infections [1]. To reduce the development of drug-resistant bacteria and maintain the effectiveness of cefdinir, it should be used only to treat or prevent infections that are proven or strongly suspected to be caused bacteria. Cefdinir capsule, tablet and suspension are available in the market for several years [2]. Now, cefdinir dispersible tablet is investegated to determine whether it is bioequivalent to other cefdinir preparations [3-5]. Cefdinir dispersible tablet disintegrates very fast and disperses homogenously, it is easily to be absorbed, and highly effective. The purpose of this study was to determine the pharmacokinetics and bioequivalence between cefdinir dispersible tablet (test preparation) and cefdinir capsule (reference preparation) and to ascertain the safety in medical practice.
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