Lipid droplet binding thalidomide analogs activate endoplasmic reticulum stress and suppress hepatocellular carcinoma in a chemically induced transgenic mouse model

[1]  L. Puskás,et al.  Lipid droplet binding thalidomide analogs activate endoplasmic reticulum stress and suppress hepatocellular carcinoma in a chemically induced transgenic mouse model , 2013, Lipids in Health and Disease.

[2]  L. Puskás,et al.  Combination of Small Molecule Microarray and Confocal Microscopy Techniques for Live Cell Staining Fluorescent Dye Discovery , 2013, Molecules.

[3]  Wan-ying Wu,et al.  Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90 , 2012, Journal of cellular physiology.

[4]  L. Puskás,et al.  The effect of sucrose esters on a culture model of the nasal barrier. , 2012, Toxicology in vitro : an international journal published in association with BIBRA.

[5]  W. Blaner,et al.  Diethylnitrosamine-induced hepatocarcinogenesis is suppressed in lecithin:retinol acyltransferase-deficient mice primarily through retinoid actions immediately after carcinogen administration. , 2012, Carcinogenesis.

[6]  Liliána Z Fehér,et al.  MicroRNA profile of polyunsaturated fatty acid treated glioma cells reveal apoptosis-specific expression changes , 2011, Lipids in Health and Disease.

[7]  L. Puskás,et al.  Removal of nonspecific binding proteins from cell and tissue extracts using 2-aminobenzimidazole-tethered affinity resin. , 2011, Die Pharmazie.

[8]  S. Ohta,et al.  Protein disulfide isomerase knockdown-induced cell death is cell-line-dependent and involves apoptosis in MCF-7 cells. , 2011, The Journal of toxicological sciences.

[9]  L. Puskás,et al.  Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells , 2010, Lipids in Health and Disease.

[10]  R. Schwabe,et al.  Hepatic stellate cell lipid droplets: a specialized lipid droplet for retinoid storage. , 2009, Biochimica et biophysica acta.

[11]  F. Trevisani,et al.  Recent advances in the natural history of hepatocellular carcinoma. , 2008, Carcinogenesis.

[12]  E. Chevet,et al.  Integrated endoplasmic reticulum stress responses in cancer. , 2007, Cancer research.

[13]  K. Gardner,et al.  Selective leukemic-cell killing by a novel functional class of thalidomide analogs. , 2006, Blood.

[14]  Xianlin Han,et al.  Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death Published, JLR Papers in Press, September 7, 2006. , 2006, Journal of Lipid Research.

[15]  B. Bell,et al.  The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide. , 2006, Journal of hepatology.

[16]  R. Kaufman,et al.  From acute ER stress to physiological roles of the Unfolded Protein Response , 2006, Cell Death and Differentiation.

[17]  J. Luk,et al.  Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat‐shock proteins (Hsp27, Hsp70, GRP78) up‐regulation and their associated prognostic values , 2006, Proteomics.

[18]  J. Chi,et al.  Expressions of HSP70 and HSP27 in Hepatocellular Carcinoma , 2005, Journal of Korean medical science.

[19]  Seung-Oe Lim,et al.  Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-related hepatocellular carcinomas and dysplastic nodules. , 2005, World journal of gastroenterology.

[20]  F. Deák,et al.  Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities. , 2004, Matrix biology : journal of the International Society for Matrix Biology.

[21]  S. Hirohashi,et al.  Expression profiling in multistage hepatocarcinogenesis: Identification of HSP70 as a molecular marker of early hepatocellular carcinoma , 2003, Hepatology.

[22]  R. Noiva Protein disulfide isomerase: the multifunctional redox chaperone of the endoplasmic reticulum. , 1999, Seminars in cell & developmental biology.

[23]  A. Holmgren,et al.  Protein disulfide-isomerase is a substrate for thioredoxin reductase and has thioredoxin-like activity. , 1990, The Journal of biological chemistry.

[24]  R. Freedman Protein disulfide isomerase: Multiple roles in the modification of nascent secretory proteins , 1989, Cell.

[25]  S. Goldfarb,et al.  Preneoplastic and neoplastic progression during hepatocarcinogenesis in mice injected with diethylnitrosamine in infancy. , 1983, Environmental health perspectives.

[26]  S. Iijima,et al.  PLACENTAL TRANSFER OF CHROMIC CHLORIDE AND ITS TERATOGENIC POTENTIAL IN EMBRYONIC MICE , 1976 .

[27]  L. Puskás,et al.  A cell-microelectronic sensing technique for the screening of cytoprotective compounds. , 2010, International journal of molecular medicine.

[28]  G. Gauglitz,et al.  Strategies for label-free optical detection. , 2008, Advances in biochemical engineering/biotechnology.

[29]  C. Arús,et al.  A possible cellular explanation for the NMR-visible mobile lipid (ML) changes in cultured C6 glioma cells with growth. , 2007, Biochimica et biophysica acta.

[30]  G. Williams,et al.  N-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation. , 1996, Pharmacology & therapeutics.

[31]  D. Woodfield Hepatocellular carcinoma. , 1986, The New Zealand medical journal.