Clinical Translation and Industrial Development of Microneedle-based Products

[1]  Thakur Raghu Raj Singh,et al.  Hydrogel-Forming Microneedle Arrays for Enhanced Transdermal Drug Delivery , 2012, Advanced functional materials.

[2]  K. Duffy,et al.  Facial allergic granulomatous reaction and systemic hypersensitivity associated with microneedle therapy for skin rejuvenation. , 2014, JAMA dermatology.

[3]  J. McElnay,et al.  Paediatricians’ opinions of microneedle-mediated monitoring: a key stage in the translation of microneedle technology from laboratory into clinical practice , 2015, Drug Delivery and Translational Research.

[4]  Ryan F. Donnelly,et al.  Hydrogel-Forming Microneedle Arrays Can Be Effectively Inserted in Skin by Self-Application: A Pilot Study Centred on Pharmacist Intervention and a Patient Information Leaflet , 2014, Pharmaceutical Research.

[5]  Ryan F Donnelly,et al.  Review of patents on microneedle applicators. , 2011, Recent patents on drug delivery & formulation.

[6]  Maelíosa T. C. McCrudden,et al.  Repeat application of microneedles does not alter skin appearance or barrier function and causes no measurable disturbance of serum biomarkers of infection, inflammation or immunity in mice in vivo , 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[7]  Thakur Raghu Raj Singh,et al.  Optical coherence tomography is a valuable tool in the study of the effects of microneedle geometry on skin penetration characteristics and in-skin dissolution. , 2010, Journal of controlled release : official journal of the Controlled Release Society.

[8]  M. Allen,et al.  Microfabricated microneedles: a novel approach to transdermal drug delivery. , 1998, Journal of pharmaceutical sciences.

[9]  Y. Demir,et al.  Characterization of Polymeric Microneedle Arrays for Transdermal Drug Delivery , 2013, PloS one.

[10]  Ryan F. Donnelly,et al.  Successful application of large microneedle patches by human volunteers , 2017, International journal of pharmaceutics.

[11]  Conor O'Mahony,et al.  In-vivo dynamic characterization of microneedle skin penetration using optical coherence tomography. , 2010, Journal of biomedical optics.

[12]  J. McElnay,et al.  Children's views on microneedle use as an alternative to blood sampling for patient monitoring , 2014, The International journal of pharmacy practice.

[13]  Ryan F. Donnelly,et al.  Design and physicochemical characterisation of novel dissolving polymeric microneedle arrays for transdermal delivery of high dose, low molecular weight drugs , 2014, Journal of controlled release : official journal of the Controlled Release Society.

[14]  F. Rossetti,et al.  Microneedle-based drug delivery systems for transdermal route. , 2014, Current drug targets.

[15]  Ryan F. Donnelly,et al.  Hydrogel-Forming Microneedles Prepared from “Super Swelling” Polymers Combined with Lyophilised Wafers for Transdermal Drug Delivery , 2014, PloS one.

[16]  Ryan F Donnelly,et al.  Dissolving polymeric microneedle arrays for electrically assisted transdermal drug delivery. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[17]  R. Compans,et al.  Targeting the skin for microneedle delivery of influenza vaccine. , 2013, Advances in experimental medicine and biology.

[18]  Mark R Prausnitz,et al.  Microneedle patches: usability and acceptability for self-vaccination against influenza. , 2014, Vaccine.

[19]  A. Y. Chow,et al.  Implantation of silicon chip microphotodiode arrays into the cat subretinal space , 2001, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[20]  Jung-Hwan Park,et al.  Analysis of Mechanical Failure of Polymer Microneedles by Axial Force. , 2010, The journal of the Korean Physical Society.

[21]  L. Hanna,et al.  The Use of a Pressure-Indicating Sensor Film to Provide Feedback upon Hydrogel-Forming Microneedle Array Self-Application In Vivo , 2016, Pharmaceutical Research.

[22]  K. Horch,et al.  Biocompatibility of silicon-based electrode arrays implanted in feline cortical tissue. , 1993, Journal of biomedical materials research.

[23]  M. Garland,et al.  Laser-Engineered Dissolving Microneedle Arrays for Transdermal Macromolecular Drug Delivery , 2011, Pharmaceutical Research.

[24]  Ryan F. Donnelly,et al.  Microneedle Arrays Allow Lower Microbial Penetration Than Hypodermic Needles In Vitro , 2009, Pharmaceutical Research.

[25]  M. Kendall,et al.  Targeted, needle-free vaccinations in skin using multilayered, densely-packed dissolving microprojection arrays. , 2010, Small.

[26]  Conor O'Mahony,et al.  Processing difficulties and instability of carbohydrate microneedle arrays , 2009, Drug development and industrial pharmacy.

[27]  Tianwei Yu,et al.  The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial , 2017, The Lancet.

[28]  Ryan F. Donnelly,et al.  Skin Dendritic Cell Targeting via Microneedle Arrays Laden with Antigen-Encapsulated Poly-d,l-lactide-co-Glycolide Nanoparticles Induces Efficient Antitumor and Antiviral Immune Responses , 2013, ACS nano.

[29]  Maelíosa T. C. McCrudden,et al.  Strategies for enhanced peptide and protein delivery. , 2013, Therapeutic delivery.

[30]  Rebecca S. Shawgo,et al.  Biocompatibility and biofouling of MEMS drug delivery devices. , 2003, Biomaterials.