Localized Proton Magnetic Resonance Spectroscopy of Cerebral Metabolites

Recent advances in magnetic resonance technology have expanded the range of applications in neuropdatrics from structural imaging to metabolite spectroscopy. In particular, localized proton magnetic resonance spectroscopy (MRS) opens unique and truly noninvasive windows into human brain metabolism under both physiological and pathological conditions. So far, our personal experience is based on more than 400 iMRS examinations of over 300 cMdren mostly with neurometabolic, neurodegenerative, and neuroinflammatory disorders as summarized in Table 1.

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