Effects of hydroxyapatite content on mechanical properties and in-vitro corrosion behavior of ZK60/HA composites

Abstract In this study, hydroxyapatite-reinforced ZK60 Mg alloybased composites were fabricated via a powder metallurgy route. The mechanical properties of these composites were studied by compressive tests and hardness tests. The in-vitro corrosion behavior was also investigated using immersion testing and electrochemical measurement. The influence of hydroxyapatite content on the mechanical properties and invitro corrosion behavior was evaluated. The microstructure and corrosion morphology were characterized by means of X-ray diffraction, optical and scanning electron microscopy. The results showed that the composite materials with 10 wt.% hydroxyapatite exhibited a better combination of mechanical strength and corrosion resistance. Compared with ZK60 alloy, the addition of 10 wt.% hydroxyapatite resulted in an increase in corrosion resistance by 38.6%.

[1]  Yufeng Zheng,et al.  Fundamental Theory of Biodegradable Metals—Definition, Criteria, and Design , 2019, Advanced Functional Materials.

[2]  Yufeng Zheng,et al.  In vitro and in vivo investigation on biodegradable Mg-Li-Ca alloys for bone implant application , 2018, Science China Materials.

[3]  Jason L Guo,et al.  Material Processing and Design of Biodegradable Metal Matrix Composites for Biomedical Applications , 2018, Annals of Biomedical Engineering.

[4]  B. Liu,et al.  In vitro corrosion of magnesium alloy AZ31 — a synergetic influence of glucose and Tris , 2018, Frontiers of Materials Science.

[5]  P. Roy,et al.  Mechanical, corrosion and biocompatibility behaviour of Mg-3Zn-HA biodegradable composites for orthopaedic fixture accessories. , 2018, Journal of the mechanical behavior of biomedical materials.

[6]  E. Han,et al.  In vitro corrosion of Mg–Ca alloy — The influence of glucose content , 2017, Frontiers of Materials Science.

[7]  C. Shuai,et al.  Biodegradation Resistance and Bioactivity of Hydroxyapatite Enhanced Mg-Zn Composites via Selective Laser Melting , 2017, Materials.

[8]  B. Bhushan,et al.  Strengthening of Mg based alloy through grain refinement for orthopaedic application. , 2016, Journal of the mechanical behavior of biomedical materials.

[9]  E. Han,et al.  In vitro corrosion of as-extruded Mg–Ca alloys—The influence of Ca concentration , 2015 .

[10]  C Ganapathy,et al.  Processing and mechanical behavior of lamellar structured degradable magnesium-hydroxyapatite implants. , 2014, Journal of the mechanical behavior of biomedical materials.

[11]  Zhigang Xu,et al.  Recent advances on the development of magnesium alloys for biodegradable implants. , 2014, Acta biomaterialia.

[12]  A. Muñoz,et al.  Mechanical properties and corrosion behavior of Mg-HAP composites. , 2014, Journal of the mechanical behavior of biomedical materials.

[13]  Tong Cui,et al.  Development and evaluation of a magnesium-zinc-strontium alloy for biomedical applications--alloy processing, microstructure, mechanical properties, and biodegradation. , 2013, Materials science & engineering. C, Materials for biological applications.

[14]  T. Lei,et al.  Effects of Zn on microstructure, mechanical properties and corrosion behavior of Mg-Zn alloys , 2012 .

[15]  Diego Mantovani,et al.  Biodegradable Metals for Cardiovascular Stent Application: Interests and New Opportunities , 2011, International journal of molecular sciences.

[16]  Yong Han,et al.  Mechanical and in vitro degradation behavior of ultrafine calcium polyphosphate reinforced magnesium-alloy composites , 2011 .

[17]  Meng Yang,et al.  In vitro corrosion resistance and cytocompatibility of nano-hydroxyapatite reinforced Mg–Zn–Zr composites , 2010, Journal of materials science. Materials in medicine.

[18]  Yufeng Zheng,et al.  In vitro corrosion and biocompatibility of binary magnesium alloys. , 2009, Biomaterials.

[19]  M. Störmer,et al.  Biodegradable magnesium-hydroxyapatite metal matrix composites. , 2007, Biomaterials.

[20]  Guang-Ling Song,et al.  Control of biodegradation of biocompatable magnesium alloys , 2007 .

[21]  Tadashi Kokubo,et al.  How useful is SBF in predicting in vivo bone bioactivity? , 2006, Biomaterials.

[22]  Alexis M Pietak,et al.  Magnesium and its alloys as orthopedic biomaterials: a review. , 2006, Biomaterials.

[23]  S. R. Biaggio,et al.  Electrochemical studies on zirconium and its biocompatible alloys Ti-50Zr at.% and Zr-2.5Nb wt.% in simulated physiologic media. , 2005, Journal of biomedical materials research. Part A.

[24]  G. Song.  Recent Progress in Corrosion and Protection of Magnesium Alloys , 2005 .

[25]  Takashi Nakamura,et al.  Process and kinetics of bonelike apatite formation on sintered hydroxyapatite in a simulated body fluid. , 2005, Biomaterials.

[26]  D. StJohn,et al.  Corrosion resistance of aged die cast magnesium alloy AZ91D , 2004 .