A novel PPAR gamma gene therapy to control inflammation associated with inflammatory bowel disease in a murine model.
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S. Nakagawa | T. Mayumi | H. Mizuguchi | T. Hayakawa | T. Kadowaki | A. Nakajima | R. Nagai | K. Katayama | R. Blumberg | K. Wada | Y. Kamisaki
[1] W. Wahli,et al. Peroxisome Proliferator Activated Receptors , 2005 .
[2] H. Aburatani,et al. Peroxisome Proliferator-Activated Receptor Gamma Agonist Ligands Stimulate a Th2 Cytokine Response and Prevent Acute Colitis , 2002, Inflammatory bowel diseases.
[3] J. Miyazaki,et al. IL-15-Dependent Activation-Induced Cell Death-Resistant Th1 Type CD8αβ+NK1.1+ T Cells for the Development of Small Intestinal Inflammation1 , 2002, The Journal of Immunology.
[4] J. Stephens,et al. Interferon-γ-mediated Activation and Ubiquitin-Proteasome-dependent Degradation of PPARγ in Adipocytes* , 2002, The Journal of Biological Chemistry.
[5] A. Nakajima,et al. PPARγ and inflammatory bowel disease: a new therapeutic target for ulcerative colitis and Crohn's disease , 2001 .
[6] M. Kay,et al. A simplified system for constructing recombinant adenoviral vectors containing heterologous peptides in the HI loop of their fiber knob , 2001, Gene Therapy.
[7] J. Auwerx,et al. Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer , 2001, The Journal of experimental medicine.
[8] T. Mayumi,et al. Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors. , 2001, Biochemical and biophysical research communications.
[9] Judy H. Cho,et al. Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. , 2001, The Journal of clinical investigation.
[10] R. Blumberg,et al. Prospects for research in inflammatory bowel disease. , 2001, JAMA.
[11] Y. Terauchi,et al. Endogenous PPARγ mediates anti-inflammatory activity in murine ischemia-reperfusion injury , 2001 .
[12] F. Shanahan,et al. Inflammatory bowel disease: immunodiagnostics, immunotherapeutics, and ecotherapeutics. , 2001, Gastroenterology.
[13] R. Evans,et al. PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation , 2001, Nature Medicine.
[14] S. Snapper,et al. Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice. , 2000, Gastroenterology.
[15] Sander Kersten,et al. Roles of PPARs in health and disease , 2000, Nature.
[16] C. Glass,et al. 15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[17] W. Wahli,et al. Peroxisome proliferator-activated receptors: three isotypes for a multitude of functions. , 1999, Current opinion in biotechnology.
[18] M. Akens,et al. Quantitative Real-Time PCR for Equine Cytokine mRNA in Nondecalcified Bone Tissue Embedded in Methyl Methacrylate , 1999, Calcified Tissue International.
[19] Satoshi Tanaka,et al. PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance , 1999 .
[20] M. Lazar,et al. A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response. , 1999, The Journal of clinical investigation.
[21] M. Kay,et al. A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors. , 1999, Human gene therapy.
[22] J. Vamecq,et al. Medical significance of peroxisome proliferator-activated receptors , 1999, The Lancet.
[23] S. Mordon,et al. Endoscopic fluorescence imaging for the study of anastomotic recurrences in Crohn's disease (CD) correlation with histological findings , 1999 .
[24] M. Kay,et al. Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method. , 1998, Human gene therapy.
[25] J. G. Alvarez,et al. Activators of the nuclear receptor PPARγ enhance colon polyp formation , 1998, Nature Medicine.
[26] I. Singer,et al. Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease. , 1998, Gastroenterology.
[27] W. Wahli,et al. Printed in U.S.A. Copyright © 1998 by The Endocrine Society Differential Expression of Peroxisome Proliferator- Activated Receptor-�,-�, and- � during Rat , 2022 .
[28] O. Nielsen,et al. Expression of cyclooxygenase-2 mRNA in active inflammatory bowel disease. , 1997, The American journal of gastroenterology.
[29] K. Stecker,et al. An ICAM-1 antisense oligonucleotide prevents and reverses dextran sulfate sodium-induced colitis in mice. , 1997, The Journal of pharmacology and experimental therapeutics.
[30] B. Spiegelman,et al. Adipogenesis and Obesity: Rounding Out the Big Picture , 1996, Cell.
[31] B. Spiegelman,et al. 15-Deoxy-Δ 12,14-Prostaglandin J 2 is a ligand for the adipocyte determination factor PPARγ , 1995, Cell.
[32] F. Graham,et al. The use of adenoviral vectors for gene therapy and gene transfer in vivo. , 1995, Current opinion in biotechnology.
[33] A. Laupacis,et al. Low-dose cyclosporine for the treatment of Crohn's disease. The Canadian Crohn's Relapse Prevention Trial Investigators. , 1994, The New England journal of medicine.
[34] Y. Kanegae,et al. A simple and efficient method for purification of infectious recombinant adenovirus. , 1994, Japanese journal of medical science & biology.