Chemical synthesis of (3-SO3Na)GlcNAcβl-3Fucβl-OMe: The oligosaccharide involved in the cell aggregation of the sponge microciona prolifera

ABSTRACT The methyl glycoside, (3-SO3Na)GlcNAcβ1→3Fucβ1→OMe, of a sulfated disaccharide that is involved in the species-specific reaggregation of dissociated cells of Microciona prolifera, was stereoselectively synthesized starting from L-fucose and 2-amino-2-deoxy-D-glucose.

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