Non-secretory multiple myeloma with unusual TFG-ALK fusion showed dramatic response to ALK inhibition

[1]  S. Turner,et al.  The Transcriptional Roles of ALK Fusion Proteins in Tumorigenesis , 2019, Cancers.

[2]  H. Goldschmidt,et al.  Germline Risk Contribution to Genomic Instability in Multiple Myeloma , 2019, Front. Genet..

[3]  A. Shaw,et al.  Lorlatinib in patients with ALK-positive non-small-cell lung cancer: results from a global phase 2 study. , 2018, The Lancet. Oncology.

[4]  S. Benz,et al.  Comprehensive genomic transcriptomic tumor-normal gene panel analysis for enhanced precision in patients with lung cancer , 2018, Oncotarget.

[5]  O. Stephens,et al.  Kinase domain activation through gene rearrangement in multiple myeloma , 2018, Leukemia.

[6]  David M. Jones,et al.  ALK Fusions in a Wide Variety of Tumor Types Respond to Anti-ALK Targeted Therapy. , 2017, The oncologist.

[7]  R. Cho,et al.  Multiple Hereditary Infundibulocystic Basal Cell Carcinoma Syndrome Associated With a Germline SUFU Mutation. , 2016, JAMA dermatology.

[8]  Nam Huh,et al.  Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination , 2015, Proceedings of the National Academy of Sciences.

[9]  Nam Huh,et al.  Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway , 2015, Nature Genetics.

[10]  R. Pirker,et al.  Alectinib in RET-rearranged non-small cell lung cancer-Another progress in precision medicine? , 2015, Translational lung cancer research.

[11]  T. Chevassut,et al.  The Genetic Architecture of Multiple Myeloma , 2014, Advances in hematology.

[12]  Jeffrey A. Engelman,et al.  Tyrosine kinase gene rearrangements in epithelial malignancies , 2013, Nature Reviews Cancer.

[13]  J. Carpten,et al.  Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides. , 2012, Blood.

[14]  Zhigui Ma,et al.  ALK-positive extramedullary plasmacytoma with expression of the CLTC-ALK fusion transcript. , 2011, Pathology, research and practice.

[15]  Colin N. Dewey,et al.  RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome , 2011, BMC Bioinformatics.

[16]  Richard Durbin,et al.  Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .

[17]  Cole Trapnell,et al.  Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.

[18]  M. Cogné,et al.  Immunologic basis for the rare occurrence of true nonsecretory plasma cell dyscrasias , 2004, Journal of leukocyte biology.

[19]  A. Rosenwald,et al.  TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations. , 1999, Blood.

[20]  Terry M Therneau,et al.  Review of 1027 patients with newly diagnosed multiple myeloma. , 2003, Mayo Clinic proceedings.