Transcription factor Sp1 and oncoprotein PPP1R13L regulate nicotine-induced epithelial-mesenchymal transition in lung adenocarcinoma via a feedback loop.

[1]  Yongqi Huang,et al.  Leveraging the multivalent p53 peptide-MdmX interaction to guide the improvement of small molecule inhibitors , 2022, Nature Communications.

[2]  Yi-Ching Wang,et al.  Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression , 2022, Journal of biomedical science.

[3]  Guopei Zhang,et al.  Malignant transformation of human bronchial epithelial cells induced by benzo [a] pyrene suggests a negative feedback of TP53 to PPP1R13L via binding a possible enhancer element. , 2021, Chemico-biological interactions.

[4]  S. Gygi,et al.  Temporal proteomic changes induced by nicotine in human cells: A quantitative proteomics approach. , 2021, Journal of proteomics.

[5]  K. Pinkerton,et al.  MARCKS cooperates with NKAP to activate NF-kB signaling in smoke-related lung cancer , 2021, Theranostics.

[6]  O. Witkowska-Piłaszewicz,et al.  Role of Cadherins in Cancer—A Review , 2020, International journal of molecular sciences.

[7]  Xiaoli Ma,et al.  α5‐nAChR contributes to epithelial‐mesenchymal transition and metastasis by regulating Jab1/Csn5 signalling in lung cancer , 2020, Journal of cellular and molecular medicine.

[8]  K. Lamberg,et al.  Clinical characteristics and survival in non-small cell lung cancer patients by smoking history: a population-based cohort study , 2019, Acta oncologica.

[9]  J. Molina,et al.  Non-Small Cell Lung Cancer: Epidemiology, Screening, Diagnosis, and Treatment. , 2019, Mayo Clinic proceedings.

[10]  C. Blanpain,et al.  EMT Transition States during Tumor Progression and Metastasis. , 2019, Trends in cell biology.

[11]  Xiaowu Xu,et al.  Nicotine downregulates microRNA‐200c to promote metastasis and the epithelial–mesenchymal transition in human colorectal cancer cells , 2018, Journal of cellular physiology.

[12]  S. Chellappan,et al.  Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer , 2018, Molecular Cancer.

[13]  W. Rom,et al.  Aldehydes are the predominant forces inducing DNA damage and inhibiting DNA repair in tobacco smoke carcinogenesis , 2018, Proceedings of the National Academy of Sciences.

[14]  Mengqi Guo,et al.  Sp1 Plays an Important Role in Vascular Calcification Both In Vivo and In Vitro , 2018, Journal of the American Heart Association.

[15]  Chi‐Huey Wong,et al.  2‐anilino‐4‐amino‐5‐aroylthiazole‐type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction , 2018, Cancer science.

[16]  Roy S. Herbst,et al.  The biology and management of non-small cell lung cancer , 2018, Nature.

[17]  Mohini Singh,et al.  EMT: Mechanisms and therapeutic implications , 2017, Pharmacology & therapeutics.

[18]  Kunming Zhao,et al.  iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding. , 2017, Cancer cell.

[19]  Yingyu Chen,et al.  iASPP facilitates tumor growth by promoting mTOR-dependent autophagy in human non-small-cell lung cancer , 2017, Cell Death and Disease.

[20]  P. Dong,et al.  iASPP induces EMT and cisplatin resistance in human cervical cancer through miR-20a-FBXL5/BTG3 signaling , 2017, Journal of experimental & clinical cancer research : CR.

[21]  José Portugal,et al.  Sp1 transcription factor: A long-standing target in cancer chemotherapy. , 2015, Pharmacology & therapeutics.

[22]  G. Bepler,et al.  β-arrestin-1 mediates nicotine-induced metastasis through E2F1 target genes that modulate epithelial-mesenchymal transition. , 2015, Cancer research.

[23]  J. Azizkhan-Clifford,et al.  Sp1 and the ‘hallmarks of cancer’ , 2015, The FEBS journal.

[24]  N. Ramnath,et al.  Effects of Cigarette Smoking on Metabolism and Effectiveness of Systemic Therapy for Lung Cancer , 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[25]  S. Grando,et al.  Connections of nicotine to cancer , 2014, Nature Reviews Cancer.

[26]  Samy Lamouille,et al.  Molecular mechanisms of epithelial–mesenchymal transition , 2014, Nature Reviews Molecular Cell Biology.

[27]  S. Chellappan,et al.  Nicotine-Mediated Cell Proliferation and Tumor Progression in Smoking-Related Cancers , 2014, Molecular Cancer Research.

[28]  Haitao Luo,et al.  Nicotine Induces the Up-regulation of the α7-Nicotinic Receptor (α7-nAChR) in Human Squamous Cell Lung Cancer Cells via the Sp1/GATA Protein Pathway , 2013, The Journal of Biological Chemistry.

[29]  Q. Rao,et al.  [Effects of transcription factor GATA-2 on transcriptive regulation of iASPP gene]. , 2013, Zhongguo shi yan xue ye xue za zhi.

[30]  S. Chu Transcriptional regulation by post-transcriptional modification--role of phosphorylation in Sp1 transcriptional activity. , 2012, Gene.

[31]  W. Su,et al.  Sp1 expression regulates lung tumor progression , 2011, Oncogene.

[32]  K. Okumura,et al.  GATA2 and Sp1 Positively Regulate the c-kit Promoter in Mast Cells , 2010, The Journal of Immunology.

[33]  M. Carless,et al.  Nicotine induces cell proliferation, invasion and epithelial‐mesenchymal transition in a variety of human cancer cell lines , 2009, International journal of cancer.

[34]  Y. Maehara,et al.  Impact of Smoking Status on the Biological Behavior of Lung Cancer , 2007, Surgery Today.

[35]  Stephen S. Hecht,et al.  Tobacco carcinogens, their biomarkers and tobacco-induced cancer , 2003, Nature Reviews Cancer.

[36]  Tim Crook,et al.  iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human , 2003, Nature Genetics.

[37]  H. Okamoto,et al.  RelA-Associated Inhibitor Blocks Transcription of Human Immunodeficiency Virus Type 1 by Inhibiting NF-κB and Sp1 Actions , 2002, Journal of Virology.

[38]  K. Jensen,et al.  Cloning and Characterization of the 5′-Flanking Region of the Human Transcription Factor Sp1 Gene* , 2001, The Journal of Biological Chemistry.

[39]  P. Tsao,et al.  Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis , 2001, Nature Medicine.

[40]  W. Min,et al.  Functional Analysis of the Human Endothelial Nitric Oxide Synthase Promoter , 1995, The Journal of Biological Chemistry.