Bovine tumor necrosis factor-alpha Increases IL-6, IL-8, and PGE2 in bovine fibroblast-like synoviocytes by metabolic reprogramming

[1]  Lucas B. Sullivan,et al.  A non-canonical tricarboxylic acid cycle underlies cellular identity , 2022, Nature.

[2]  T. Gaber,et al.  Metabolic reprogramming of synovial fibroblasts in osteoarthritis by inhibition of pathologically overexpressed pyruvate dehydrogenase kinases. , 2022, Metabolic engineering.

[3]  Wei Wang,et al.  Epigenetic Regulation of Nutrient Transporters in Rheumatoid Arthritis Fibroblast‐like Synoviocytes , 2022, Arthritis & rheumatology.

[4]  C. Manosalva,et al.  Role of Lactate in Inflammatory Processes: Friend or Foe , 2022, Frontiers in Immunology.

[5]  M. Herrmann,et al.  TNF induces glycolytic shift in fibroblast like synoviocytes via GLUT1 and HIF1A , 2021, Scientific Reports.

[6]  Hongjun Li,et al.  Influences of the lncRNA TUG1‐miRNA‐34a‐5p network on fibroblast‐like synoviocytes (FLSs) dysfunction in rheumatoid arthritis through targeting the lactate dehydrogenase A (LDHA) , 2021, Journal of clinical laboratory analysis.

[7]  A. Islam,et al.  Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy. , 2021, Biochimica et biophysica acta. Reviews on cancer.

[8]  C. Manosalva,et al.  Metabolic Reprogramming and Inflammatory Response Induced by D-Lactate in Bovine Fibroblast-Like Synoviocytes Depends on HIF-1 Activity , 2021, Frontiers in Veterinary Science.

[9]  A. Rudensky,et al.  Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity , 2020, Science.

[10]  J. Coetzee,et al.  Randomized controlled trial comparison of analgesic drugs for control of pain associated with induced lameness in lactating dairy cattle. , 2020, Journal of dairy science.

[11]  C. Manosalva,et al.  D-Lactate Increases Cytokine Production in Bovine Fibroblast-Like Synoviocytes via MCT1 Uptake and the MAPK, PI3K/Akt, and NFκB Pathways , 2020, Animals : an open access journal from MDPI.

[12]  M. Masoumi,et al.  Role of glucose metabolism in aggressive phenotype of fibroblast-like synoviocytes: Latest evidence and therapeutic approaches in rheumatoid arthritis. , 2020, International immunopharmacology.

[13]  Guangjie Chen,et al.  Hypoxia-Inducible Factor Is Critical for Pathogenesis and Regulation of Immune Cell Functions in Rheumatoid Arthritis , 2020, Frontiers in Immunology.

[14]  M. Kriegsmann,et al.  Proinflammatory profile of autoimmune CD8+ T cells relies on increased LDHA activity and aerobic glycolysis. , 2020, Arthritis & rheumatology.

[15]  C. Limatola,et al.  Metabolic Reprograming of Microglia in the Regulation of the Innate Inflammatory Response , 2020, Frontiers in Immunology.

[16]  D. Veale,et al.  Targeting bioenergetics prevents CD4 T cell-mediated activation of synovial fibroblasts in rheumatoid arthritis. , 2020, Rheumatology.

[17]  C. Cao,et al.  PI3K/Akt inhibitor partly decreases TNF-α-induced activation of fibroblast-like synoviocytes in osteoarthritis , 2019, Journal of Orthopaedic Surgery and Research.

[18]  K. Terabe,et al.  Chondroprotective effects of 4-methylumbelliferone and hyaluronan synthase-2 overexpression involve changes in chondrocyte energy metabolism , 2019, The Journal of Biological Chemistry.

[19]  Wei Zhu,et al.  A Novel Phytochemical, DIM, Inhibits Proliferation, Migration, Invasion and TNF-α Induced Inflammatory Cytokine Production of Synovial Fibroblasts From Rheumatoid Arthritis Patients by Targeting MAPK and AKT/mTOR Signal Pathway , 2019, Front. Immunol..

[20]  T. Kaehne,et al.  Pro-inflammatory mediators and neutrophils are increased in synovial fluid from heifers with acute ruminal acidosis , 2019, BMC Veterinary Research.

[21]  L. Ivashkiv,et al.  TNF-induced inflammatory genes escape repression in fibroblast-like synoviocytes: transcriptomic and epigenomic analysis , 2019, Annals of the rheumatic diseases.

[22]  Cheng-yu Wang,et al.  Effects of silymarin on p65 NF-κB, p38 MAPK and CYP450 in LPS-induced hoof dermal inflammatory cells of dairy cows , 2019, BMC Veterinary Research.

[23]  C. Manosalva,et al.  Metabolic disturbances in synovial fluid are involved in the onset of synovitis in heifers with acute ruminal acidosis , 2019, Scientific Reports.

[24]  K. Sheng,et al.  PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia , 2018, Molecular medicine reports.

[25]  Young-Jun Kim,et al.  Inhibition of lactate dehydrogenase A suppresses inflammatory response in RAW 264.7 macrophages. , 2018, Molecular medicine reports.

[26]  G. Firestein,et al.  Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis , 2018, Annals of the rheumatic diseases.

[27]  Michael J. Dagley,et al.  DExSI: a new tool for the rapid quantitation of 13C-labelled metabolites detected by GC-MS , 2018, Bioinform..

[28]  D. Piccolo,et al.  Synovial Fluid and Serum Concentrations of Inflammatory Markers in Rheumatoid Arthritis, Psoriatic Arthritis and Osteoarthitis: A Systematic Review. , 2017, Current rheumatology reviews.

[29]  C. Corbet,et al.  Cancer cell metabolism and mitochondria: Nutrient plasticity for TCA cycle fueling. , 2017, Biochimica et biophysica acta. Reviews on cancer.

[30]  G. Ateshian,et al.  Fibroblast-like synoviocyte mechanosensitivity to fluid shear is modulated by interleukin-1α. , 2017, Journal of biomechanics.

[31]  M. Guma,et al.  Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis , 2017, Arthritis Research & Therapy.

[32]  Z. Zhan,et al.  Inhibition of 6‐phosphofructo‐2‐kinase suppresses fibroblast‐like synoviocytes‐mediated synovial inflammation and joint destruction in rheumatoid arthritis , 2017, British journal of pharmacology.

[33]  A. Morinobu,et al.  Glutaminase 1 plays a key role in the cell growth of fibroblast-like synoviocytes in rheumatoid arthritis , 2017, Arthritis Research & Therapy.

[34]  U. Chandrasekharan,et al.  The joint synovium: A critical determinant of articular cartilage fate in inflammatory joint diseases. , 2017, Seminars in cell & developmental biology.

[35]  C. Pitzalis,et al.  Lactate at the crossroads of metabolism, inflammation, and autoimmunity , 2017, European journal of immunology.

[36]  M. Recanatini,et al.  Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells , 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[37]  J. Ryan,et al.  Dysregulated bioenergetics: a key regulator of joint inflammation , 2016, Annals of the rheumatic diseases.

[38]  C. Benelli,et al.  The pyruvate dehydrogenase complex in cancer: An old metabolic gatekeeper regulated by new pathways and pharmacological agents , 2016, International journal of cancer.

[39]  E. Cummins,et al.  The role of HIF in immunity and inflammation. , 2016, Molecular aspects of medicine.

[40]  K. Kim,et al.  Metabolomic Elucidation of the Effects of Curcumin on Fibroblast-Like Synoviocytes in Rheumatoid Arthritis , 2015, PloS one.

[41]  Sean C. Sapcariu,et al.  Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression , 2015, The Journal of Biological Chemistry.

[42]  D. Hailemariam,et al.  Alterations of Innate Immunity Reactants in Transition Dairy Cows before Clinical Signs of Lameness , 2015, Animals : an open access journal from MDPI.

[43]  Eleanor C. Saunders,et al.  Use of (13)C stable isotope labelling for pathway and metabolic flux analysis in Leishmania parasites. , 2015, Methods in molecular biology.

[44]  H. Buimer,et al.  No . 26 BUSINESS DEVELOPMENT THROUHG NETWORKING AN EXPLORATIVE STUDY By : Olav Jull Sørensen , 2001 .

[45]  K. Frankena,et al.  A descriptive review of the prevalence and risk factors of hock lesions in dairy cows. , 2014, Veterinary journal.

[46]  A. Desrochers,et al.  Clinical management of septic arthritis in cattle. , 2014, The Veterinary clinics of North America. Food animal practice.

[47]  B. Johansen,et al.  Cytosolic Phospholipase A2 Regulates TNF-Induced Production of Joint Destructive Effectors in Synoviocytes , 2013, PloS one.

[48]  E. Morand,et al.  Fibroblasts and synovial immunity. , 2013, Current opinion in pharmacology.

[49]  N. Bottini,et al.  Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors , 2013, Nature Reviews Rheumatology.

[50]  N. Saidenberg-Kermanac’h,et al.  Rheumatoid arthritis: from autoimmunity to synovitis and joint destruction. , 2012, Journal of autoimmunity.

[51]  M. Haghkhah,et al.  Acute phase response in lame cattle with interdigital dermatitis , 2012, World journal of microbiology & biotechnology.

[52]  G. Semenza,et al.  Hypoxia-Inducible Factors in Physiology and Medicine , 2012, Cell.

[53]  E. Mohammadi,et al.  Barriers and facilitators related to the implementation of a physiological track and trigger system: A systematic review of the qualitative evidence , 2017, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[54]  Malcolm D. Smith.  The Normal Synovium , 2011, The open rheumatology journal.

[55]  J. O’Sullivan,et al.  Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis , 2011, Arthritis research & therapy.

[56]  R. Boellaard,et al.  18F-FDG PET as a Tool to Predict the Clinical Outcome of Infliximab Treatment of Rheumatoid Arthritis: An Explorative Study , 2011, The Journal of Nuclear Medicine.

[57]  P. Andersen,et al.  Polysynovitis after oligofructose overload in dairy cattle. , 2010, Journal of comparative pathology.

[58]  Xiao-Yu Song,et al.  Mechanical injury potentiates proteoglycan catabolism induced by interleukin-6 with soluble interleukin-6 receptor and tumor necrosis factor alpha in immature bovine and adult human articular cartilage. , 2009, Arthritis and rheumatism.

[59]  C. Ohlsson,et al.  Dichloroacetate alleviates development of collagen II-induced arthritis in female DBA/1 mice , 2009, Arthritis research & therapy.

[60]  K. Ohtomo,et al.  Inflammatory Cytokines and Hypoxia Contribute to 18F-FDG Uptake by Cells Involved in Pannus Formation in Rheumatoid Arthritis , 2009, Journal of Nuclear Medicine.

[61]  A. L. Stevens,et al.  A sodium dodecyl sulfate-polyacrylamide gel electrophoresis-liquid chromatography tandem mass spectrometry analysis of bovine cartilage tissue response to mechanical compression injury and the inflammatory cytokines tumor necrosis factor alpha and interleukin-1beta. , 2008, Arthritis and rheumatism.

[62]  W. Fulkerson,et al.  Clinical acidosis in a Gippsland dairy herd. , 2005, Australian veterinary journal.

[63]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[64]  D. Pressey.  Friend or FoE? , 1983, Nature.

[65]  P. Liberg,et al.  Blood Serum and Synovial Fluid in Bovine Laminitis and Arthritis, with Particular Reference to the Protein Composition , 1980, Acta Veterinaria Scandinavica.