A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors
暂无分享,去创建一个
Paul A Clemons | Andrea Califano | Mariano J. Alvarez | Daniel Kaemmerer | Shereen Ezzat | Ülo Langel | Arul M Chinnaiyan | Kay Washington | Lisa Bodei | Bertram Wiedenmann | Stuart Schreiber | Charles Karan | Mariano J Alvarez | Mark Kidd | Irvin Modlin | Andrea Frilling | Adina Grunn | Diane Reidy-Lagunes | Beatrice S Knudsen | Andrew L Kung | Roberto Bergamaschi | P. Clemons | A. Chinnaiyan | S. Schreiber | D. Metz | H. Kim | K. Washington | Laura H. Tang | A. Califano | A. Grunn | A. Rustgi | A. Sepulveda | S. Ezzat | M. Alvarez | R. Bergamaschi | I. Modlin | V. Livolsi | G. Rieckhof | A. Kung | B. Wiedenmann | S. Serra | Kyoung-Mee Kim | B. Knudsen | Xiaopu Yuan | Afshin Ghavami | Jeeyun Lee | L. Kunju | Ü. Langel | D. Jaeger | P. Subramaniam | Ronald B. Realubit | Charles Karan | M. Kim | H. Remotti | M. Kidd | J. Milsom | Jakob Regberg | C. Shi | F. D. Dela Cruz | Daniel Diolaiti | R. Roses | L. Bodei | Chanjuan Shi | Jeeyun Lee | Mahalaxmi Aburi | E. Komissarova | Elizabeth Hagan | D. Dhall | Douglas A. Fraker | D. Kaemmerer | Zhong Li | Hai Li | R. Pfragner | Allison R. Rainey | M. Barberis | Tony Detre | A. Frilling | M. Hommann | E. Leahy | Y. Park | D. Reidy-Lagunes | Massimo Barberis | Helen Remotti | David C Metz | Dirk Jaeger | Robert Roses | Laura H Tang | Deepti Dhall | Xiaopu Yuan | Jeffrey W Milsom | Lakshmi P Kunju | Hai Li | Mahalaxmi Aburi | Daniel Diolaiti | Antonia R Sepulveda | Elena V Komissarova | Afshin Ghavami | Filemon S Dela Cruz | Roswitha Pfragner | Gabrielle Rieckhof | Stefano Serra | Prem S Subramaniam | Elizabeth A Hagan | Douglas A Fraker | Kyoung M Kim | Hee C Kim | Zhong Li | Virginia LiVolsi | Allison R Rainey | Ronald B Realubit | Jakob Regberg | Anil Rustgi | Tony Detre | Merten Hommann | Michelle K Kim | Emer Leahy | Young S Park | Elizabeth A. Hagan | D. Fraker | D. Reidy‐Lagunes
[1] R. Young,et al. Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma. , 2018, Cancer discovery.
[2] Mariano J. Alvarez,et al. An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis. , 2017, Cell reports.
[3] Mariano J. Alvarez,et al. The recurrent architecture of tumour initiation, progression and drug sensitivity , 2016, Nature Reviews Cancer.
[4] I. Tannock,et al. Limits to Personalized Cancer Medicine. , 2016, The New England journal of medicine.
[5] S. Severi,et al. A Delphic consensus assessment: imaging and biomarkers in gastroenteropancreatic neuroendocrine tumor disease management , 2016, Endocrine connections.
[6] P. Engstrom,et al. Molecular profiling of neuroendocrine malignancies to identify prognostic and therapeutic markers: a Fox Chase Cancer Center Pilot Study , 2016, British Journal of Cancer.
[7] Mariano J. Alvarez,et al. Network-based inference of protein activity helps functionalize the genetic landscape of cancer , 2016, Nature Genetics.
[8] Andrea Califano,et al. Elucidation and Pharmacological Targeting of Novel Molecular Drivers of Follicular Lymphoma Progression. , 2016, Cancer research.
[9] Andrea Califano,et al. Predicting Drug Response in Human Prostate Cancer from Preclinical Analysis of In Vivo Mouse Models. , 2015, Cell reports.
[10] A. Califano,et al. Inhibition of the autocrine IL-6-JAK2-STAT3-calprotectin axis as targeted therapy for HR-/HER2+ breast cancers. , 2015, Genes & development.
[11] S. Hensley,et al. Identification of Hemagglutinin Residues Responsible for H3N2 Antigenic Drift during the 2014-2015 Influenza Season. , 2015, Cell reports.
[12] S. Friend,et al. Impact of centralization on aCGH-based genomic profiles for precision medicine in oncology. , 2015, Annals of oncology : official journal of the European Society for Medical Oncology.
[13] Matthew E. Ritchie,et al. limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.
[14] W. Hahn,et al. Prospective enterprise-level molecular genotyping of a cohort of cancer patients. , 2014, The Journal of molecular diagnostics : JMD.
[15] Samantha A. Morris,et al. CellNet: Network Biology Applied to Stem Cell Engineering , 2014, Cell.
[16] Mariano J. Alvarez,et al. Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy. , 2014, Cancer cell.
[17] Andrea Califano,et al. Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. , 2013, Cancer cell.
[18] Trevor J Pugh,et al. Somatic mutation of CDKN1B in small intestine neuroendocrine tumors , 2013, Nature Genetics.
[19] Joshua C. Gilbert,et al. An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules , 2013, Cell.
[20] Michael B Atkins,et al. Which drug, and when, for patients with BRAF-mutant melanoma? , 2013, The Lancet. Oncology.
[21] R. Salazar,et al. Gastroenteropancreatic neuroendocrine tumors: diagnosis and treatment , 2013, Annals of gastroenterology.
[22] Adam A. Margolin,et al. The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity , 2012, Nature.
[23] J. Rosai. The origin of neuroendocrine tumors and the neural crest saga , 2011, Modern Pathology.
[24] Michael A. Choti,et al. DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors , 2011, Science.
[25] C. I. Smith,et al. PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation , 2011, Nucleic acids research.
[26] Benito Munoz,et al. Towards patient-based cancer therapeutics , 2010, Nature Biotechnology.
[27] Mariano J. Alvarez,et al. A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers , 2010, Molecular systems biology.
[28] Wei Keat Lim,et al. The transcriptional network for mesenchymal transformation of brain tumors , 2009, Nature.
[29] Andrea Califano,et al. Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells. , 2008, Blood.
[30] B. A. Hocevar,et al. Progression and treatment of HER2-positive breast cancer , 2010, Cancer Chemotherapy and Pharmacology.
[31] R. Dalla‐Favera,et al. Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma , 2009, Nature.
[32] E. Ingolič,et al. Establishment and characterization of three novel cell lines - P-STS, L-STS, H-STS - derived from a human metastatic midgut carcinoid. , 2009, Anticancer research.
[33] Ji Luo,et al. Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction , 2009, Cell.
[34] Cole Trapnell,et al. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.
[35] H. Nagawa,et al. Prognosis and risk factors of metastasis in colorectal carcinoids: results of a nationwide registry over 15 years , 2007, Gut.
[36] J. Collins,et al. Large-Scale Mapping and Validation of Escherichia coli Transcriptional Regulation from a Compendium of Expression Profiles , 2007, PLoS biology.
[37] Chris Wiggins,et al. ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context , 2004, BMC Bioinformatics.
[38] B. Eriksson,et al. Endocrine tumours of the pancreas. , 2005, Best practice & research. Clinical gastroenterology.
[39] Adam A. Margolin,et al. Reverse engineering of regulatory networks in human B cells , 2005, Nature Genetics.
[40] Jean YH Yang,et al. Bioconductor: open software development for computational biology and bioinformatics , 2004, Genome Biology.
[41] I. Weinstein. Addiction to Oncogenes--the Achilles Heal of Cancer , 2002, Science.
[42] M. Ashburner,et al. Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.
[43] E. Ingolič,et al. Establishment of a continuous cell line from a human carcinoid of the small intestine (KRJ-I). , 1996, International journal of oncology.