Charles F. Kettring prize. Fundamental studies with cisplatin

[1]  F. M. Sinex,et al.  Specific binding of antitumour drug cis-Pt(NH3)2Cl2 to DNA rich in guanine and cytosine , 1974, Nature.

[2]  T. Theophanides,et al.  DNA-platinum interactions. Characterization of solid DNAK2[PtCl4 complexes , 1976 .

[3]  S. Rešlová,et al.  The induction of lysogenic strains of Escherichia coli by cis-dichloro-diammineplatinum (II). , 1971, Chemico-biological interactions.

[4]  J. Trosko,et al.  Platinum Compounds: a New Class of Potent Antitumour Agents , 1969, Nature.

[5]  D. Martin,et al.  Trans-dichlorodiammineplatinum(II). Acid hydrolysis and the isotopic exchange of the chloride ligands , 1961 .

[6]  J. De,et al.  Continuous intravenous bleomycin (NSC-125066) therapy with vinblastine (NSC-49842) in stage III testicular neoplasia. , 1975 .

[7]  B. Ames,et al.  Mutagenicity of cancer chemotherapeutic agents in the Salmonella/microsome test. , 1977, Cancer research.

[8]  L. M. Atkins,et al.  Potentiating action of 5-fluorouracil when used in combination with platinium compounds and cyclophosphamide in treatment of advanced L1210 leukemia. , 1978, Bioinorganic Chemistry.

[9]  J. Burchenal,et al.  Studies of cross-resistance, synergistic combinations and blocking of activity of platinum derivatives , 1978 .

[10]  P. Horacek,et al.  Interaction of cis-dichlorodiammineplatinum (II) with DNA. , 1971, Biochimica et biophysica acta.

[11]  B. Carr,et al.  cis-Platinum (II) Diamminedichloride , 1974 .

[12]  L. M. Atkins,et al.  Chemotherapy of advanced L1210 leukemia with platinum compounds in combination with other antitumor agents. , 1977, Cancer treatment reports.

[13]  C. Paoletti,et al.  Relative efficiencies of a series of square-planar plantinum(II) compounds on Salmonella mutagenesis. , 1977, Mutation research.

[14]  P. Kleihues,et al.  Chemical carcinogenesis in the nervous system. , 1976, International review of experimental pathology.

[15]  S. Lippard,et al.  Binding of platinum and palladium metallointercalation reagents and antitumor drugs to closed and open DNAs. , 1976, Biochemistry.

[16]  L. M. Atkins,et al.  Binding of an antitumor platinum compound to cells as influenced by physical factors and pharmacologically active agents. , 1973, Cancer research.

[17]  BARNETT ROSENBERG,et al.  Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode , 1965, Nature.

[18]  J. Burchenal,et al.  Lack of cross-resistance between certain platinum coordination compounds in mouse leukemia. , 1977, Cancer research.

[19]  J. Ward,et al.  Prevention of renal failure in rats receiving cis-diamminedichloroplatinum(II) by administration of furosemide. , 1977, Cancer research.

[20]  D. Goodgame,et al.  Possible mode of action of anti-tumour platinum drugs: X-ray evidence for cis binding by platinum of two inosine 5′-monophosphate molecules via the N(7) positions , 1975 .

[21]  G. Goldenberg,et al.  Evidence for a transport carrier of nitrogen mustard in nitrogen mustard-sensitive and -resistant L5178Y lymphoblasts. , 1970, Cancer research.

[22]  B. Rosenberg,et al.  Actions of cis-diamminedichloroplatinum on cell surface nucleic acids in cancer cells as determined by cell electrophoresis techniques. , 1982, Cancer research.

[23]  R. Wagner,et al.  Cell-surface-associated nucleic acid in tumorigenic cells made visible with platinum-pyrimidine complexes by electron microscopy. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[24]  J. Venditti,et al.  The enhanced therapeutic effect of cis-platinum (II) diamminodichloride against L1210 leukemia when combined with cyclophosphamide or 1,2-bis(3,5-dioxopiperazine-1-yl)propane or several other antitumor agents. , 1973, Chemotherapy.

[25]  J. Miller,et al.  Carcinogenicity of antitumor cis-platinum(II) coordination complexes in the mouse and rat. , 1979, Cancer research.

[26]  H. C. Harder,et al.  Inhibitory effects of anti‐tumor platinum compounds on DNA, RNA and protein syntheses in mammalian cells in vitro , 1970, International journal of cancer.

[27]  T. F. Patton,et al.  Pharmacokinetics of non-protein-bound platinum species following administration of cis-dichlorodiammineplatinum(II). , 1979, Cancer treatment reports.

[28]  K. Kohn,et al.  Mechanism of action of cis-dichlorodiammineplatinum(II). , 1979, Cancer treatment reports.

[29]  R. Brubaker,et al.  Mutagenic properties of cis-plantinum(II)diammino-dichloride in Escherichia coli. , 1975, Mutation research.

[30]  Hugh S. Thompson,et al.  Cis-Dichlorodiammineplatinum [II]: Inhibition of Nucleic Acid Synthesis in Lymphocytes Stimulated with Phytohemagglutinin 1 , 1971, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[31]  S. Mansy,et al.  Binding of cis- and trans-dichlorodiammineplatinum(II) to nucleosides. I. Location of the binding sites. , 1973, Journal of the American Chemical Society.

[32]  R. P. Spencer,et al.  Synthesis and distribution of a radiolabeled antitumor agent: cis-diamminedichloroplatinum. II. , 1972, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[33]  D. M. Watkins,et al.  Anti-tumour platinum complexes : relationships between chemical properties and activity , 1978 .

[34]  A J Thomson,et al.  The inhibition of growth or cell division in Escherichia coli by different ionic species of platinum(IV) complexes. , 1967, The Journal of biological chemistry.

[35]  H. Wallace,et al.  Phase I Evaluation of cis-Platinum (II) Diamminedichloride (PDD) and a Combination of PDD Plus Adriamycin , 1974 .

[36]  R. Davis,et al.  cis-Dichlorodiammineplatinum(II) (NSC-119 875): preclinical toxicologic evaluation of intravenous injection in dogs, monkeys and mice. , 1973, Toxicology and applied pharmacology.

[37]  L. Einhorn,et al.  Cis-diamminedichloroplatinum, vinblastine, and bleomycin combination chemotherapy in disseminated testicular cancer. , 1977, Annals of internal medicine.

[38]  J. Jordanov,et al.  Interaction of cis-diaminotolueneplatinum(II) with nucleosides: evidence for guanosine O(6).N(7) chelation by platinum , 1976 .

[39]  J. Drobník,et al.  The effect of cis-platinum (II) diamminodichloride on bone marrow. , 1972, Cancer research.

[40]  D. J. Beck,et al.  Mutagenicity of platinum coordination complexes in Salmonella typhimurium. , 1980, Mutation research.

[41]  J. Drobník,et al.  Effect of cis-dichlorodiamine platinum (II) on the post-irradiation lethality in mice after irradiation with X-rays. , 1971, Strahlentherapie.

[42]  C. Monti-Bragadin,et al.  Mutagenic activity of platinum and ruthenium complexes. , 1975, Chemico-biological interactions.

[43]  M. Pera,et al.  Effects of mannitol or furosemide diuresis on the nephrotoxicity and physiological disposition of cis-dichlorodiammineplatinum-(II) in rats. , 1979, Cancer research.

[44]  A. Thomson,et al.  The mechanism of action of antitumor platinum compounds. , 1979, Progress in nucleic acid research and molecular biology.

[45]  G. Gale,et al.  Cis-dichlorodiammineplatinum (II). Persistent and selective inhibition of deoxyribonucleic acid synthesis in vivo. , 1970, Biochemical pharmacology.

[46]  R. G. Fischer,et al.  "Platinum-pyrimidine blues" and related complexes: a new class of potent antitumor agents. , 1975, Cancer chemotherapy reports.

[47]  T. A. Connors,et al.  New platinum complexes with anti-tumour activity. , 1972, Chemico-biological interactions.

[48]  A. Guarino,et al.  Disposition and distribution of platinum following parenteral administration of cis-dichlorodiammineplatinum(II) to animals. , 1979, Cancer treatment reports.

[49]  J. Roberts,et al.  Cross-linking of Complementary Strands of DNA in Mammalian Cells by Antitumour Platinum Compounds , 1972, Nature.

[50]  W. Wolf.  Synthesis and distribution of ^ Pt cis-dichlorodiammineplatinum (II) , 1976 .

[51]  M. F. Ethier,et al.  Ototoxicity of cis-dichlorodiammine platinum (II) in the guinea pig. , 1975, Toxicology and applied pharmacology.

[52]  J. Russell,et al.  Leukemia in AKR mice: a defined suppressor cell population expressing membrane-associated DNA. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[53]  Kociba Rj,et al.  Acute toxicologic and pathologic effects of cis-diamminedichloroplatinum (NSC-119875) in the male rat. , 1971 .

[54]  D. Scudiero,et al.  Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains , 1980, Nature.

[55]  R. Golbey,et al.  High dose Cis‐platinum diammine dichloride. Amelioration of renal toxicity by mannitol diuresis , 1977, Cancer.

[56]  H. Bruckner,et al.  Chemotherapy of gynecological tumors with platinum II , 1977 .

[57]  L. M. Atkins,et al.  Synergistic action of high‐dose hydroxyurea when used with cyglophosphamide and certain new organoplatinum complexes in treatment of advanced L1210 leukemia , 1978, Cancer.

[58]  M. Wolpert-DeFilippes.  Antitumor activity of cis-dichlorodiammineplatinum(II). , 1979, Cancer treatment reports.