A review of the application of mesenchymal stem cells in the field of hematopoietic stem cell transplantation

[1]  O. Ringdén,et al.  Mesenchymal stromal cells as treatment for acute respiratory distress syndrome. Case Reports following hematopoietic cell transplantation and a review , 2022, Frontiers in Immunology.

[2]  J. Pérez-Simón,et al.  Mesenchymal Stromal Cells for Treating Steroid-Resistant Acute and Chronic Graft Versus Host Disease: A Multicenter Compassionate Use Experience , 2022, Stem cells translational medicine.

[3]  Shunqing Wang,et al.  Mesenchymal stromal cells plus basiliximab, calcineurin inhibitor as treatment of steroid-resistant acute graft-versus-host disease: a multicenter, randomized, phase 3, open-label trial , 2022, Journal of Hematology & Oncology.

[4]  Hong Wang,et al.  Allogeneic Stem Cell Transplantation Combined With Transfusion of Mesenchymal Stem Cells in Primary Myelofibrosis: A Multicenter Retrospective Study , 2022, Frontiers in Oncology.

[5]  E. Ovalı,et al.  Co‐transplantation of mesenchymal stromal cell and haploidentical hematopoietic stem cell with TCR αβ depletion in children with primary immunodeficiency syndromes , 2021, Pediatric transplantation.

[6]  K. Shah,et al.  Mesenchymal Stem Cell Immunomodulation: Mechanisms and Therapeutic Potential. , 2020, Trends in pharmacological sciences.

[7]  Liyan Guo,et al.  Extracellular vesicles derived from mesenchymal stem cells prevent skin fibrosis in the cGVHD mouse model by suppressing the activation of macrophages and B cells immune response. , 2020, International immunopharmacology.

[8]  E. Shpall,et al.  A Phase 3 randomized study of Remestemcel-L versus placebo added to second line therapy in patients with steroid refractory acute graft versus host disease. , 2020, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[9]  Xiang Ren,et al.  Multifaceted characterization of the signatures and efficacy of mesenchymal stem/stromal cells in acquired aplastic anemia , 2020, Stem Cell Research & Therapy.

[10]  C. Govind,et al.  Mesenchymal stem cells: Cell therapy and regeneration potential , 2019, Journal of tissue engineering and regenerative medicine.

[11]  A. Bacigalupo,et al.  Haploidentical donor transplants for severe aplastic anemia. , 2019, Seminars in hematology.

[12]  F. Baron,et al.  Comparison of Mesenchymal Stromal Cells From Different Origins for the Treatment of Graft-vs.-Host-Disease in a Humanized Mouse Model , 2019, Front. Immunol..

[13]  F. Wang,et al.  Exosomal sphingosine 1‐phosphate secreted by mesenchymal stem cells regulated Treg/Th17 balance in aplastic anemia , 2019, IUBMB life.

[14]  Xialin Liu,et al.  A potent immunomodulatory role of exosomes derived from mesenchymal stromal cells in preventing cGVHD , 2018, Journal of Hematology & Oncology.

[15]  He Huang,et al.  The consensus on the monitoring, treatment, and prevention of leukemia relapse after allogeneic hematopoietic stem cell transplantation in China. , 2018, Cancer letters.

[16]  X. Luan,et al.  Human placenta-derived mesenchymal stem cells ameliorate GVHD by modulating Th17/Tr1 balance via expression of PD-L2. , 2018, Life sciences.

[17]  Wu-chun Feng,et al.  Donor-derived marrow mesenchymal stromal cell co-transplantation following a haploidentical hematopoietic stem cell transplantation trail to treat severe aplastic anemia in children , 2018, Annals of Hematology.

[18]  Xiaojian Wu,et al.  Bone marrow-derived CXCR4-overexpressing MSCs display increased homing to intestine and ameliorate colitis-associated tumorigenesis in mice , 2018, Gastroenterology report.

[19]  M. Remberger,et al.  Placenta‐Derived Decidua Stromal Cells for Treatment of Severe Acute Graft‐Versus‐Host Disease , 2018, Stem cells translational medicine.

[20]  A. Spittler,et al.  Isolation, cultivation, and characterization of human mesenchymal stem cells , 2018, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[21]  N. Arsenijević,et al.  Mesenchymal stem cell‐derived factors: Immuno‐modulatory effects and therapeutic potential , 2017, BioFactors.

[22]  C. Min,et al.  Mesenchymal Stem Cells (MSCs) Attenuate Cutaneous Sclerodermatous Graft-Versus-Host Disease (Scl-GVHD) through Inhibition of Immune Cell Infiltration in a Mouse Model. , 2017, The Journal of investigative dermatology.

[23]  C. Solano,et al.  Adipose tissue-derived mesenchymal stromal cells as part of therapy for chronic graft-versus-host disease: A phase I/II study. , 2017, Cytotherapy.

[24]  Y. Pei,et al.  Improved outcome of haploidentical transplantation in severe aplastic anemia using reduced-intensity fludarabine-based conditioning , 2017, Oncotarget.

[25]  M. Remberger,et al.  Safety and Side Effects of Using Placenta-Derived Decidual Stromal Cells for Graft-versus-Host Disease and Hemorrhagic Cystitis , 2017, Front. Immunol..

[26]  D. Covas,et al.  Mesenchymal stromal cell infusion to treat steroid-refractory acute GvHD III/IV after hematopoietic stem cell transplantation , 2017, Bone Marrow Transplantation.

[27]  J. Zugaza,et al.  Characteristics, applications and prospects of mesenchymal stem cells in cell therapy. , 2017 .

[28]  H. Xiao,et al.  Cotransplantation of bone marrow-derived mesenchymal stem cells in haploidentical hematopoietic stem cell transplantation in patients with severe aplastic anemia: an interim summary for a multicenter phase II trial results , 2017, Bone Marrow Transplantation.

[29]  GaoZhe,et al.  Extracellular Vesicles Released from Human Umbilical Cord-Derived Mesenchymal Stromal Cells Prevent Life-Threatening Acute Graft-Versus-Host Disease in a Mouse Model of Allogeneic Hematopoietic Stem Cell Transplantation. , 2016 .

[30]  C. Zhang,et al.  Phase II Multicenter, Randomized, Double-Blind Controlled Study of Efficacy and Safety of Umbilical Cord-Derived Mesenchymal Stromal Cells in the Prophylaxis of Chronic Graft-Versus-Host Disease After HLA-Haploidentical Stem-Cell Transplantation. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[31]  G. Lucchini,et al.  Mesenchymal stromal cells from pooled mononuclear cells of multiple bone marrow donors as rescue therapy in pediatric severe steroid-refractory graft-versus-host disease: a multicenter survey , 2016, Haematologica.

[32]  Giulio Cossu,et al.  No Identical “Mesenchymal Stem Cells” at Different Times and Sites: Human Committed Progenitors of Distinct Origin and Differentiation Potential Are Incorporated as Adventitial Cells in Microvessels , 2016, Stem cell reports.

[33]  B. Blanco,et al.  Immunomodulatory effects of bone marrow versus adipose tissue‐derived mesenchymal stromal cells on NK cells: implications in the transplantation setting , 2016, European journal of haematology.

[34]  E. Parovichnikova,et al.  Analysis of multipotent mesenchymal stromal cells used for acute graft‐versus‐host disease prophylaxis , 2016, European journal of haematology.

[35]  Ø. Bruserud,et al.  Co-transplantation of multipotent mesenchymal stromal cells in allogeneic hematopoietic stem cell transplantation: A systematic review and meta-analysis. , 2016, Cytotherapy.

[36]  K. Ozawa,et al.  Bone marrow-derived mesenchymal stem cells (JR-031) for steroid-refractory grade III or IV acute graft-versus-host disease: a phase II/III study , 2016, International Journal of Hematology.

[37]  G. Camussi,et al.  The secretome of mesenchymal stromal cells: Role of extracellular vesicles in immunomodulation. , 2015, Immunology letters.

[38]  Jia Wei,et al.  Efficacy of Mesenchymal Stem Cell Therapy for Steroid-Refractory Acute Graft-Versus-Host Disease following Allogeneic Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis , 2015, PloS one.

[39]  Baoan Chen,et al.  Umbilical cord blood transplantation supplemented with the infusion of mesenchymal stem cell for an adolescent patient with severe aplastic anemia: a case report and review of literature , 2015, Patient preference and adherence.

[40]  G Huls,et al.  Biomarker profiling of steroid-resistant acute GVHD in patients after infusion of mesenchymal stromal cells , 2015, Leukemia.

[41]  K. Zhao,et al.  Co-transplantation of Hematopoietic Stem Cells and Cxcr4 Gene-Transduced Mesenchymal Stem Cells Promotes Hematopoiesis , 2015, Cell Biochemistry and Biophysics.

[42]  H. Abele,et al.  Human Placenta-Derived CD146-Positive Mesenchymal Stromal Cells Display a Distinct Osteogenic Differentiation Potential. , 2015, Stem cells and development.

[43]  Shinn-Zong Lin,et al.  Human Umbilical Cord Mesenchymal Stem Cells: A New Era for Stem Cell Therapy , 2015, Cell transplantation.

[44]  E. Andreu,et al.  Sequential third-party mesenchymal stromal cell therapy for refractory acute graft-versus-host disease. , 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[45]  D. Martín-Pérez,et al.  The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function , 2014, eLife.

[46]  Depei Wu,et al.  Mesenchymal Stromal Cells as an Adjuvant Treatment for Severe Late-Onset Hemorrhagic Cystitis after Allogeneic Hematopoietic Stem Cell Transplantation , 2014, Acta Haematologica.

[47]  H. Li,et al.  Mesenchymal stromal cells infusions improve refractory chronic graft versus host disease through an increase of CD5+ regulatory B cells producing interleukin 10 , 2014, Leukemia.

[48]  M. Epple,et al.  MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease , 2014, Leukemia.

[49]  Chun-ji Gao,et al.  Reduced Intensity Conditioning, Combined Transplantation of Haploidentical Hematopoietic Stem Cells and Mesenchymal Stem Cells in Patients with Severe Aplastic Anemia , 2014, PloS one.

[50]  G. Lucchini,et al.  Treatment of graft versus host disease with mesenchymal stromal cells: a phase I study on 40 adult and pediatric patients. , 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[51]  Xiaodong Chen,et al.  Mesenchymal stem cells use IDO to regulate immunity in tumor microenvironment. , 2014, Cancer research.

[52]  J. Kurtzberg,et al.  Allogeneic human mesenchymal stem cell therapy (remestemcel-L, Prochymal) as a rescue agent for severe refractory acute graft-versus-host disease in pediatric patients. , 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[53]  L. Fouillard,et al.  Innovative cell therapy in the treatment of serious adverse events related to both chemo-radiotherapy protocol and acute myeloid leukemia syndrome: the infusion of mesenchymal stem cells post-treatment reduces hematopoietic toxicity and promotes hematopoietic reconstitution. , 2014, Current pharmaceutical biotechnology.

[54]  L. Marquez-Curtis,et al.  Enhancing the Migration Ability of Mesenchymal Stromal Cells by Targeting the SDF-1/CXCR4 Axis , 2013, BioMed research international.

[55]  F. Locatelli,et al.  Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid‐refractory, grade III–IV acute graft‐versus‐host disease , 2013, British journal of haematology.

[56]  Y. Chao,et al.  Human Application of Ex Vivo Expanded Umbilical Cord-Derived Mesenchymal Stem Cells: Enhance Hematopoiesis after Cord Blood Transplantation , 2013, Cell transplantation.

[57]  A. Nagler,et al.  Treatment of severe steroid resistant acute GVHD with mesenchymal stromal cells (MSC). , 2013, American journal of blood research.

[58]  R. Neumann,et al.  Lessons Learned about Human Stem Cell Responses to Ionizing Radiation Exposures: A Long Road Still Ahead of Us , 2013, International journal of molecular sciences.

[59]  K. Ozawa,et al.  Unrelated allogeneic bone marrow-derived mesenchymal stem cells for steroid-refractory acute graft-versus-host disease: a phase I/II study , 2013, International Journal of Hematology.

[60]  Zhong-chao Han,et al.  Cotransplantation of haploidentical hematopoietic and umbilical cord mesenchymal stem cells with a myeloablative regimen for refractory/relapsed hematologic malignancy , 2013, Annals of Hematology.

[61]  O. Ringdén,et al.  Decidual stromal cells promote regulatory T cells and suppress alloreactivity in a cell contact-dependent manner. , 2013, Stem cells and development.

[62]  C. Scheiermann,et al.  Mesenchymal stem cell: keystone of the hematopoietic stem cell niche and a stepping-stone for regenerative medicine. , 2013, Annual review of immunology.

[63]  J. Sheu,et al.  Cotransplantation of Umbilical Cord–Derived Mesenchymal Stem Cells Promote Hematopoietic Engraftment in Cord Blood Transplantation: A Pilot Study , 2013, Transplantation.

[64]  W. Xue,et al.  The Role of SDF-1-CXCR4/CXCR7 Axis in the Therapeutic Effects of Hypoxia-Preconditioned Mesenchymal Stem Cells for Renal Ischemia/Reperfusion Injury , 2012, PloS one.

[65]  R. Vishnubalaji,et al.  Comparative investigation of the differentiation capability of bone-marrow- and adipose-derived mesenchymal stem cells by qualitative and quantitative analysis , 2012, Cell and Tissue Research.

[66]  M. Horowitz,et al.  Risk factors for acute GVHD and survival after hematopoietic cell transplantation. , 2012, Blood.

[67]  Yu Wang,et al.  Coinfusion of mesenchymal stromal cells facilitates platelet recovery without increasing leukemia recurrence in haploidentical hematopoietic stem cell transplantation: a randomized, controlled clinical study. , 2011, Stem cells and development.

[68]  Yu-Hsiang Chang,et al.  Effective Treatment of Severe Steroid-Resistant Acute Graft-Versus-Host Disease With Umbilical Cord-Derived Mesenchymal Stem Cells , 2011, Transplantation.

[69]  A. Xiang,et al.  Mesenchymal stem cell as salvage treatment for refractory chronic GVHD , 2010, Bone Marrow Transplantation.

[70]  F. Baron,et al.  Cotransplantation of mesenchymal stem cells might prevent death from graft-versus-host disease (GVHD) without abrogating graft-versus-tumor effects after HLA-mismatched allogeneic transplantation following nonmyeloablative conditioning. , 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[71]  Ke Chen,et al.  Human umbilical cord mesenchymal stem cells hUC-MSCs exert immunosuppressive activities through a PGE2-dependent mechanism. , 2010, Clinical immunology.

[72]  R. Zhao,et al.  Efficacy of bone marrow-derived mesenchymal stem cells in the treatment of sclerodermatous chronic graft-versus-host disease: clinical report. , 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[73]  Q. Han,et al.  Mesenchymal stem cells for the treatment of refractory pure red cell aplasia after major ABO-incompatible hematopoietic stem cell transplantation , 2009, Annals of Hematology.

[74]  S. Goldenberg,et al.  Dissimilar Differentiation of Mesenchymal Stem Cells from Bone Marrow, Umbilical Cord Blood, and Adipose Tissue , 2008, Experimental biology and medicine.

[75]  G. Dini,et al.  Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study , 2008, The Lancet.

[76]  R. Zhao,et al.  Favorable response to human adipose tissue-derived mesenchymal stem cells in steroid-refractory acute graft-versus-host disease. , 2007, Transplantation proceedings.

[77]  R. Zhao,et al.  Human adipose tissue‐derived mesenchymal stromal cells as salvage therapy for treatment of severe refractory acute graft‐vs.‐host disease in two children , 2007, Pediatric transplantation.

[78]  L. Henningsohn,et al.  Tissue repair using allogeneic mesenchymal stem cells for hemorrhagic cystitis, pneumomediastinum and perforated colon , 2007, Leukemia.

[79]  Franco Locatelli,et al.  Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation. , 2007, Blood.

[80]  M. Yen,et al.  Placenta‐Derived Multipotent Cells Exhibit Immunosuppressive Properties That Are Enhanced in the Presence of Interferon‐γ , 2006, Stem cells.

[81]  R. Yañez,et al.  Adipose Tissue‐Derived Mesenchymal Stem Cells Have In Vivo Immunosuppressive Properties Applicable for the Control of the Graft‐Versus‐Host Disease , 2006, Stem cells.

[82]  Hermann Eichler,et al.  Comparative Analysis of Mesenchymal Stem Cells from Bone Marrow, Umbilical Cord Blood, or Adipose Tissue , 2006, Stem cells.

[83]  Moustapha Hassan,et al.  Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells , 2004, The Lancet.

[84]  C. Baird.  The pilot study. , 2000, Orthopedic nursing.

[85]  S. Zheng,et al.  Erratum: Human gingiva tissue-derived MSC ameliorates immune-mediated bone marrow failure of aplastic anemia via suppression of Th1 and Th17 cells and enhancement of CD4+Foxp3+ regulatory T cells differentiation. , 2020, American journal of translational research.

[86]  S. Zheng,et al.  Human gingiva tissue-derived MSC ameliorates immune-mediated bone marrow failure of aplastic anemia via suppression of Th1 and Th17 cells and enhancement of CD4+Foxp3+ regulatory T cells differentiation. , 2019, American journal of translational research.

[87]  M. Murad,et al.  Survival after mesenchymal stromal cell therapy in steroid-refractory acute graft-versus-host disease: systematic review and meta-analysis. , 2016, The Lancet. Haematology.

[88]  Xiuli Wu,et al.  Immunomodulation effects of mesenchymal stromal cells on acute graft-versus-host disease after hematopoietic stem cell transplantation. , 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[89]  Y. Li,et al.  The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study , 2008, Leukemia.

[90]  Qin-jun Zhao,et al.  Isolation and characterization of human umbilical cord mesenchymal stem cells with hematopoiesis-supportive function and other potentials. , 2006, Haematologica.

[91]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..