meta-DENSE complex acquisition for reduced intravoxel dephasing.

Displacement encoding with stimulated echoes (DENSE) with a meta-DENSE readout and RF phase cycling to suppress the STEAM anti-echo is described for reducing intravoxel dephasing signal loss. This RF phase cycling scheme, when combined with existing meta-DENSE suppression of the T1 recovering signal, yields higher quality DENSE myocardial strain maps. Phantom and human images are provided to demonstrate the technique, which is capable of acquiring phase contrast displacement encoded images at low encoding gradient strengths providing better spatial resolution and less signal loss due to intravoxel dephasing than prior methods.

[1]  Christopher M Kramer,et al.  Myocardial tissue tracking with two-dimensional cine displacement-encoded MR imaging: development and initial evaluation. , 2004, Radiology.

[2]  Gil Navon,et al.  AIR-SPAMM: alternative inversion recovery spatial modulation of magnetization for myocardial tagging. , 2004, Journal of magnetic resonance.

[3]  H. Wen,et al.  DENSE: displacement encoding with stimulated echoes in cardiac functional MRI. , 1999, Journal of magnetic resonance.

[4]  H. Wen,et al.  Mixed echo train acquisition displacement encoding with stimulated echoes: An optimized DENSE method for in vivo functional imaging of the human heart , 2001, Magnetic resonance in medicine.

[5]  H. Wen,et al.  High-resolution strain analysis of the human heart with fast-DENSE. , 1999, Journal of magnetic resonance.

[6]  J. Frahm,et al.  High‐speed STEAM MRI of the human heart , 1991, Magnetic resonance in medicine.

[7]  I. Smith,et al.  Stimulated anti-echo selection in spatially localized NMR spectroscopy. , 1999, Journal of magnetic resonance.

[8]  J. Frahm,et al.  Localized proton NMR spectroscopy of brain tumors using short-echo time STEAM sequences. , 1991, Journal of computer assisted tomography.

[9]  R M Weisskoff,et al.  MRI signal void due to in‐plane motion is all‐or‐none , 1994, Magnetic resonance in medicine.

[10]  Peter Boesiger,et al.  Myocardial tagging with 3D‐CSPAMM , 2002, Journal of magnetic resonance imaging : JMRI.

[11]  S. Maier,et al.  Improved myocardial tagging contrast , 1993, Magnetic resonance in medicine.