Adverse event management of mTOR inhibitors during treatment of hormone receptor-positive advanced breast cancer: considerations for oncologists.
暂无分享,去创建一个
[1] M. Piccart,et al. Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis , 2013, Advances in Therapy.
[2] S. Sonis,et al. Oral ulcers in patients with advanced breast cancer receiving everolimus: a case series report on clinical presentation and management. , 2013, Oral surgery, oral medicine, oral pathology and oral radiology.
[3] R. Chlebowski. Changing concepts of hormone receptor-positive advanced breast cancer therapy. , 2013, Clinical breast cancer.
[4] G. Hortobagyi,et al. Clinical management and resolution of stomatitis in BOLERO-2. , 2013 .
[5] G. Hortobagyi,et al. Incidence, management, and resolution of noninfectious pneumonitis in BOLERO-2. , 2013 .
[6] P. Neven,et al. Health‐related quality of life of patients with advanced breast cancer treated with everolimus plus exemestane versus placebo plus exemestane in the phase 3, randomized, controlled, BOLERO‐2 trial , 2013, Cancer.
[7] David Chen,et al. Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial , 2013, The Lancet.
[8] E. Thiele,et al. Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial , 2013, The Lancet.
[9] R. Motzer,et al. Clinical and histopathologic characteristics of rash in cancer patients treated with mammalian target of rapamycin inhibitors , 2012, Cancer.
[10] J. Dancey,et al. Management of metabolic effects associated with anticancer agents targeting the PI3K-Akt-mTOR pathway. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[11] B. Kasiske,et al. A Prospective, Multinational Pharmacoepidemiological Study of Clinical Conversion to Sirolimus Immunosuppression after Renal Transplantation , 2012, Journal of transplantation.
[12] I. Ray-Coquard,et al. Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: a GINECO study. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[13] M. Davila,et al. Reactivation of hepatitis B virus and hepatitis C virus in patients with cancer , 2012, Nature Reviews Clinical Oncology.
[14] M. Piccart,et al. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. , 2012, The New England journal of medicine.
[15] J. Machiels,et al. An international expanded-access programme of everolimus: addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy. , 2012, European journal of cancer.
[16] A. Larionov,et al. Edinburgh Research Explorer Understanding the mechanisms of aromatase inhibitor resistance , 2022 .
[17] V. Basevi,et al. Standards of Medical Care in Diabetes—2012 , 2011, Diabetes Care.
[18] Jeffrey W. Clark,et al. Phase 1/2 study of everolimus in advanced hepatocellular carcinoma , 2011, Cancer.
[19] A. Paci,et al. Natural history, management and pharmacokinetics of everolimus-induced-oral ulcers: insights into compliance issues. , 2011, European journal of cancer.
[20] G. Demetri,et al. Clinical presentation and management of mTOR inhibitor-associated stomatitis. , 2011, Oral oncology.
[21] N. Treister,et al. Managing stomatitis in patients treated with Mammalian target of rapamycin inhibitors. , 2011, Clinical journal of oncology nursing.
[22] S. Fox,et al. “Overcoming breast cancer drug resistance with mTOR inhibitors”. Could it be a myth or a real possibility in the short-term future? , 2011, Breast Cancer Research and Treatment.
[23] M. Taskinen,et al. ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). , 2011, Atherosclerosis.
[24] C. Porta,et al. Management of adverse events associated with the use of everolimus in patients with advanced renal cell carcinoma. , 2011, European journal of cancer.
[25] A. Brenner,et al. Common toxicities of mammalian target of rapamycin inhibitors , 2011, Targeted Oncology.
[26] E. D. de Vries,et al. Everolimus for advanced pancreatic neuroendocrine tumors. , 2011, The New England journal of medicine.
[27] Hyun-Ah Kim,et al. Phosphorylated S6K1 is a possible marker for endocrine therapy resistance in hormone receptor-positive breast cancer , 2011, Breast Cancer Research and Treatment.
[28] C. Mathers,et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 , 2010, International journal of cancer.
[29] Funda Meric-Bernstam,et al. Deciphering the role of PI3K/Akt/mTOR pathway in breast cancer biology and pathogenesis. , 2010, Clinical breast cancer.
[30] A. Ravaud,et al. Noninfectious pneumonitis after everolimus therapy for advanced renal cell carcinoma. , 2010, American journal of respiratory and critical care medicine.
[31] D. Rea,et al. Systematic review of aromatase inhibitors in the first-line treatment for hormone sensitive advanced or metastatic breast cancer , 2010, Breast Cancer Research and Treatment.
[32] L. Fallowfield,et al. Locally recurrent or metastatic breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. , 2010, Annals of oncology : official journal of the European Society for Medical Oncology.
[33] S. Johnston,et al. New Strategies in Estrogen Receptor–Positive Breast Cancer , 2010, Clinical Cancer Research.
[34] J. D. de Fijter,et al. mTOR inhibitor‐associated dermatologic and mucosal problems , 2010, Clinical transplantation.
[35] A. Kibel. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial , 2009 .
[36] L. Schwartz,et al. Characterization of Pneumonitis in Patients with Advanced Non-small Cell Lung Cancer Treated with Everolimus (RAD001) , 2009, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[37] G. Demetri,et al. Preliminary characterization of oral lesions associated with inhibitors of mammalian target of rapamycin in cancer patients , 2009, Cancer.
[38] Robert Dufour,et al. Canadian Cardiovascular Society / Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult – 2009 recommendations , 2009 .
[39] M. Ellis,et al. Activity of fulvestrant 500 mg versus anastrozole 1 mg as first-line treatment for advanced breast cancer: results from the FIRST study. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[40] Eric Sauerbrei,et al. Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[41] J. Pascual. The use of everolimus in renal-transplant patients , 2009, International journal of nephrology and renovascular disease.
[42] R. Greil,et al. Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[43] M. Pike,et al. American Journal of Epidemiology Original Contribution Breast Cancer Risk Factors Defined by Estrogen and Progesterone Receptor Status the Multiethnic Cohort Study , 2022 .
[44] Funda Meric-Bernstam,et al. Targeting the mTOR signaling network for cancer therapy. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[45] F. Giles,et al. The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents , 2009, Targeted Oncology.
[46] Yun Yen,et al. NCCN clinical practice guidelines in oncology: hepatobiliary cancers. , 2009, Journal of the National Comprehensive Cancer Network : JNCCN.
[47] B. Zinman,et al. Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy , 2009, Diabetes Care.
[48] Flora T. Musuamba,et al. Pharmacokinetics and dosage adjustment in patients with renal dysfunction , 2008, European Journal of Clinical Pharmacology.
[49] R. Motzer,et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial , 2008, The Lancet.
[50] A. Berkenblit,et al. Temsirolimus safety profile and management of toxic effects in patients with advanced renal cell carcinoma and poor prognostic features. , 2008, Annals of oncology : official journal of the European Society for Medical Oncology.
[51] S. Johnston,et al. Postmenopausal advanced breast cancer: options for therapy after tamoxifen and aromatase inhibitors. , 2006, Breast.
[52] Hanina Hibshoosh,et al. PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma. , 2005, Cancer research.
[53] Manuel Hidalgo,et al. Inhibition of mTOR Activity Restores Tamoxifen Response in Breast Cancer Cells with Aberrant Akt Activity , 2004, Clinical Cancer Research.
[54] Y. Samuels,et al. Oncogenic mutations of PIK3CA in human cancers. , 2004, Current topics in microbiology and immunology.
[55] Anthony Howell,et al. Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[56] M. Bjornsti,et al. The tor pathway: a target for cancer therapy , 2004, Nature Reviews Cancer.
[57] J. Mckenney,et al. National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) , 2002 .
[58] Nilanjan Chatterjee,et al. Estrogen Receptor Breast Cancer Phenotypes in the Surveillance, Epidemiology, and End Results Database , 2002, Breast Cancer Research and Treatment.
[59] O. Stål,et al. Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients , 2002, British Journal of Cancer.
[60] U. Christians,et al. Comparison of the in vitro metabolism of the macrolide immunosuppressants sirolimus and RAD. , 2001, Transplantation proceedings.
[61] J. Squifflet,et al. Sirolimus in association with mycophenolate mofetil induction for the prevention of acute graft rejection in renal allograft recipients. , 2000, Transplantation.