Total Synthesis of Amphidinolide E and Amphidinolide E Stereoisomers.

[1]  W. Roush,et al.  Synthesis of 2-epi-amphidinolide E: an unexpected and highly selective C(2)inversion during an esterification reaction. , 2007, Organic Letters.

[2]  A. Gradillas,et al.  Macrocyclization by ring-closing metathesis in the total synthesis of natural products: reaction conditions and limitations. , 2006, Angewandte Chemie.

[3]  A. Fürstner,et al.  Total synthesis of iejimalide B. , 2006, Angewandte Chemie.

[4]  A. Fürstner,et al.  Studies on iejimalide B: preparation of the seco acid and identification of the molecule's "Achilles heel". , 2006, Angewandte Chemie.

[5]  D. Curran,et al.  On the proof and disproof of natural product stereostructures: characterization and analysis of a twenty-eight member stereoisomer library of murisolins and their Mosher ester derivatives. , 2006, Journal of the American Chemical Society.

[6]  A. Fürstner,et al.  Total syntheses of amphidinolide X and Y. , 2006, Journal of the American Chemical Society.

[7]  Gang Zhao,et al.  Stereocontrolled and convergent total synthesis of amphidinolide T3. , 2006, The Journal of organic chemistry.

[8]  Arun K. Ghosh,et al.  Total synthesis and revision of C6 stereochemistry of (+)-amphidinolide W. , 2006, The Journal of organic chemistry.

[9]  B. Trost,et al.  Ru-catalyzed alkene-alkyne coupling. Total synthesis of amphidinolide P. , 2005, Journal of the American Chemical Society.

[10]  W. Roush,et al.  Synthesis of the A-B subunit of angelmicin B. , 2005, Organic letters.

[11]  J. A. Marshall,et al.  Synthesis of the C6-C21 segment of amphidinolide E. , 2005, Organic letters.

[12]  F. Sarabia,et al.  Total synthesis of Bengamide E and analogues by modification at C-2 and at terminal olefinic positions. , 2005, The Journal of organic chemistry.

[13]  W. Roush,et al.  Synthesis of (+)-bullatacin via the highly diastereoselective [3+2] annulation reaction of a racemic aldehyde and a nonracemic allylsilane. , 2005, Organic letters.

[14]  B. Trost,et al.  Total synthesis of (+)-amphidinolide A. Assembly of the fragments. , 2005, Journal of the American Chemical Society.

[15]  B. Trost,et al.  Total synthesis of (+)-amphidinolide A. Structure elucidation and completion of the synthesis. , 2005, Journal of the American Chemical Society.

[16]  W. Roush,et al.  [3 + 2]-annulation reactions of chiral allylsilanes and chiral aldehydes. studies on the synthesis of bis-tetrahydrofuran substructures of annonaceous acetogenins. , 2005, The Journal of organic chemistry.

[17]  K. Nicolaou,et al.  Metathesis reactions in total synthesis. , 2005, Angewandte Chemie.

[18]  W. Roush,et al.  Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. , 2005, Journal of the American Chemical Society.

[19]  T. Jamison,et al.  Synthesis of C13–C22 of amphidinolide T2 via nickel-catalyzed reductive coupling of an alkyne and a terminal epoxide , 2005 .

[20]  W. Roush,et al.  Efficient protiodesilylation of unactivated C(sp3)-SiMe2Ph bonds using tetrabutylammonium fluoride. , 2005, Organic letters.

[21]  G. C. Fu,et al.  Catalytic asymmetric synthesis of esters from ketenes. , 2005, Journal of the American Chemical Society.

[22]  T. Jamison,et al.  Total syntheses of amphidinolides T1 and T4 via catalytic, stereoselective, reductive macrocyclizations. , 2005, Journal of the American Chemical Society.

[23]  B. Trost,et al.  Dinuclear asymmetric Zn aldol additions: formal asymmetric synthesis of fostriecin. , 2005, Journal of the American Chemical Society.

[24]  A. Fürstner,et al.  Total synthesis of amphidinolide X. , 2004, Journal of the American Chemical Society.

[25]  V. Puranik,et al.  Towards the total synthesis of amphidinolide E: an enantioselective synthesis of C12-C29 fragment , 2004 .

[26]  B. Trost,et al.  Alkene-alkyne coupling as a linchpin: an efficient and convergent synthesis of amphidinolide P. , 2004, Journal of the American Chemical Society.

[27]  M. Crimmins,et al.  Enantioselective total synthesis of (+)-gigantecin: exploiting the asymmetric glycolate aldol reaction. , 2004, Journal of the American Chemical Society.

[28]  W. Roush,et al.  Synthesis of the C11-C29 fragment of amphidinolide F. , 2004, Organic letters.

[29]  W. Roush,et al.  Total synthesis of (-)-spinosyn A. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[30]  Y. Landais,et al.  Allylsilanes in Organic Synthesis − Recent Developments , 2004 .

[31]  H. Fuwa,et al.  Synthetic studies on antascomicin A: construction of the C18–C34 fragment , 2004 .

[32]  B. Trost,et al.  Structure elucidation of (+)-amphidinolide a by total synthesis and NMR chemical shift analysis. , 2004, Journal of the American Chemical Society.

[33]  Arun K. Ghosh,et al.  Total synthesis and structural revision of (+)-amphidinolide W. , 2004, Journal of the American Chemical Society.

[34]  M. Tsuda,et al.  Amphidinolides, bioactive macrolides from symbiotic marine dinoflagellates. , 2004, Natural product reports.

[35]  G. Evano,et al.  A convergent synthesis of the macrocyclic core of cytotrienins: application of RCM for macrocyclization. , 2004, Organic letters.

[36]  T. Jamison,et al.  Synthesis of amphidinolide T1 via catalytic, stereoselective macrocyclization. , 2004, Journal of the American Chemical Society.

[37]  P. Evans,et al.  Enantioselective total synthesis of the potent antitumor agent (-)-mucocin using a temporary silicon-tethered ring-closing metathesis cross-coupling reaction. , 2003, Journal of the American Chemical Society.

[38]  A. Fürstner,et al.  Total syntheses of amphidinolide T1, T3, T4, and T5. , 2003, Journal of the American Chemical Society.

[39]  K. Woerpel,et al.  [3 + 2] Annulation of allylic silanes in acyclic stereocontrol: total synthesis of (9S)-dihydroerythronolide A. , 2003, Journal of the American Chemical Society.

[40]  T. Scheper,et al.  The total synthesis of (-)-callystatin A. , 2003, Chemistry.

[41]  Arun K. Ghosh,et al.  Enantioselective total synthesis of (+)-amphidinolide t1. , 2003, Journal of the American Chemical Society.

[42]  M. Tsuda,et al.  Bioactive macrolides and polyketides from marine dinoflagellates , 2003 .

[43]  A. Fürstner,et al.  Total synthesis of amphidinolide T4. , 2002, Angewandte Chemie.

[44]  Yuichi Kobayashi,et al.  Formal total synthesis of fostriecin. , 2002, Organic letters.

[45]  B. Trost,et al.  An acid-catalyzed macrolactonization protocol. , 2002, Organic letters.

[46]  B. Trost,et al.  Ruthenium-catalyzed alkene-alkyne coupling: synthesis of the proposed structure of amphidinolide A. , 2002, Journal of the American Chemical Society.

[47]  K. Woerpel,et al.  Development of the [3 + 2] annulations of cyclohexenylsilanes and chlorosulfonyl isocyanate: application to the total synthesis of (+/-)-peduncularine. , 2002, Journal of the American Chemical Society.

[48]  K. Woerpel,et al.  Synthesis of (+/-)-5-epi-citreoviral and (+/-)-citreoviral and the kinetic resolution of an allylic silane by a [3 + 2] annulation. , 2002, Organic letters.

[49]  Joseph S. Ward,et al.  Total synthesis of proposed amphidinolide A via a highly selective ring-closing metathesis. , 2002, Organic letters.

[50]  T. Chou,et al.  Highly concise routes to epothilones: the total synthesis and evaluation of epothilone 490. , 2002, Journal of the American Chemical Society.

[51]  W. Roush,et al.  Diisopropyl tartrate modified (E)-crotylboronates: highly enantioselective propionate (E)-enolate equivalents , 2002 .

[52]  G. Pattenden,et al.  Total synthesis of the presumed amphidinolide A. , 2002, Angewandte Chemie.

[53]  T. Chakraborty,et al.  Chemistry of potent anti-cancer compounds, amphidinolides. , 2001, Current medicinal chemistry. Anti-cancer agents.

[54]  W. Roush,et al.  Studies on the synthesis of pectenotoxin II: synthesis of a C(11)-C(26) fragment precursor via [3 + 2]-annulation reactions of chiral allylsilanes. , 2001, Organic letters.

[55]  Z. Xia,et al.  Total synthesis of dendroamide A, a novel cyclic peptide that reverses multiple drug resistance. , 2001, The Journal of organic chemistry.

[56]  K. Woerpel,et al.  Stereoselective synthesis of substituted gamma-butyrolactones by the [3+2] annulation of allylic silanes with chlorosulfonyl isocyanate: enantioselective total synthesis of (+)-blastmycine. , 2001, Organic letters.

[57]  David R. Williams,et al.  Total synthesis of (+)-amphidinolide K. , 2001, Journal of the American Chemical Society.

[58]  A. Fürstner.  Olefin Metathesis and Beyond , 2000 .

[59]  A. Fürstner,et al.  Concise synthesis of (S,S)-(+)-dehydrohomoancepsenolide. , 2000, Organic letters.

[60]  David R. Williams,et al.  Total synthesis of (+)-amphidinolide P. [corrected]. , 2000, Organic letters.

[61]  A. Fürstner,et al.  Ring-Closing Alkyne Metathesis: Application to the Stereoselective Total Synthesis of Prostaglandin E2-1,15-Lactone , 2000 .

[62]  W. Roush,et al.  A Three-Component Coupling Strategy for Tetrahydrofuran Synthesis: Application of the Diisopropyl Tartrate Modified (E)-γ-(Dimethylphenylsilyl)allylboronate as an α,γ-Allyl Dianion Equivalent , 2000 .

[63]  E. Corey,et al.  Cuprous Chloride Accelerated Stille Reactions. A General and Effective Coupling System for Sterically Congested Substrates and for Enantioselective Synthesis , 1999 .

[64]  Y. Hamada,et al.  Mild and practical acylation of alcohols with esters or acetic anhydride under distannoxane catalysis , 1999 .

[65]  G. C. Fu,et al.  Enantioselective Addition of Alcohols to Ketenes Catalyzed by a Planar-Chiral Azaferrocene: Catalytic Asymmetric Synthesis of Arylpropionic Acids , 1999 .

[66]  Benjamin J. Swanson,et al.  Regio- and diastereoselective boron-mediated aldol reactions of chiral α,β,γ,δ-unsaturated N-acyloxazolidinones , 1998 .

[67]  David R. Williams,et al.  Total Synthesis of (+)-Amphidinolide J , 1998 .

[68]  A. Orita,et al.  Distannoxane-Catalyzed Highly Selective Acylation of Alcohols. , 1998, The Journal of organic chemistry.

[69]  W. A. Donaldson,et al.  Alkylation of tricarbonyl(diene)iron complexes: Model studies for the preparation of protomycinolide IV ☆ , 1997 .

[70]  K. Koyama,et al.  Studies on the Synthesis of Nargenicin A1: Highly Stereoselective Synthesis of the Complete Carbon Framework via the Transannular Diels−Alder Reaction of an 18-Membered Macrolide , 1996 .

[71]  C. Masse,et al.  Diastereoselective Reactions of Chiral Allyl and Allenyl Silanes with Activated C:X .pi.-Bonds , 1995 .

[72]  M. Tsuda,et al.  Absolute stereochemistry of amphidinolide E. , 1994, The Journal of organic chemistry.

[73]  E. Frérot,et al.  Coupling N-methylated amino acids using PyBroP and PyCloP halogenophosphonium salts : mechanism and fields of application , 1994 .

[74]  Y. Kita,et al.  A Novel Efficient Synthesis of 1-Ethoxyvinyl Esters and Their Use in Acylation of Amines and Alcohols: Synthesis of Water-Soluble Oxaunomycin Derivatives , 1994 .

[75]  G. E. Keck,et al.  An acylnitroso cycloaddition approach to the synthesis of highly oxygenated indolizidine alkaloids , 1993 .

[76]  J. Panek,et al.  A concise enantioselective synthesis of rans-olefin dipeptide isosteres , 1993 .

[77]  R. Riccio,et al.  Phosphated and sulphated marine polyhydroxylated steroids from the starfish Tremaster novaecaledoniae , 1993 .

[78]  M. Ishibashi,et al.  BIOACTIVE METABOLITES OF SYMBIOTIC MARINE MICROORGANISMS , 1993 .

[79]  J. Panek,et al.  Double stereodifferentiation in the Lewis acid promoted addition of chiral (E)-crotylsilanes with (S)-2-(benzyloxy)propanal. Effect of Lewis acid on reaction diastereoselection , 1993 .

[80]  K. Nakanishi,et al.  Determination of the absolute stereochemistry of nemadectins .alpha.2 and .alpha. , 1992 .

[81]  W. A. Donaldson,et al.  Diastereoselective alkylation of tricarbonyl(methyl 3,5-hexadienoate)iron , 1992 .

[82]  Michael G. Yang,et al.  Diastereoselective additions of chiral (E)-crotylsilanes to .alpha.-alkoxy and .beta.-alkoxy aldehydes. A one-step, silicon-directed tetrahydrofuran synthesis , 1991 .

[83]  H. Nozaki,et al.  Novel template effects of distannoxane catalysts in highly efficient transesterification and esterification , 1991 .

[84]  R. Riccio,et al.  Novel marine polyhydroxylated steroids from the starfish myxoderma platyacanthum , 1991 .

[85]  W. Roush,et al.  Acyclic diastereoselective synthesis using tartrate ester-modified crotylboronates. Double asymmetric reactions with .alpha.-methyl chiral aldehydes and synthesis of the C(19)-C(29) segment of rifamycin S , 1990 .

[86]  W. Roush,et al.  Asymmetric synthesis using tartrate ester modified allylboronates. 2. Single and double asymmetric reactions with alkoxy-substituted aldehydes , 1990 .

[87]  W. Roush,et al.  Asymmetric synthesis using tartrate ester modified allylboronates. 1. Factors influencing stereoselectivity , 1990 .

[88]  Y. Ohizumi,et al.  Amphidinolide E, a novel antileukemic 19-membered macrolide from the cultured symbiotic dinoflagellate Amphidinium sp. , 1990 .

[89]  S. Sharma,et al.  Scope and mechanism of stannylalumination of 1-alkynes , 1989 .

[90]  J. Stille,et al.  Stereospecific cross-coupling of vinyl halides with vinyl tin reagents catalyzed by palladium , 1987 .

[91]  P. F. Hudrlik,et al.  Stereospecific olefin-forming elimination reactions of .beta.-hydroxyalkylsilanes , 1975 .

[92]  T. Brocksom,et al.  Simple stereoselective version of the Claisen rearrangement leading to trans-trisubstituted olefinic bonds. Synthesis of squalene , 1970 .

[93]  W. Doering,et al.  Sulfur trioxide in the oxidation of alcohols by dimethyl sulfoxide , 1967 .

[94]  Arun K. Ghosh,et al.  Chapter 9 First total synthesis of (+)-Amphidinolide T1 , 2004 .

[95]  Y. Kita,et al.  Novel efficient synthesis of 1-ethoxyvinyl esters using ruthenium catalysts and their use in acylation of amines and alcohols: synthesis of hydrophilic 3′-N-acylated oxaunomycin derivatives , 1993 .

[96]  W. Roush,et al.  Diisopropyl tartrate modified (E)-γ-[(cyclohexyloxy)dimethylsilyl]- and (E)-γ-(dimethylphenylsilyl)allylboronates: Chiral Reagents for the Enantio- and Diastereoselective synthesis of anti 1,2-diols and 2-butene-1,4-diols via the formal α- and γ-hydroxyallylation of aldehydes , 1992 .

[97]  C. Schmid,et al.  2,3-O-(3-Pentylidene)-D-glyceraldehyde and 2,3-O-(3-Pentylidene)-L-glyceraldehyde: Convenient Glyceraldehyde Surrogates Obtained via a Novel Periodate-Based Oxdation System , 1992 .

[98]  K. Horita,et al.  Synthesis of erythronolide a via a very efficient macrolactonization under usual acylation conditions with the Yamaguchi reagent , 1990 .

[99]  W. Roush,et al.  Diisopropyl tartrate (E)-γ-(dimethylphenylsilyl)allylboronate, a chiral allylic alcohol β-carbanion equivalent for the enantioselective synthesis of 2-butene-1,4-diols from aldehydes , 1990 .

[100]  K. Horita,et al.  On the selectivity of deprotection of benzyl, mpm (4-methoxybenzyl) and dmpm (3,4-dimethoxybenzyl) protecting groups for hydroxy functions , 1986 .

[101]  K. Nakanishi,et al.  Circular dichroic spectroscopy : exciton coupling in organic stereochemistry , 1983 .

[102]  H. Mosher,et al.  Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) esters , 1973 .

[103]  E. Corey,et al.  A synthetic method for formyl→ethynyl conversion (RCHO→RCCH or RCCR′) , 1972 .

[104]  J. B. Cohen,et al.  Asymmetric Synthesis , 1904, Nature.