Development of printed and flexible dry ECG electrodes

Abstract Printed, flexible and wearable dry electrodes for monitoring electrocardiogram (ECG) signals, without any skin preparation and use of wet gel, has been developed. Silver (Ag) flake ink was screen printed on a flexible polyethylene terephthalate (PET) substrate to fabricate the dry ECG electrode. Multi-walled carbon nanotube (MWCNT)/polydimethylsiloxane (PDMS) composite, as a conductive polymer, was then deposited on the printed Ag electrode by using a bar coating technique. The performance of the printed electrodes was investigated by testing the MWCNT/PDMS composite conductivity and measuring the electrode-skin impedance for electrode radii varying from 8 mm to 16 mm. It was observed that the dry ECG electrode, with the largest area, demonstrated better performance, in terms of MWCNT/PDMS composite conductivity, ECG signal intensity and correlation when compared to a commercial wet silver/silver chloride (Ag/AgCl) electrode. In addition, the capability of the dry ECG electrodes for monitoring ECG signals in both the relaxed sitting position and while the subject is in motion, was also investigated and the results were compared with a wet Ag/AgCl ECG electrode (T716). While the subject is in motion, the printed dry electrodes were less noisy and were able to better identify the typical ECG characteristics in the signals due to its better conformal contact at the electrode-skin interface. The results obtained demonstrated the feasibility of employing conventional screen printing process for the development of flexible dry ECG electrodes for applications in the biomedical industry.

[1]  N. A. Siddiqui,et al.  DISPERSION AND FUNCTIONALIZATION OF CARBON NANOTUBES FOR POLYMER-BASED NANOCOMPOSITES: A REVIEW , 2010 .

[2]  Jyh-Yeong Chang,et al.  Novel Dry Polymer Foam Electrodes for Long-Term EEG Measurement , 2011, IEEE Transactions on Biomedical Engineering.

[3]  D. Khang,et al.  Electrical and mechanical characterization of stretchable multi-walled carbon nanotubes/polydimethylsiloxane elastomeric composite conductors , 2012 .

[4]  K. Park,et al.  Flexible polymeric dry electrodes for the long-term monitoring of ECG , 2008 .

[5]  Jesse Jur,et al.  Fabric-Based Wearable Dry Electrodes for Body Surface Biopotential Recording , 2016, IEEE Transactions on Biomedical Engineering.

[6]  John G. Webster,et al.  Driven-right-leg circuit design , 1983, IEEE Transactions on Biomedical Engineering.

[7]  Bor-Shyh Lin,et al.  Novel Active Comb-Shaped Dry Electrode for EEG Measurement in Hairy Site , 2015, IEEE Transactions on Biomedical Engineering.

[8]  Alberto J. Palma,et al.  Printed single-chip UHF passive radio frequency identification tags with sensing capability , 2014 .

[9]  Madhuchhanda Mitra,et al.  ECG Acquisition and Automated Remote Processing , 2013 .

[10]  Gert Cauwenberghs,et al.  Integrated Circuits and Electrode Interfaces for Noninvasive Physiological Monitoring , 2014, IEEE Transactions on Biomedical Engineering.

[11]  Yijun Wang,et al.  A Self-Wetting Paper Electrode for Ubiquitous Bio-Potential Monitoring , 2017, IEEE Sensors Journal.

[12]  Yong Zhu,et al.  Wearable silver nanowire dry electrodes for electrophysiological sensing , 2015 .

[13]  B. B. Narakathu,et al.  Novel fully screen printed flexible electrochemical sensor for the investigation of electron transfer between thiol functionalized viologen and gold clusters , 2013 .

[14]  Francis E. H. Tay,et al.  A microfabricated electrode with hollow microneedles for ECG measurement , 2009 .

[15]  Bradley J. Bazuin,et al.  A novel flexographic printed strain gauge on paper platform , 2015, 2015 IEEE SENSORS.

[16]  Eung Je Woo,et al.  Nanofiber Web Textile Dry Electrodes for Long-Term Biopotential Recording , 2013, IEEE Transactions on Biomedical Circuits and Systems.

[17]  Bin Yu,et al.  Bluetooth Low Energy (BLE) based mobile electrocardiogram monitoring system , 2012, 2012 IEEE International Conference on Information and Automation.

[18]  Alex Mihailidis,et al.  Design of a capacitive ECG sensor for unobtrusive heart rate measurements , 2013, 2013 IEEE International Instrumentation and Measurement Technology Conference (I2MTC).

[19]  Conor O'Mahony,et al.  Microneedle-Based Electrodes with Integrated Through-Silicon via for Biopotential Recording , 2012 .

[20]  B. B. Narakathu,et al.  Development of a printed impedance based electrochemical sensor on paper substrate , 2016, 2016 IEEE SENSORS.

[21]  B. B. Narakathu,et al.  Screen Printing of Multilayered Hybrid Printed Circuit Boards on Different Substrates , 2015, IEEE Transactions on Components, Packaging and Manufacturing Technology.

[22]  A. Bermak,et al.  Study of piezoresistance effect of carbon nanotube-PDMS composite materials for nanosensors , 2007, 2007 7th IEEE Conference on Nanotechnology (IEEE NANO).

[23]  Sang-Hoon Lee,et al.  CNT/PDMS Composite Flexible Dry Electrodesfor Long-Term ECG Monitoring , 2012, IEEE Transactions on Biomedical Engineering.

[24]  Ying Meng,et al.  A flexible dry micro-dome electrode for ECG monitoring , 2015 .

[25]  Jos L. Campbell,et al.  A human pilot trial of ingestible electronic capsules capable of sensing different gases in the gut , 2018 .

[26]  Cedric Assambo,et al.  Low-Frequency Response and the Skin-Electrode Interface in Dry-Electrode Electrocardiography , 2012 .

[27]  Hoi-Jun Yoo,et al.  Fabric circuit board-based dry electrode and its characteristics for long-term physiological signal recording , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[28]  P. Supaphol,et al.  Modification of disposable screen-printed carbon electrode surfaces with conductive electrospun nanofibers for biosensor applications , 2013 .

[29]  Yu-Te Wang,et al.  Development of a Wearable Mobile Electrocardiogram Monitoring System by Using Novel Dry Foam Electrodes , 2014, IEEE Systems Journal.

[30]  Jing Quan Liu,et al.  Parylene-based flexible dry electrode for bioptential recording , 2016 .

[31]  Dong-Jun Kim,et al.  Wearable Heart Electrical Activity Monitoring using Circular Ring Electrode , 2007 .

[32]  L. Lorenzelli,et al.  Bendable piezoresistive sensors by screen printing MWCNT/PDMS composites on flexible substrates , 2014, 2014 10th Conference on Ph.D. Research in Microelectronics and Electronics (PRIME).

[33]  Ramon Pallàs-Areny,et al.  AC-coupled front-end for biopotential measurements , 2003, IEEE Transactions on Biomedical Engineering.

[34]  M. Berggren,et al.  Printable All‐Organic Electrochromic Active‐Matrix Displays , 2007 .

[35]  Xuetao Shi,et al.  Performance Evaluation of Five Types of Ag/AgCl Bio-Electrodes for Cerebral Electrical Impedance Tomography , 2011, Annals of Biomedical Engineering.

[36]  X. Ding,et al.  Fabrication of conductive fabric as textile electrode for ECG monitoring , 2014, Fibers and Polymers.

[37]  J. Webster,et al.  Dry electrodes for electrocardiography , 2013, Physiological measurement.

[38]  Julian Hill,et al.  Intestinal Gas Capsules: A Proof-of-Concept Demonstration. , 2016, Gastroenterology.

[39]  Jingquan Liu,et al.  A MEMS-based pyramid micro-needle electrode for long-term EEG measurement , 2013 .

[40]  John G. Webster,et al.  Medical Instrumentation: Application and Design , 1997 .

[41]  Longchun Wang,et al.  PDMS-Based Low Cost Flexible Dry Electrode for Long-Term EEG Measurement , 2012, IEEE Sensors Journal.

[42]  Jin-Woo Choi,et al.  Patterning conductive PDMS nanocomposite in an elastomer using microcontact printing , 2009 .

[43]  Edward Grant,et al.  Fabric-Based Active Electrode Design and Fabrication for Health Monitoring Clothing , 2009, IEEE Transactions on Information Technology in Biomedicine.

[44]  Enric Cabruja,et al.  Carbon nanotube/polysulfone composite screen-printed electrochemical enzyme biosensors. , 2007, In Analysis.

[45]  B. B. Narakathu,et al.  Development of a novel carbon nanotube based printed and flexible pressure sensor , 2017, 2017 IEEE Sensors Applications Symposium (SAS).

[46]  Xianting Ding,et al.  A modularized and flexible sensor based on MWCNT/PDMS composite film for on-site electrochemical analysis , 2017 .

[47]  Jing Liu,et al.  Biomedical Implementation of Liquid Metal Ink as Drawable ECG Electrode and Skin Circuit , 2013, PloS one.

[48]  Colette Lacabanne,et al.  DC and AC conductivity of carbon nanotubes-polyepoxy composites , 2003 .