Identification of shikonin and its ester derivatives from the roots of Echium italicum L.

[1]  S. Bhushan,et al.  Isolation and purification of acetylshikonin and beta-acetoxyisovalerylshikonin from cell suspension cultures of Arnebia euchroma (Royle) Johnston using rapid preparative HPLC. , 2008, Journal of separation science.

[2]  Kaishun Bi,et al.  Antioxidants from a Chinese medicinal herb – Lithospermum erythrorhizon , 2008 .

[3]  M. Bolognesi,et al.  A new EGFR inhibitor induces apoptosis in colon cancer cells. , 2007, Biochemical and biophysical research communications.

[4]  H. Stuppner,et al.  Determination of naphthazarin derivatives in endemic Turkish Alkanna species by reversed phase high performance liquid chromatography. , 2007, Planta medica.

[5]  A. Assimopoulou,et al.  Analysis of alkannin derivatives from Alkanna species by high-performance liquid chromatography/photodiode array/mass spectrometry. , 2006, Biomedical chromatography : BMC.

[6]  Zhong-Zhen Zhao,et al.  Simultaneous determination of naphthoquinone derivatives in Boraginaceous herbs by high-performance liquid chromatography. , 2006, Analytica chimica acta.

[7]  Zhaoqing Xu,et al.  A Novel Total Synthesis of (±) Shikonin , 2006 .

[8]  A. Assimopoulou,et al.  Study on the enantiomeric ratio of the pharmaceutical substances alkannin and shikonin. , 2004, Biomedical chromatography : BMC.

[9]  A. Assimopoulou,et al.  Study on polymerization of the pharmaceutical substances isohexenylnaphthazarins. , 2004, Biomedical chromatography : BMC.

[10]  A. Assimopoulou,et al.  Study on isohexenylnaphthazarins polymerization in alkaline media. , 2004, Biomedical chromatography : BMC.

[11]  D. Boskou,et al.  Antioxidant activities of alkannin, shikonin and Alkanna tinctoria root extracts in oil substrates , 2004 .

[12]  B. Czako,et al.  Formal total synthesis of shikonin via Dötz benzannulation , 2004 .

[13]  Feng Chen,et al.  Preparative high-speed counter-current chromatography for purification of shikonin from the Chinese medicinal plant Lithospermum erythrorhizon. , 2004, Journal of chromatography. A.

[14]  S. A. Fedoreev,et al.  Quinoid pigments of far eastern representatives of the family Boraginaceae , 1979, Chemistry of Natural Compounds.

[15]  Jian Ding,et al.  Shikonin derivatives: synthesis and inhibition of human telomerase. , 2002, Bioorganic & medicinal chemistry letters.

[16]  A. Srivastava,et al.  New naphthoquinones from Arnebia hispidissima roots. , 2001, Planta medica.

[17]  V. Denisenko,et al.  Shikonin production by p-fluorophenylalanine resistant cells of Lithospermum erythrorhizon. , 2001, Fitoterapia.

[18]  J. Oppenheim,et al.  Shikonin, a component of antiinflammatory Chinese herbal medicine, selectively blocks chemokine binding to CC chemokine receptor-1. , 2001, International immunopharmacology.

[19]  H. Sakurai,et al.  Reaction of β-Alkannin (Shikonin) with Reactive Oxygen Species: Detection of β-Alkannin Free Radicals , 2000 .

[20]  Weng Xinchu,et al.  Antioxidant properties of components extracted from puccoon (Lithospermum erythrorhizon Sieb. et Zucc.). , 2000 .

[21]  H. Yamamoto,et al.  Simultaneous analysis of shikimate-derived secondary metabolites in Lithospermum erythrorhizon cell suspension cultures by high-performance liquid chromatography. , 2000, Journal of chromatography. B, Biomedical sciences and applications.

[22]  T. Hahn,et al.  Physical stability of shikonin derivatives from the roots of Lithospermum erythrorhizon cultivated in Korea. , 1999, Journal of agricultural and food chemistry.

[23]  T. Zhou,et al.  Studies on in vitro metabolism of shikonin , 1999, Phytotherapy research : PTR.

[24]  K. Nicolaou,et al.  The Chemistry and Biology of Alkannin, Shikonin, and Related Naphthazarin Natural Products. , 1999, Angewandte Chemie.

[25]  Flores,et al.  Cell-specific production and antimicrobial activity of naphthoquinones in roots of lithospermum erythrorhizon , 1999, Plant physiology.

[26]  A. Assimopoulou,et al.  Use of matrix‐assisted laser desorption/ionization mass spectrometry for the rapid detection of low‐mass components in the Alkanna tinctoria pigments fraction , 1998 .

[27]  E. Couladouros,et al.  Asymmetric synthesis of alkannin and shikonin , 1997 .

[28]  K. Başer,et al.  Quantitative determination of naphthaquinones of Arnebia densiflora (Nordm.) Ledeb. by an improved high-performance liquid chromatographic method , 1997 .

[29]  E. Yeşilada,et al.  Quantitative analysis of the enantiomeric naphthaquinone derivatives from Boraginaceous roots by high performance liquid chromatography , 1996 .

[30]  S. Kuo,et al.  Inhibition on platelet activation by shikonin derivatives isolated from Arnebia euchroma. , 1995, Biochimica et biophysica acta.

[31]  H. Cheng,et al.  Photochemical decomposition of alkannin/shikonin enantiomers , 1995 .

[32]  K. Yazaki,et al.  Isolation of deoxyshikonin, an antidermatophytic principle from Lithospermum erythrorhizon cell cultures. , 1988, Journal of natural products.

[33]  M. Tabata,et al.  A comparative study on anti-inflammatory activities of the enantiomers, shikonin and alkannin. , 1986, Journal of natural products.

[34]  H. Mizukami,et al.  Formation of stereoisomeric mixtures of naphthoquinone derivatives in Echium lycopsis callus cultures , 1983 .

[35]  V. Papageorgiou Naturally occurring isohexenylnaphthazarin pigments: a new class of drugs. , 1980, Planta medica.

[36]  V. Papageorgiou,et al.  Studies on the relationship of structure to antimicrobial properties of naphthaquinones and other constituents of Alkanna tinctoria. , 1979, Planta medica.