SERRS dyes. Part I. Synthesis of benzotriazole monoazo dyes as model analytes for surface enhanced resonance Raman scattering.

The synthesis of seven monoazo benzotriazole dyes for use in surface enhanced resonance Raman scattering, SERRS, is reported. The dyes are all capable of complexing to the silver surface used to provide the surface enhancement found in SERRS and hence act as 'model' analytes. One dye was examined in detail and showed a quantitative relationship between concentration and signal intensity.

[1]  T. Cotton,et al.  Determination of purine bases by reversed-phase high-performance liquid chromatography using real-time surface-enhanced Raman spectroscopy , 1991 .

[2]  A. Wokaun,et al.  Surface‐enhanced resonance Raman scattering study of the groove binding dye hoechst 33258 , 1995 .

[3]  A. Munro,et al.  Fatty acid-induced alteration of the porphyrin macrocycle of cytochrome P450 BM3. , 1998, Biophysical journal.

[4]  Parr,et al.  Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. , 1988, Physical review. B, Condensed matter.

[5]  S. Teat,et al.  The synthesis and first full structural elucidation of a benzotriazole azo dye , 2000 .

[6]  Duncan Graham,et al.  Selective detection of deoxyribonucleic acid at ultralow concentrations by SERRS , 1997 .

[7]  I. Nabiev,et al.  DNA Binding by Fagaronine and Ethoxidine, Inhibitors of Human DNA Topoisomerases I and II, Probed by SERS and Flow Linear Dichroism Spectroscopy † , 1999 .

[8]  Guangming Zhou.  Sers Studies on a Novel Copper Porphyrin and Its Complex with DNA , 1998 .

[9]  C. Nguyen,et al.  Molecular interactions of DNA-topoisomerase I and II inhibitor with DNA and topoisomerases and in ternary complexes: binding modes and biological effects for intoplicine derivatives. , 1994, Biochemistry.

[10]  P. White,et al.  Characterization of the Surface of a Citrate-Reduced Colloid Optimized for Use as a Substrate for Surface-Enhanced Resonance Raman Scattering , 1995 .

[11]  W. Kiefer,et al.  Raman and surface enhanced Raman spectroscopy of 2,2,5,5-tetramethyl-3-pyrrolin-1-yloxy-3-carboxamide labeled proteins: bovine serum albumin and cytochrome c. , 2001, Biopolymers.

[12]  Duncan Graham,et al.  Surface‐Enhanced Resonance Raman Scattering as a Novel Method of DNA Discrimination , 2000 .

[13]  D. Meisel,et al.  Adsorption and surface-enhanced Raman of dyes on silver and gold sols , 1982 .

[14]  A. Becke,et al.  Density-functional exchange-energy approximation with correct asymptotic behavior. , 1988, Physical review. A, General physics.