Stroke management and the impact of mobile stroke treatment units

Stroke remains the fifth leading cause of death in the United States, despite declining morbidity and mortality rates. Patients who receive timely care provided by mobile stroke treatment unit staffs have dramatically improved outcomes compared with patients who receive initial treatment in an emergency department. Portable imaging technology and wireless communication devices have contributed significantly to shorter time to treatment, which is a key factor in improved outcomes.

[1]  S. Oparil,et al.  Is Blood Pressure Control for Stroke Prevention the Correct Goal?: The Lost Opportunity of Preventing Hypertension , 2015, Stroke.

[2]  Shyam Prabhakaran,et al.  Acute stroke intervention: a systematic review. , 2015, JAMA.

[3]  Eli Segal,et al.  Effect of the use of ambulance-based thrombolysis on time to thrombolysis in acute ischemic stroke: a randomized clinical trial. , 2015, CJEM.

[4]  M. Ebinger,et al.  Improved Prehospital Triage of Patients With Stroke in a Specialized Stroke Ambulance: Results of the Pre-Hospital Acute Neurological Therapy and Optimization of Medical Care in Stroke Study , 2015, Stroke.

[5]  F. Briggs,et al.  Abstract T P200: Feasibility of Telemedicine on a Mobile Stroke Treatment Unit , 2015 .

[6]  M. Stecker,et al.  Abstract W P31: Does Portable CT Imaging in a Mobile Stroke Treatment Unit (MSTU) Provide Adequate Quality for Early Critical Decision Making? , 2015 .

[7]  Andrew P. Reimer,et al.  Abstract 54: Reduction in time to Imaging and intravenous Thrombolysis by in-field Evaluation and Treatment in a Mobile Stroke Treatment Unit , 2015 .

[8]  M. Mittal,et al.  Neighborhood socioeconomic status and stroke mortality: Disentangling individual and area effects , 2013, Neurology.

[9]  Adrian F Hernandez,et al.  Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic stroke. , 2013, JAMA.

[10]  W. Powers,et al.  Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association , 2013, Stroke.

[11]  Geoff Cohen,et al.  Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis , 2012, The Lancet.

[12]  Klaus Fassbender,et al.  Diagnosis and treatment of patients with stroke in a mobile stroke unit versus in hospital: a randomised controlled trial , 2012, The Lancet Neurology.

[13]  R. Hornung,et al.  Recombinant Tissue-Type Plasminogen Activator Use for Ischemic Stroke in the United States: A Doubling of Treatment Rates Over the Course of 5 Years , 2011, Stroke.

[14]  Gregory W Albers,et al.  Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials , 2010, The Lancet.

[15]  L. Goldstein,et al.  Hospital Arrival Time and Intravenous t-PA Use in US Academic Medical Centers, 2001–2004 , 2009, Stroke.

[16]  Mark D. Huffman,et al.  Heart Disease and Stroke Statistics—2015 Update: A Report From the American Heart Association , 2009, Circulation.

[17]  M. Kaste,et al.  Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. , 2008, The New England journal of medicine.

[18]  J. Saver Time Is Brain—Quantified , 2006, Stroke.

[19]  Scott Hamilton,et al.  Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials , 2004, The Lancet.

[20]  Joseph P. Broderick,et al.  Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. , 1995 .

[21]  Michal Rozanski,et al.  Effects of golden hour thrombolysis: a Prehospital Acute Neurological Treatment and Optimization of Medical Care in Stroke (PHANTOM-S) substudy. , 2015, JAMA neurology.

[22]  Prevalence of stroke--United States, 2006-2010. , 2012, MMWR. Morbidity and mortality weekly report.

[23]  Paul E. Schulz,et al.  Why are stroke patients excluded from tPA therapy? An analysis of patient eligibility , 2001 .