EXPERIMENTAL INFECTION IN THE RABBIT WITH TRICHOSPORON CAPITATUM

Gilbert, Walter R., Jr. (Duke University Medical Center, Durham, N.C.) and Bernard F. Fetter. Experimental infection in the rabbit with Trichosporon capitatum. J. Bacteriol. 84:961–966. 1962.—Fifteen New Zealand white rabbits were inoculated intravenously with a saline suspension of spores and hyphal fragments of Trichosporon capitatum. Nine of the animals succumbed spontaneously. The others were sacrificed at varying intervals. Autopsies revealed mycotic abscesses in the kidneys, which ruptured through into the tubules. The fungus also invaded the brain and heart, where it evoked a mixed reaction. The organism was recovered from the animals at the time of autopsy.