Studies on Chemical Constituents in Swertia mussotii Franch

As a continuation of our studies on chemical constituents of Swertia plant,from the over-ground parts of Swertia mussotii Franch which is a traditional Tibetan medicine,eight compounds,1,2,6-Trimethoxy-8-hydroxyxanthone(1),1,3-Dimethoxy-8-hydroxyxanthone(2),(z)-5-Ethylidene-3,4,5,6-tetrahydro-cis-6,8-dimethoxy-1H,8H-pyrano-pyran-1-one(3),swertiamarin(4),gentiopicroside(5),Sweroside(6),Stigmasterol(7) and β-sitosterol(8),were isolated.Their structures were determined by using conventional spectroscopic methods.Compound 3 was isolated from the genus for the first time.The effect of compound 1 on aldose reductase was 18.3%(10-5 mol/L).