Molecular links between obesity and breast cancer.
暂无分享,去创建一个
[1] Roger B. Davis,et al. Obesity and breast cancer screening , 2004, Journal of General Internal Medicine.
[2] P. Simpson,et al. Obesity promotes 7,12-dimethylbenz(a)anthracene-induced mammary tumor development in female zucker rats , 2005, Breast Cancer Research.
[3] T. Kadowaki,et al. Adiponectin and adiponectin receptors. , 2005, Endocrine reviews.
[4] Adrian V. Lee,et al. Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor. , 2005, Cancer research.
[5] B. Nicklas,et al. Abdominal adipose tissue cytokine gene expression: relationship to obesity and metabolic risk factors. , 2005, American journal of physiology. Endocrinology and metabolism.
[6] R. Frairia,et al. Sex hormone-binding globulin antagonizes the anti-apoptotic effect of estradiol in breast cancer cells , 2005, Molecular and Cellular Endocrinology.
[7] J. Carroll,et al. Estrogen and insulin/IGF-1 cooperatively stimulate cell cycle progression in MCF-7 breast cancer cells through differential regulation of c-Myc and cyclin D1 , 2005, Molecular and Cellular Endocrinology.
[8] D. Timmerman,et al. Third generation aromatase inhibitors may prevent endometrial growth and reverse tamoxifen-induced uterine changes in postmenopausal breast cancer patients. , 2005, Annals of oncology : official journal of the European Society for Medical Oncology.
[9] C. Shimizu,et al. Expression of insulin-like growth factor 1 receptor in primary breast cancer: immunohistochemical analysis. , 2004, Human pathology.
[10] E. Surmacz,et al. Leptin Interferes with the Effects of the Antiestrogen ICI 182,780 in MCF-7 Breast Cancer Cells , 2004, Clinical Cancer Research.
[11] F. Clavel-Chapelon,et al. Body size and breast cancer risk: Findings from the European prospective investigation into cancer and nutrition (EPIC) , 2004, International journal of cancer.
[12] C. Meisinger,et al. The relationship between body weight and health care among German women. , 2004, Obesity research.
[13] D. Jacobs,et al. Serum adiponectin in young adults--interactions with central adiposity, circulating levels of glucose, and insulin resistance: the CARDIA study. , 2004, Annals of epidemiology.
[14] D. Rose,et al. Obesity, adipocytokines, and insulin resistance in breast cancer , 2004, Obesity reviews : an official journal of the International Association for the Study of Obesity.
[15] P. Stattin,et al. Plasma Leptin and Breast Cancer Risk: A Prospective Study in Northern Sweden , 2004, Breast Cancer Research and Treatment.
[16] H. Nagawa,et al. Enhanced Expression of Leptin and Leptin Receptor (OB-R) in Human Breast Cancer , 2004, Clinical Cancer Research.
[17] L. Tessitore,et al. Adipocyte expression and circulating levels of leptin increase in both gynaecological and breast cancer patients. , 2004, International journal of oncology.
[18] A. Goldhirsch,et al. Body mass index as a prognostic feature in operable breast cancer: the International Breast Cancer Study Group experience. , 2004, Annals of oncology : official journal of the European Society for Medical Oncology.
[19] C. Giordano,et al. Leptin Induces, via ERK1/ERK2 Signal, Functional Activation of Estrogen Receptor α in MCF-7 Cells* , 2004, Journal of Biological Chemistry.
[20] J. E. Hewett,et al. Leptin expression in breast nipple aspirate fluid (NAF) and serum is influenced by body mass index (BMI) but not by the presence of breast cancer. , 2004, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[21] R. Weinberg,et al. Reconstruction of functionally normal and malignant human breast tissues in mice. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[22] S. Twigg,et al. Insulin-Like Growth Factor-Binding Protein 3 Induces Caspase-Dependent Apoptosis through a Death Receptor-Mediated Pathway in MCF-7 Human Breast Cancer Cells , 2004, Cancer Research.
[23] C. Mantzoros,et al. Adiponectin and breast cancer risk. , 2004, The Journal of clinical endocrinology and metabolism.
[24] S. Kihara,et al. Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[25] Adrian V. Lee,et al. A Dominant Negative Type I Insulin-like Growth Factor Receptor Inhibits Metastasis of Human Cancer Cells* , 2004, Journal of Biological Chemistry.
[26] J. Grande,et al. Leptin Receptor-Deficient MMTV-TGF-α/Leprdb Leprdb Female Mice Do Not Develop Oncogene-Induced Mammary Tumors , 2004 .
[27] Z. Djuric,et al. Improvement of metabolism among obese breast cancer survivors in differing weight loss regimens. , 2004, Obesity research.
[28] Claude Lenfant,et al. Definition of Metabolic Syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[29] P. Trayhurn,et al. Regulation of haptoglobin gene expression in 3T3-L1 adipocytes by cytokines, catecholamines, and PPARgamma. , 2004, Biochemical and biophysical research communications.
[30] R. Shore,et al. Postmenopausal levels of oestrogen, androgen, and SHBG and breast cancer: long-term results of a prospective study , 2004, British Journal of Cancer.
[31] T. Key,et al. Lifestyle determinants of serum insulin-like growth-factor-I (IGF-I), C-peptide and hormone binding protein levels in British women , 2003, Cancer Causes & Control.
[32] J. Grande,et al. Genetically Obese MMTV-TGF-α/LepobLepob Female Mice do not Develop Mammary Tumors , 2003, Breast Cancer Research and Treatment.
[33] J. Grande,et al. Leptin receptor-deficient MMTV-TGF-alpha/Lepr(db)Lepr(db) female mice do not develop oncogene-induced mammary tumors. , 2004, Experimental biology and medicine.
[34] O. Dizdar,et al. Obesity: an endocrine tumor? , 2004, Medical hypotheses.
[35] C. Giordano,et al. Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor alpha in MCF-7 cells. , 2004, The Journal of biological chemistry.
[36] Adrian V. Lee,et al. Crosstalk Between the Insulin-Like Growth Factors and Estrogens in Breast Cancer , 2004, Journal of Mammary Gland Biology and Neoplasia.
[37] I. G. Fantus,et al. Insulin and related factors in premenopausal breast cancer risk , 2004, Breast Cancer Research and Treatment.
[38] A. Folsom,et al. Intentional weight loss and incidence of obesity-related cancers: the Iowa Women's Health Study , 2003, International Journal of Obesity.
[39] S. Kihara,et al. Association of serum adiponectin levels with breast cancer risk. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[40] G. Hotamisligil,et al. Inflammatory pathways and insulin action , 2003, International Journal of Obesity.
[41] S. Toda,et al. Mature adipocytes, but not preadipocytes, promote the growth of breast carcinoma cells in collagen gel matrix culture through cancer–stromal cell interactions , 2003, The Journal of pathology.
[42] D. Roith. The Insulin-Like Growth Factor System , 2003, Experimental Diabesity Research.
[43] Puneeth Iyengar,et al. Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization , 2003, Oncogene.
[44] M. Pignatelli,et al. Enhancement of BRCA1 gene expression by the peroxisome proliferator-activated receptor γ in the MCF-7 breast cancer cell line , 2003, Oncogene.
[45] L. Bernstein,et al. Effect of family history, obesity and exercise on breast cancer risk among postmenopausal women , 2003, International journal of cancer.
[46] C. Giordano,et al. Leptin Enhances, via AP-1, Expression of Aromatase in the MCF-7 Cell Line* , 2003, Journal of Biological Chemistry.
[47] Philippe Froguel,et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects , 2003, Nature.
[48] JoAnn E Manson,et al. Type 2 diabetes and subsequent incidence of breast cancer in the Nurses' Health Study. , 2003, Diabetes care.
[49] J. Blay,et al. Prognostic value of serum levels of interleukin 6 and of serum and plasma levels of vascular endothelial growth factor in hormone-refractory metastatic breast cancer patients , 2003, British Journal of Cancer.
[50] F. Gilliland,et al. Adiposity and sex hormones in postmenopausal breast cancer survivors. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[51] Michael J Thun,et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. , 2003, The New England journal of medicine.
[52] P. Garcia-Lorda,et al. Systemic inflammation, adipose tissue tumor necrosis factor, and leptin expression. , 2003, Obesity research.
[53] R. Paschke,et al. Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes. , 2003, Biochemical and biophysical research communications.
[54] L. V. Van Gaal,et al. Leptin levels in type 2 diabetes: associations with measures of insulin resistance and insulin secretion. , 2003, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[55] J. Grande,et al. Genetically obese MMTV-TGF-alpha/Lep(ob)Lep(ob) female mice do not develop mammary tumors. , 2003, Breast cancer research and treatment.
[56] Xin Hu,et al. Leptin--a growth factor in normal and malignant breast cells and for normal mammary gland development. , 2003, Journal of the National Cancer Institute.
[57] C. Mantzoros,et al. The Role of the IGF System in Cancer: From Basic to Clinical Studies and Clinical Applications , 2002, Oncology.
[58] A. Purohit,et al. Regulation of estrogen synthesis in postmenopausal women , 2002, Steroids.
[59] F. Berrino,et al. Fasting glucose is a risk factor for breast cancer: a prospective study. , 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[60] S. Uchida,et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase , 2002, Nature Medicine.
[61] K. Yasuda,et al. Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: reciprocal involvement of PKC-alpha and PPAR expression. , 2002, Biochimica et biophysica acta.
[62] F. Berrino,et al. Circulating levels of insulin‐like growth factor‐I and risk of ovarian cancer , 2002, International journal of cancer.
[63] M. Hanefeld,et al. Insulin-resistant patients with type 2 diabetes mellitus have higher serum leptin levels independently of body fat mass , 2002, Acta Diabetologica.
[64] A. Folsom,et al. Serum insulin and glucose levels and breast cancer incidence: the atherosclerosis risk in communities study. , 2002, American journal of epidemiology.
[65] D. Yee,et al. Insulin-like growth factor binding protein-1 (IGFBP-1) inhibits breast cancer cell motility. , 2002, Cancer research.
[66] S. Kihara,et al. Adipocyte-Derived Plasma Protein Adiponectin Acts as a Platelet-Derived Growth Factor-BB–Binding Protein and Regulates Growth Factor–Induced Common Postreceptor Signal in Vascular Smooth Muscle Cell , 2002, Circulation.
[67] J. Carroll,et al. Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens. , 2002, Cancer research.
[68] M. Dieudonné,et al. Leptin mediates a proliferative response in human MCF7 breast cancer cells. , 2002, Biochemical and biophysical research communications.
[69] J. Jansson,et al. Intracerebroventricular interleukin-6 treatment decreases body fat in rats. , 2002, Biochemical and biophysical research communications.
[70] T. Key,et al. Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies. , 2002, Journal of the National Cancer Institute.
[71] S. O’Rahilly,et al. Induction of Adipocyte Complement-related Protein of 30 Kilodaltons by Ppar␥ Agonists: a Potential Mechanism of Insulin Sensitization , 2022 .
[72] J. Peyrat,et al. Identification of leptin receptors in human breast cancer: functional activity in the T47-D breast cancer cell line , 2002, Molecular and Cellular Endocrinology.
[73] A. Purohit,et al. The role of cytokines in regulating estrogen synthesis: implications for the etiology of breast cancer , 2002, Breast Cancer Research.
[74] B. Hoffman,et al. Fasting insulin and outcome in early-stage breast cancer: results of a prospective cohort study. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[75] S. O’Rahilly,et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization. , 2002, Endocrinology.
[76] D. Yee,et al. Regulation of breast cancer cell motility by insulin receptor substrate-2 (IRS-2) in metastatic variants of human breast cancer cell lines , 2001, Oncogene.
[77] S. Coppack. Pro-inflammatory cytokines and adipose tissue , 2001, Proceedings of the Nutrition Society.
[78] C Bogardus,et al. Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion. , 2001, Obesity Research.
[79] J. Dupont,et al. Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: new insights into their synergistic effects , 2001, Molecular pathology : MP.
[80] M. C. Archer,et al. Susceptibility of lean and obese Zucker rats to tumorigenesis induced by N-methyl-N-nitrosourea. , 2001, Cancer letters.
[81] D. Yee,et al. The IGF system and breast cancer. , 2001, Endocrine-related cancer.
[82] J R Marshall,et al. Pooled analysis of prospective cohort studies on height, weight, and breast cancer risk. , 2000, American journal of epidemiology.
[83] S. Kihara,et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. , 2000, Blood.
[84] M. van Eickels,et al. Estrogen Receptor α Rapidly Activates the IGF-1 Receptor Pathway* , 2000, The Journal of Biological Chemistry.
[85] F. May,et al. Insulin Receptor Substrate-1 Expression Is Regulated by Estrogen in the MCF-7 Human Breast Cancer Cell Line* , 2000, The Journal of Biological Chemistry.
[86] A. Zallone,et al. Breast cancer cell line MDA-231 stimulates osteoclastogenesis and bone resorption in human osteoclasts. , 2000, Biochemical and biophysical research communications.
[87] D. Yee,et al. Tyrosine kinase signalling in breast cancer: Insulin-like growth factors and their receptors in breast cancer , 2000, Breast Cancer Research.
[88] J. Marks,et al. Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis. , 2000, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[89] G. Löffler,et al. Influences of Ionomycin, Dibutyryl-cycloAMP and Tumour Necrosis Factor-alpha on Intracellular Amount and Secretion of apM1 in Differentiating Primary Human Preadipocytes , 2000, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[90] R. Frairia,et al. Estradiol induction of cAMP in breast cancer cells is mediated by foetal calf serum (FCS) and sex hormone-binding globulin (SHBG) , 1999, The Journal of Steroid Biochemistry and Molecular Biology.
[91] A. Bilancio,et al. Non‐transcriptional action of oestradiol and progestin triggers DNA synthesis , 1999, The EMBO journal.
[92] M. Dieudonné,et al. In vivo and in vitro ob gene expression and leptin secretion in rat adipocytes: evidence for a regional specific regulation by sex steroid hormones. , 1999 .
[93] C. Davio,et al. An experimental model of diabetes and cancer in rats. , 1998, European journal of cancer.
[94] D. Yee,et al. Insulin Receptor Substrate-1 is the Predominant Signaling Molecule Activated by Insulin-like Growth Factor-I, Insulin, and Interleukin-4 in Estrogen Receptor-positive Human Breast Cancer Cells* , 1998, The Journal of Biological Chemistry.
[95] D. Heber,et al. Preadipocytes stimulate breast cancer cell growth. , 1998, Nutrition and cancer.
[96] S. O’Rahilly,et al. Congenital leptin deficiency is associated with severe early-onset obesity in humans , 1997, Nature.
[97] W. Willett,et al. Body size and risk of breast cancer. , 1997, American journal of epidemiology.
[98] A. Howell,et al. Type I insulin-like growth factor receptor gene expression in normal human breast tissue treated with oestrogen and progesterone. , 1997, British Journal of Cancer.
[99] C. Mantzoros,et al. Role of leptin in the neuroendocrine response to fasting , 1996, Nature.
[100] R. Considine,et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. , 1996, The New England journal of medicine.
[101] R. Frairia,et al. Sex steroid binding protein exerts a negative control on estradiol action in MCF-7 cells (human breast cancer) through cyclic adenosine 3',5'-monophosphate and protein kinase A. , 1996, Endocrinology.
[102] B. Lowell,et al. Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action , 1995, Nature Medicine.
[103] E. Ravussin,et al. Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects , 1995, Nature Medicine.
[104] S. Bulun,et al. Aromatase gene expression in adipose tissue: Relationship to breast cancer , 1994, The Journal of Steroid Biochemistry and Molecular Biology.
[105] B. Spiegelman,et al. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. , 1993, Science.
[106] P. Johnston,et al. Identification of a protein factor secreted by 3T3-L1 preadipocytes inhibitory for the human MCF-7 breast cancer cell line. , 1992, Cancer research.
[107] L. Brinton,et al. Height and weight at various ages and risk of breast cancer. , 1992, Annals of epidemiology.
[108] D. Kerr,et al. The response of breast cancer cells to steroid and peptide growth factors. , 1992, Anticancer research.
[109] B. Elliott,et al. Capacity of adipose tissue to promote growth and metastasis of a murine mammary carcinoma: Effect of estrogen and progesterone , 1992, International journal of cancer.
[110] J. Crave,et al. Pathophysiology of sex hormone binding globulin (SHBG): Relation to insulin , 1991, The Journal of Steroid Biochemistry and Molecular Biology.
[111] P. Watson,et al. Inhibition of c-myc expression by phosphorothioate antisense oligonucleotide identifies a critical role for c-myc in the growth of human breast cancer. , 1991, Cancer research.
[112] P. Taylor,et al. Association of change in body mass with breast cancer. , 1990, Cancer research.
[113] A. V. Landeghem,et al. Endogenous concentration and subcellular distribution of estrogens in normal and malignant human breast tissue. , 1985, Cancer research.
[114] F. Grantham,et al. Role of hormones in the growth and regression of human breast cancer cells (MCF-7) transplanted into athymic nude mice. , 1981, Journal of the National Cancer Institute.
[115] P. Siiteri,et al. Source of estrogen production in postmenopausal women. , 1973, The Journal of clinical endocrinology and metabolism.