Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene

[1]  E. Beutler,et al.  Identification of the second common Jewish Gaucher disease mutation makes possible population-based screening for the heterozygous state. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[2]  R. Bronson,et al.  Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene , 1991, Cell.

[3]  M. Horowitz,et al.  Acid β-Glucosidase: Enzymology and Molecular Biology of Gaucher Diseas , 1990 .

[4]  R. Brady,et al.  Comparison of the chromosomal localization of murine and human glucocerebrosidase genes and of the deduced amino acid sequences. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[5]  Charles R.scriver,et al.  The Metabolic basis of inherited disease , 1989 .

[6]  E. Ginns,et al.  Gaucher's disease: advances and challenges. , 1989, Advances in pediatrics.

[7]  M. Capecchi.  The new mouse genetics: altering the genome by gene targeting. , 1989, Trends in genetics : TIG.

[8]  Mario R. Capecchi,et al.  Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes , 1988, Nature.

[9]  R. Willemsen,et al.  An immunoelectron microscopic study of glucocerebrosidase in type 1 Gaucher's disease spleen. , 1988, Ultrastructural pathology.

[10]  S. Tsuji,et al.  Genetic heterogeneity in type 1 Gaucher disease: multiple genotypes in Ashkenazic and non-Ashkenazic individuals. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[11]  M. Monk,et al.  HPRT-deficient (Lesch–Nyhan) mouse embryos derived from germline colonization by cultured cells , 1987, Nature.

[12]  S. Tsuji,et al.  A mutation in the human glucocerebrosidase gene in neuronopathic Gaucher's disease. , 1987, The New England journal of medicine.

[13]  A. Bradley,et al.  A potential animal model for Lesch–Nyhan syndrome through introduction of HPRT mutations into mice , 1987, Nature.

[14]  E. Robertson.  Teratocarcinomas and embryonic stem cells : a practical approach , 1987 .

[15]  A. Bradley,et al.  Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector , 1986, Nature.

[16]  S. Panny,et al.  Hydrops fetalis associated with Gaucher disease. , 1984, Pathology, research and practice.

[17]  Ian Cooper.  HODGKIN'S DISEASE , 1977, The Medical journal of Australia.

[18]  E. Beutler,et al.  Detection of the defect of Gaucher's disease and its carrier state in peripheral-blood leucocytes. , 1970, Lancet.