Treatment of acute lymphoblastic leukemia in low- and middle-income countries: Challenges and opportunities

Paediatric acute lymphoblastic leukemia (ALL), which affects about 40 children per million below the age of 15 years [1], is highly curable with contemporary widely available treatment approaches. ...

[1]  C. Pui,et al.  Ponte di Legno Working Group: statement on the right of children with leukemia to have full access to essential treatment and report on the Sixth International Childhood Acute Lymphoblastic Leukemia Workshop , 2004, Leukemia.

[2]  J. Burchenal,et al.  Treatment of acute lymphoblastic leukemia. , 1972, Annual review of medicine.

[3]  Kevin C Oeffinger,et al.  Chronic health conditions in adult survivors of childhood cancer. , 2006, The New England journal of medicine.

[4]  C. Pui,et al.  Childhood central nervous system leukemia: historical perspectives, current therapy, and acute neurological sequelae , 2007, Neuroradiology.

[5]  Elaine Coustan-Smith,et al.  A simplified flow cytometric assay identifies children with acute lymphoblastic leukemia who have a superior clinical outcome. , 2006, Blood.

[6]  F. Cavalli,et al.  North-South twinning in paediatric haemato-oncology: the La Mascota programme, Nicaragua , 1998, The Lancet.

[7]  C. Pui,et al.  Outcome of childhood acute lymphoblastic leukaemia in resource-poor countries , 2003, The Lancet.

[8]  Huijun Zhao,et al.  Clinical outcome of children with newly diagnosed acute lymphoblastic leukemia treated in a single center in Shanghai, China , 2008, Leukemia & lymphoma.

[9]  G. Tognoni,et al.  AMOR: A proposed cooperative effort to improve outcomes of childhood cancer in Central America , 2005, Pediatric blood & cancer.

[10]  F. Behm,et al.  Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia. , 1991, The New England journal of medicine.

[11]  C. Pui,et al.  Establishment of a pediatric oncology program and outcomes of childhood acute lymphoblastic leukemia in a resource-poor area. , 2004, JAMA.

[12]  E. Steliarova-Foucher,et al.  My child matters program: A UICC-sanofi-aventis partnership to improve pediatric cancer care in developing countries , 2007 .

[13]  M. Relling,et al.  Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia. , 2003, The New England journal of medicine.

[14]  J. Downing,et al.  Acute Lymphoblastic Leukemia in a Developing Country: Preliminary Results of a Nonrandomized Clinical Trial in El Salvador , 2000, Journal of pediatric hematology/oncology.

[15]  C. Pui,et al.  Saving the children--improving childhood cancer treatment in developing countries. , 2005, The New England journal of medicine.