Visfatin in adipocytes is upregulated by hypoxia through HIF1alpha-dependent mechanism.

[1]  M. Wolzt,et al.  Increased plasma visfatin concentrations in morbidly obese subjects are reduced after gastric banding. , 2006, The Journal of clinical endocrinology and metabolism.

[2]  M. Laakso,et al.  Visfatin is an adipokine, but it is not regulated by thiazolidinediones. , 2006, The Journal of clinical endocrinology and metabolism.

[3]  M. Fasshauer,et al.  Plasma visfatin concentrations and fat depot-specific mRNA expression in humans. , 2005, Diabetes.

[4]  P. Trayhurn.  Endocrine and signalling role of adipose tissue: new perspectives on fat. , 2005, Acta physiologica Scandinavica.

[5]  Jean-Daniel Zucker,et al.  Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss. , 2005, Diabetes.

[6]  D. Sessler,et al.  Tissue Oxygenation in Obese and Non-obese Patients During Laparoscopy , 2005, Obesity surgery.

[7]  T. Standiford,et al.  Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. , 2005, American journal of respiratory and critical care medicine.

[8]  M. Matsuda,et al.  Visfatin: A Protein Secreted by Visceral Fat That Mimics the Effects of Insulin , 2005, Science.

[9]  Yihai Cao,et al.  Angiogenesis Inhibitor, TNP-470, Prevents Diet-Induced and Genetic Obesity in Mice , 2004, Circulation research.

[10]  J. Fleshman,et al.  Obesity Decreases Perioperative Tissue Oxygenation , 2004, Anesthesiology.

[11]  M. Lafontan,et al.  Effects of hypoxia on the expression of proangiogenic factors in differentiated 3T3-F442A adipocytes , 2003, International Journal of Obesity.

[12]  N. Tamaki,et al.  Dominant-negative hypoxia-inducible factor-1 alpha reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism. , 2003, The American journal of pathology.

[13]  B. Lowell,et al.  Adipose tissue mass can be regulated through the vasculature , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[14]  M. Matsuda,et al.  Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 , 2002, Nature Medicine.

[15]  P. Scherer,et al.  ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism , 2002, Trends in Endocrinology & Metabolism.

[16]  Y. Terauchi,et al.  The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity , 2001, Nature Medicine.

[17]  H. Esumi,et al.  Identification of Hypoxia-inducible Factor 1 Ancillary Sequence and Its Function in Vascular Endothelial Growth Factor Gene Induction by Hypoxia and Nitric Oxide* , 2001, The Journal of Biological Chemistry.

[18]  G. Semenza.  Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1. , 2000, The Journal of clinical investigation.

[19]  E. Pauwels,et al.  Positron emission tomography with 2-[18F]fluoro-2-deoxy-D-glucose in oncology , 2000, Journal of Cancer Research and Clinical Oncology.

[20]  J. Flier,et al.  Obesity and insulin resistance. , 2000, The Journal of clinical investigation.

[21]  A. Zeiher,et al.  Insulin-mediated stimulation of protein kinase Akt: A potent survival signaling cascade for endothelial cells. , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[22]  J. Arends,et al.  A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization , 1999, FEBS letters.

[23]  T. Funahashi,et al.  Molecular Mechanism of Metabolic Syndrome X: Contribution of Adipocytokines · Adipocyte‐derived Bioactive Substances , 1999, Annals of the New York Academy of Sciences.

[24]  N. Tamaki,et al.  Expression of glucose transporters in human pancreatic tumors compared with increased FDG accumulation in PET study. , 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[25]  M. Gassmann,et al.  Oxygen-regulated Transferrin Expression Is Mediated by Hypoxia-inducible Factor-1* , 1997, The Journal of Biological Chemistry.

[26]  Rakesh K. Jain,et al.  Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation , 1997, Nature Medicine.

[27]  G. Semenza,et al.  Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1* , 1996, The Journal of Biological Chemistry.

[28]  S. Yamashita,et al.  Enhanced expression of PAI–1 in visceral fat: Possible contributor to vascular disease in obeisty , 1996, Nature Medicine.

[29]  B. Ebert,et al.  Hypoxia and Mitochondrial Inhibitors Regulate Expression of Glucose Transporter-1 via Distinct Cis-acting Sequences (*) , 1995, The Journal of Biological Chemistry.

[30]  S. Kourembanas,et al.  Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer. , 1995, Circulation research.

[31]  G. Semenza,et al.  Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[32]  B. Spiegelman,et al.  Tumor Necrosis Factor α: A Key Component of the Obesity-Diabetes Link , 1994, Diabetes.

[33]  G. Semenza,et al.  Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. , 1994, The Journal of biological chemistry.

[34]  B. Ebert,et al.  Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[35]  I McNiece,et al.  Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor , 1994, Molecular and cellular biology.

[36]  G. Semenza,et al.  A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation , 1992, Molecular and cellular biology.

[37]  A. Francendese,et al.  Adipocyte blood flow is decreased in obese Zucker rats. , 1987, The American journal of physiology.

[38]  M. Digirolamo,et al.  Adipose tissue blood flow and cellularity in the growing rabbit. , 1975, The American journal of physiology.

[39]  J. Lloyd,et al.  Relation between Age of Onset of Obesity and Size and Number of Adipose Cells , 1972, British medical journal.

[40]  H. Hanley,et al.  Relationship of adipose tissue blood flow to fat cell size and number. , 1971, The American journal of physiology.

[41]  B. Spiegelman,et al.  Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. , 1993, Science.