Vascular Dysmorphogenesis Caused by an Activating Mutation in the Receptor Tyrosine Kinase TIE2

[1]  Pamela F. Jones,et al.  Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning , 1996, Cell.

[2]  Joseph Schlessinger,et al.  Structure of the FGF Receptor Tyrosine Kinase Domain Reveals a Novel Autoinhibitory Mechanism , 1996, Cell.

[3]  D. Donoghue,et al.  Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II , 1996, Molecular and cellular biology.

[4]  B. Sumpio,et al.  Matrix-specific effect of endothelial control of smooth muscle cell migration. , 1996, Journal of vascular surgery.

[5]  D. Ornitz,et al.  Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia , 1996, Nature Genetics.

[6]  D. W. Johnson,et al.  Mutations in the activin receptor–like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2 , 1996, Nature Genetics.

[7]  David J. Anderson,et al.  Alternative Neural Crest Cell Fates Are Instructively Promoted by TGFβ Superfamily Members , 1996, Cell.

[8]  J. Mulliken,et al.  E-selectin is present in proliferating endothelial cells in human hemangiomas. , 1996, The American journal of pathology.

[9]  A. Mccarthy Development , 1996, Current Opinion in Neurobiology.

[10]  M. Fillinger,et al.  Endothelial cell modulation of smooth muscle cell morphology and organizational growth pattern , 1996, Annals of vascular surgery.

[11]  R. Gorlin,et al.  A two-hit model for developmental defects in Gorlin syndrome , 1996, Nature Genetics.

[12]  M. Kirby,et al.  Neural crest and cardiovascular patterning. , 1995, Circulation research.

[13]  Thomas N. Sato,et al.  Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation , 1995, Nature.

[14]  M. Lovett,et al.  A single ataxia telangiectasia gene with a product similar to PI-3 kinase. , 1995, Science.

[15]  K. Alitalo,et al.  Vascularization of the mouse embryo: A study of flk‐1, tek, tie, and vascular endothelial growth factor expression during development , 1995, Developmental dynamics : an official publication of the American Association of Anatomists.

[16]  K. Alitalo,et al.  Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[17]  D. W. Johnson,et al.  A gene for familial venous malformations maps to chromosome 9p in a second large kindred. , 1995, Journal of medical genetics.

[18]  Charis Eng,et al.  Catalytic specificity of protein-tyrosine kinases is critical for selective signalling , 1995, Nature.

[19]  I. Kaitila,et al.  Achondroplasia is defined by recurrent G380R mutations of FGFR3. , 1995, American journal of human genetics.

[20]  L. Bonin,et al.  Vascular cell interactions modulate the expression of endothelin-1 and platelet-derived growth factor BB. , 1994, The American journal of physiology.

[21]  A. Duncan,et al.  Assignment of the endothelial-specific protein receptor tyrosine kinase gene (TEK) to human chromosome 9p21. , 1994, Genomics.

[22]  J. Seidman,et al.  Assignment of a locus for dominantly inherited venous malformations to chromosome 9p. , 1994, Human molecular genetics.

[23]  M. Gertsenstein,et al.  Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. , 1994, Genes & development.

[24]  Philippe Soriano,et al.  Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. , 1994, Genes & development.

[25]  B Swolin,et al.  Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities. , 1994, Genes & development.

[26]  J. Mulliken,et al.  Cellular markers that distinguish the phases of hemangioma during infancy and childhood. , 1994, The Journal of clinical investigation.

[27]  R. Sayers,et al.  Human venous endothelium can promote intimal hyperplasia in a paracrine manner. , 1994, Journal of vascular surgery.

[28]  E. Shinbrot,et al.  Expression of the platelet‐derived growth factor β receptor during organogenesis and tissue differentiation in the mouse embryo , 1994, Developmental dynamics : an official publication of the American Association of Anatomists.

[29]  D. W. Johnson,et al.  Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1 , 1994, Nature Genetics.

[30]  D. Ruiter,et al.  Characteristics and possible function of endoglin, a TGF-beta binding protein. , 1993, Behring Institute Mitteilungen.

[31]  A. Desmoulière,et al.  Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts , 1993, The Journal of cell biology.

[32]  M. Fillinger,et al.  The effect of endothelial cell coculture on smooth muscle cell proliferation. , 1993, Journal of vascular surgery.

[33]  Sandra R. Smith,et al.  Growth factor effects on cells of the vascular wall: a survey. , 1993, Growth factors.

[34]  K. Carraway,et al.  Biochemical comparisons of the normal and oncogenic forms of insect cell-expressed neu tyrosine kinases. , 1992, The Journal of biological chemistry.

[35]  R. Ohlsson,et al.  Angiogenesis during human extraembryonic development involves the spatiotemporal control of PDGF ligand and receptor gene expression. , 1991, Development.

[36]  W. Newman,et al.  Vascular cells respond differentially to transforming growth factors beta 1 and beta 2 in vitro. , 1991, The American journal of pathology.

[37]  N Nakayashiki,et al.  Sweat protein components tested by SDS-polyacrylamide gel electrophoresis followed by immunoblotting. , 1990, The Tohoku journal of experimental medicine.

[38]  C. Heldin,et al.  B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[39]  D. Noden Embryonic origins and assembly of blood vessels. , 1989, The American review of respiratory disease.

[40]  Sandra R. Smith,et al.  An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[41]  H. Nakamura,et al.  Electron microscopic study of the prenatal development of the thoracic aorta in the rat. , 1988, The American journal of anatomy.

[42]  T. Doetschman,et al.  Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies. , 1988, Development.

[43]  W. Risau,et al.  Changes in the vascular extracellular matrix during embryonic vasculogenesis and angiogenesis. , 1988, Developmental biology.

[44]  P A D'Amore,et al.  Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells , 1987, The Journal of cell biology.

[45]  P. Chomczyński,et al.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.

[46]  R. Ross,et al.  The biology of platelet-derived growth factor , 1986, Cell.

[47]  Gary R. Grotendorst,et al.  Platelet‐derived growth factor is a chemoattractant for vascular smooth muscle cells , 1982, Journal of cellular physiology.

[48]  Gary R. Grotendorst,et al.  Attachment of smooth muscle cells to collagen and their migration toward platelet-derived growth factor. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[49]  Henrt Sharp VASCULAR BIRTHMARKS , 1953, The Medical journal of Australia.