123I-ioflupane SPECT scan in a patient with Creutzfeldt-Jakob disease.
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A 62-year-old woman presented with gait ataxia, bradykinesia, bilateral rigidity, choreic and dystonic movements, and psychomotor slowing. Magnetic resonance imaging (MRI) (Fig. 1), EEG and CSF analysis were compatible with a diagnosis of Creutzfeldt-Jakob disease (CJD). The 123I-ioflupane SPECT (Fig. 2) was normal, indicating the relative sparing of nigro-striatal fibers and suggesting that her movement disorder was due to postsynaptic
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