Multimodality medical image registration by mutual information and Harris corner detector

A maximization of mutual information based multimodality medical image registration method is described.Due to the in- feriority ofimage registration using maximum mutual information,the registration based on comer points is researched.Harris operator isused.Despite ofits advantages over other algorithms,it will introduce artifacts in calculatingjoint histogram with conventional partial volume (PV) interpolation.The search strategy used the improved genetic algorithm to find the optimum value.Experimental results indicate the proposed algorithm can achieve better accuracy and robustness.