Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling.
暂无分享,去创建一个
R. Derynck | J. Bluestone | D. Sheppard | H. Chapman | Dan Du | Samantha L. Bailey-Bucktrout | Pinglong Xu | Y. Xi | A. Melton | Daqi Xu | Qian Zhang | Weiwen Xiang | Jianming Liu | Samantha Bailey-bucktrout
[1] K. Mossman,et al. Danger, diversity and priming in innate antiviral immunity. , 2014, Cytokine & growth factor reviews.
[2] C. Reis e Sousa,et al. Cytosolic Sensing of Viruses , 2013, Immunity.
[3] Samy Lamouille,et al. TGF-&bgr; signaling and epithelial–mesenchymal transition in cancer progression , 2013, Current opinion in oncology.
[4] R. Weinberg,et al. Cancer stem cells and epithelial-mesenchymal transition: concepts and molecular links. , 2012, Seminars in cancer biology.
[5] Daniel J. Kuster,et al. Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo , 2012, The Journal of experimental medicine.
[6] J. Massagué. TGFβ signalling in context , 2012, Nature Reviews Molecular Cell Biology.
[7] C. Heldin,et al. Regulation of EMT by TGFβ in cancer , 2012, FEBS letters.
[8] R. Derynck,et al. Post‐translational regulation of TGF‐β receptor and Smad signaling , 2012, FEBS letters.
[9] J. Turnay,et al. Histone deacetylase inhibitors upregulate MMP11 gene expression through Sp1/Smad complexes in human colon adenocarcinoma cells. , 2012, Biochimica et biophysica acta.
[10] J. Hiscott,et al. Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter. , 2011, Current opinion in immunology.
[11] T. Fujita,et al. RIG‐I‐like receptors: cytoplasmic sensors for non‐self RNA , 2011, Immunological reviews.
[12] S. Akira,et al. Recognition of nucleic acids by pattern‐recognition receptors and its relevance in autoimmunity , 2011, Immunological reviews.
[13] L. Lefrançois,et al. Regional and mucosal memory T cells , 2011, Nature Immunology.
[14] H. Chapman,et al. Epithelial-mesenchymal interactions in pulmonary fibrosis. , 2011, Annual review of physiology.
[15] Jerzy Adamski,et al. IKK&agr; controls canonical TGF&bgr;–SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in Panc1 cells , 2013, Journal of Cell Science.
[16] Kohei Miyazono,et al. TGFβ signalling: a complex web in cancer progression , 2010, Nature Reviews Cancer.
[17] Li Yang,et al. TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression. , 2010, Trends in immunology.
[18] J. C. McDermott,et al. Nuclear Function of Smad7 Promotes Myogenesis , 2009, Molecular and Cellular Biology.
[19] P. Cohen,et al. Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation. , 2009, The Journal of biological chemistry.
[20] M. A. Curotto de Lafaille,et al. Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor? , 2009, Immunity.
[21] Samy Lamouille,et al. TGF-β-induced epithelial to mesenchymal transition , 2009, Cell Research.
[22] H. Aburatani,et al. Chromatin Immunoprecipitation on Microarray Analysis of Smad2/3 Binding Sites Reveals Roles of ETS1 and TFAP2A in Transforming Growth Factor β Signaling , 2008, Molecular and Cellular Biology.
[23] R. Flavell,et al. TGF-β: A Master of All T Cell Trades , 2008, Cell.
[24] L. Chin,et al. Direct transcriptional activation of promyelocytic leukemia protein by IFN regulatory factor 3 induces the p53-dependent growth inhibition of cancer cells. , 2007, Cancer research.
[25] Samy Lamouille,et al. Cell size and invasion in TGF-β–induced epithelial to mesenchymal transition is regulated by activation of the mTOR pathway , 2007, The Journal of cell biology.
[26] M. Neurath,et al. In vitro generation of CD4+CD25+ regulatory cells from murine naive T cells , 2007, Nature Protocols.
[27] T. Curiel,et al. Tregs and rethinking cancer immunotherapy. , 2007, The Journal of clinical investigation.
[28] Feng Chen,et al. Smad7 Antagonizes Transforming Growth Factor β Signaling in the Nucleus by Interfering with Functional Smad-DNA Complex Formation , 2007, Molecular and Cellular Biology.
[29] C. Heldin,et al. Transforming growth factor-β employs HMGA2 to elicit epithelial–mesenchymal transition , 2006, The Journal of cell biology.
[30] C. Coban,et al. Essential role of IPS-1 in innate immune responses against RNA viruses , 2006, The Journal of experimental medicine.
[31] D. Sheppard,et al. Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis. , 2006, Proceedings of the American Thoracic Society.
[32] H. Weiner,et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells , 2006, Nature.
[33] T. Gelehrter,et al. Role of steroid receptor coactivators in glucocorticoid and transforming growth factor beta regulation of plasminogen activator inhibitor gene expression. , 2006, Molecular endocrinology.
[34] S. Akira,et al. Pathogen Recognition and Innate Immunity , 2006, Cell.
[35] Xiaoyu Hu,et al. The GRIP1:IRF3 interaction as a target for glucocorticoid receptor‐mediated immunosuppression , 2006, The EMBO journal.
[36] R. Derynck,et al. SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS , 2005 .
[37] Cheng Liu,et al. Crystal structure of IRF-3 in complex with CBP. , 2005, Structure.
[38] Mark P. de Caestecker,et al. Structural Basis of Heteromeric Smad Protein Assembly in TGF-β Signaling , 2004 .
[39] Li Li,et al. Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3 , 2003, The Journal of experimental medicine.
[40] S. Akira,et al. X-ray crystal structure of IRF-3 and its functional implications , 2003, Nature Structural Biology.
[41] R. Derynck,et al. Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation , 2003, Nature Structural Biology.
[42] Ying E. Zhang,et al. Smad-dependent and Smad-independent pathways in TGF-β family signalling , 2003, Nature.
[43] Guo-Ping Zhou,et al. Triggering the Interferon Antiviral Response Through an IKK-Related Pathway , 2003, Science.
[44] B. Olson,et al. Inhibition of Transforming Growth Factor (TGF)- 1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF- Type I Receptor Kinase Activity: SB-431542 , 2002 .
[45] Seong-Jin Kim,et al. The Androgen Receptor Represses Transforming Growth Factor-β Signaling through Interaction with Smad3* , 2002, The Journal of Biological Chemistry.
[46] E. Fraenkel,et al. A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies. , 2001, Molecular cell.
[47] J. Massagué,et al. TGFβ influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b , 2001, Nature Cell Biology.
[48] R. Derynck,et al. Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15Ink4B transcription in response to TGF‐β , 2000 .
[49] J. Massagué,et al. Inhibition of transforming growth factor-β/SMAD signalling by the interferon-γ/STAT pathway , 1999, Nature.
[50] D. Levy,et al. Differential viral induction of distinct interferon‐α genes by positive feedback through interferon regulatory factor‐7 , 1998, The EMBO journal.
[51] R. Derynck,et al. Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription , 1998, Nature.
[52] R. Derynck,et al. The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation. , 1998, Genes & development.
[53] T. Hunter,et al. TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300. , 1998, Genes & development.
[54] A. Moustakas,et al. Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[55] J. Hiscott,et al. Virus-Dependent Phosphorylation of the IRF-3 Transcription Factor Regulates Nuclear Translocation, Transactivation Potential, and Proteasome-Mediated Degradation , 1998, Molecular and Cellular Biology.
[56] N. Reich,et al. Interferon Regulatory Factor 3 and CREB-Binding Protein/p300 Are Subunits of Double-Stranded RNA-Activated Transcription Factor DRAF1 , 1998, Molecular and Cellular Biology.
[57] T. Maniatis,et al. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. , 1998, Molecular cell.
[58] C. Heldin,et al. Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling , 1997, Nature.
[59] K. Miyazono,et al. Smad6 inhibits signalling by the TGF-β superfamily , 1997, Nature.
[60] J. Wrana,et al. The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling , 1997, Cell.
[61] 洋英 大西,et al. 膵疾患におけるInterferon Regulatory Factorの役割 , 2014 .
[62] Ying E Zhang,et al. Non-Smad pathways in TGF-β signaling , 2009, Cell Research.
[63] T. Maniatis,et al. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. , 2003, Nature immunology.
[64] R. Derynck,et al. Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta. , 2000, The EMBO journal.
[65] C. Heldin,et al. Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling. , 1997, Nature.
[66] D Falb,et al. The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. , 1997, Cell.
[67] R. Derynck,et al. Transforming Growth Factor (cid:2) /Smad3 Signaling Regulates IRF-7 Function and Transcriptional Activation of the Beta Interferon Promoter , 2022 .