论文信息 - Sterols with Cyclopropane-Containing Side Chains: Synthesis and Acid Isomerization†

Sterols with Cyclopropane-Containing Side Chains: Synthesis and Acid Isomerization†

To test the eventual involvement of sterols with a cyclopropane containing side chain in bio-methylation processes, 24,25-methanocholest-5-en-3β-ol (5) and 24,25-methano-26-methylcholest-5-en-3β-ol (6) were synthesized. Together with the naturally occurring cyclopropane petrosterol (1), they were submitted to acid isomerization to provide chemical models for some of their potential metabolites.

C. Djerassi | M. Rohmer | C. Tarchini

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