Textbook of Receptor Pharmacology

Classical approaches to the study of drug-receptor interactions molecular structure of G-protein coupled receptors molecular structure of ligand-gated ion channel-receptors molecular structure of tyrosine kinase-linked receptors direct measurement of drug binding to receptors introduction to signal transduction receptors linked to ion channels - activation and block G-proteins phospholipases and phosphokinases - a source of lipid-derived second messengers intracellular calcium protein kinase C and diacylglycerol cyclic nucleotides signal transduction through protein tyrosine kinases receptors as pharmaceutical targets.