A perfused tissue phantom for ultrasound hyperthermia

In this investigation, the phantom, consisting of a fixed porcine kidney with thermocouples placed throughout the tissue, was perfused with degassed water by a variable flow rate pump. The phantom was insonated by an unfocused multielement ultrasound applicator, and the temperatures in the phantom were recorded. The results indicate that for testing protocols where tissue phantoms are needed, the fixed kidney preparation offers an opportunity to use a more realistic phantom than has previously been available to assess the heating performance of ultrasound hyperthermia applicators.<<ETX>>

[1]  Arthur W. Guy,et al.  Therapeutic applications of electromagnetic power , 1974 .

[2]  M Intaglietta,et al.  Tissue perfusion inhomogeneity during early tumor growth in rats. , 1979, Journal of the National Cancer Institute.

[3]  W. Swindell,et al.  Simulation of Focused, Scanned Ultrasonic Heating of Deep-Seated Tumors: The Effect of Blood Perfusion , 1984, IEEE Transactions on Sonics and Ultrasonics.

[4]  Cooper Te,et al.  Correlation of thermal properties of some human tissue with water content. , 1971 .

[5]  Wesley L. Nyborg,et al.  Heat generation by ultrasound in a relaxing medium , 1981 .

[6]  W Swindell,et al.  A scanned, focused, multiple transducer ultrasonic system for localized hyperthermia treatments. , 1987, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[7]  K R Foster,et al.  Perfused phantom models of microwave irradiated tissue. , 1986, Journal of biomechanical engineering.

[8]  R L Magin,et al.  A multi-element ultrasonic hyperthermia applicator with independent element control. , 1987, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[9]  M. M. Chen,et al.  Thermal conductivity and H2O content in rabbit kidney cortex and medulla , 1983 .

[10]  T E Cooper,et al.  Correlation of thermal properties of some human tissue with water content. , 1971, Aerospace medicine.

[11]  L. Frizzell,et al.  Determination of power deposition patterns for localized hyperthermia: a transient analysis. , 1988, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[12]  R. Jain,et al.  Tumor Blood Flow-Characterization, Modifications, and Role in Hyperthermia , 1984, IEEE Transactions on Sonics and Ultrasonics.

[13]  K. B. Ocheltree,et al.  Determination of power deposition patterns for localized hyperthermia: a steady-state analysis. , 1987, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[14]  L. Frizzell,et al.  Analysis of a multielement ultrasound hyperthermia applicator , 1989, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[15]  W. Fry,et al.  Determination of Absolute Sound Levels and Acoustic Absorption Coefficients by Thermocouple Probes—Theory , 1954 .