Investigação epidemiológica de Estomatite vesicular por achados clínicos em bovinos e equinos no

ABSTRACT.- Arruda R.C.N., Segundo J.M.F., Soares B.A., Martins N.R.S., Barcante T.A. & Bar-cante J.M.P. 2015. [ Stomatitis vesicular in cattle and horse in the Maranhao state. ] In-vestigacao epidemiologica de Estomatite vesicular por achados clinicos em bovinos e equi -nos no Estado do Maranhao. Pesquisa Veterinaria Brasileira 35(5):391-395. Laboratorio de Biologia Parasitaria, Setor de Medicina Veterinaria Preventiva, Departamento de Medici-na Veterinaria, Universidade Federal de Minas Gerais, Campus Universitario, Lavras, MG 37200-000, Brazil. E-mail: tbarcante@gmail.comVesicular stomatitis (VS) is an infectious viral disease that affects bovines, equines, swine, wild animals and humans. As it is indistinguishable from other vesicular diseases, mainly Foot and Mouth Disease (FMD), it causes restrictions in commercial livestock tra-de at national and international levels and also significant economic losses. As the epide-miology and maintenance of VS virus in nature are not clearly understood it is difficult to take effective control measures. VS was diagnosed in some regions of Brazil, such as Minas Gerais, Santa Catarina, Sao Paulo and Alagoas. Cattle and horses with clinical symptoms of drooling, shedding of the lingual epithelium, presence of vesicles on the oral mucosa were observed and reported to the National Animal Health Office health of Maranhao State, Brazil. Samples of serum of these animals were collected and sent to Laboratorio Nacional de Agropecuaria for ELISA and virus neutralization and differential diagnosis for Foot and Mouth Disease (FMD). The results of ELISA confirmed the VS. In the differential diagnosis, the results were negative for FMD. Samples of bovine epithelial tissue for VS by PCR confir-mation of diagnosis were collected and sent to Biological Institute of Sao Paulo. Molecular results confirmed the