Calculating a cure for cancer: managing medulloblastoma MATH1-ematically
暂无分享,去创建一个
[1] F. Zindy,et al. Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells. , 2010, Cancer research.
[2] S. Vandenberg,et al. Pleiotropic role for MYCN in medulloblastoma. , 2010, Genes & development.
[3] Lee F. Peng,et al. Small-molecule modulators of the Sonic Hedgehog signaling pathway. , 2010, Molecular bioSystems.
[4] P. Northcott,et al. Genomics of medulloblastoma: from Giemsa-banding to next-generation sequencing in 20 years. , 2010, Neurosurgical focus.
[5] Huda Y Zoghbi,et al. Deletion of Atoh1 Disrupts Sonic Hedgehog Signaling in the Developing Cerebellum and Prevents Medulloblastoma , 2009, Science.
[6] Richard Grundy,et al. The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors. , 2009, Cancer research.
[7] Dafydd G. Thomas,et al. Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo. , 2009, Developmental biology.
[8] Paul A. Northcott,et al. Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma , 2009, Nature Genetics.
[9] D. Ellison,et al. Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion. , 2008, Neoplasia.
[10] D. Kawauchi,et al. Transcriptional cascade from Math1 to Mbh1 and Mbh2 is required for cerebellar granule cell differentiation. , 2008, Developmental biology.
[11] Dirk Troost,et al. Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features , 2008, PloS one.
[12] Robert Machold,et al. Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells. , 2008, Cancer cell.
[13] C. Eberhart,et al. Medulloblastoma stem cells. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[14] S. Baylin,et al. Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma. , 2008, Genes & development.
[15] W. Weiss,et al. BMPs oppose Math1 in cerebellar development and in medulloblastoma. , 2008, Genes & development.
[16] F. Zindy,et al. Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development. , 2008, Genes & development.
[17] L. Rubin,et al. The hedgehog pathway and neurological disorders. , 2006, Annual review of neuroscience.
[18] T. Curran,et al. Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[19] G. Finocchiaro,et al. Expression of MATH1, a marker of cerebellar granule cell progenitors, identifies different medulloblastoma sub-types , 2004, Neuroscience Letters.
[20] Joel I. Pritchard,et al. The SmoA1 Mouse Model Reveals That Notch Signaling Is Critical for the Growth and Survival of Sonic Hedgehog-Induced Medulloblastomas , 2004, Cancer Research.
[21] Helen Baines,et al. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. , 2004, Cancer cell.
[22] M. Lohuizen,et al. Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas , 2004, Nature.
[23] V. Krizhanovsky,et al. Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway , 2004, Development.
[24] Heather L. Miller,et al. A molecular fingerprint for medulloblastoma. , 2003, Cancer research.
[25] Michael D. Cole,et al. Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors , 2003, Development.
[26] David Hogg,et al. Mutations in SUFU predispose to medulloblastoma , 2002, Nature Genetics.
[27] P. Cogen,et al. Hypermethylation of HIC-1 and 17p allelic loss in medulloblastoma. , 2002, Cancer research.
[28] V. Palma,et al. Hedgehog–GLI signaling and the growth of the brain , 2002, Nature Reviews Neuroscience.
[29] Jane E. Johnson,et al. Overexpression of MATH1 Disrupts the Coordination of Neural Differentiation in Cerebellum Development , 2001, Molecular and Cellular Neuroscience.
[30] V. Wallace. Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum , 1999, Current Biology.
[31] M. Scott,et al. Control of Neuronal Precursor Proliferation in the Cerebellum by Sonic Hedgehog , 1999, Neuron.
[32] H. Zoghbi,et al. Math1 is essential for genesis of cerebellar granule neurons , 1997, Nature.
[33] Anton Berns,et al. Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging , 1991, Cell.