Automated Diagnosis of Epilepsy Using Key-Point-Based Local Binary Pattern of EEG Signals

The electroencephalogram (EEG) signals are commonly used for diagnosis of epilepsy. In this paper, we present a new methodology for EEG-based automated diagnosis of epilepsy. Our method involves detection of key points at multiple scales in EEG signals using a pyramid of difference of Gaussian filtered signals. Local binary patterns (LBPs) are computed at these key points and the histogram of these patterns are considered as the feature set, which is fed to the support vector machine (SVM) for the classification of EEG signals. The proposed methodology has been investigated for the four well-known classification problems namely, 1) normal and epileptic seizure, 2) epileptic seizure and seizure free, 3) normal, epileptic seizure, and seizure free, and 4) epileptic seizure and nonseizure EEG signals using publically available university of Bonn EEG database. Our experimental results in terms of classification accuracies have been compared with existing methods for the classification of the aforementioned problems. Further, performance evaluation on another EEG dataset shows that our approach is effective for classification of seizure and seizure-free EEG signals. The proposed methodology based on the LBP computed at key points is simple and easy to implement for real-time epileptic seizure detection.

[1]  Hasan Ocak,et al.  Automatic detection of epileptic seizures in EEG using discrete wavelet transform and approximate entropy , 2009, Expert Syst. Appl..

[2]  Yi Chai,et al.  Classification of seizure based on the time-frequency image of EEG signals using HHT and SVM , 2014, Biomed. Signal Process. Control..

[3]  Clodoaldo Ap. M. Lima,et al.  Tackling EEG signal classification with least squares support vector machines: A sensitivity analysis study , 2010, Comput. Biol. Medicine.

[4]  Elif Derya Übeyli Least squares support vector machine employing model-based methods coefficients for analysis of EEG signals , 2010, Expert Syst. Appl..

[5]  Abdulhamit Subasi,et al.  EEG signal classification using PCA, ICA, LDA and support vector machines , 2010, Expert Syst. Appl..

[6]  Manoranjan Paul,et al.  Epileptic Seizure Prediction by Exploiting Spatiotemporal Relationship of EEG Signals Using Phase Correlation , 2016, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[7]  Daniel Rivero,et al.  Automatic epileptic seizure detection in EEGs based on line length feature and artificial neural networks , 2010, Journal of Neuroscience Methods.

[8]  Dimitrios I. Fotiadis,et al.  Epileptic Seizure Detection in EEGs Using Time–Frequency Analysis , 2009, IEEE Transactions on Information Technology in Biomedicine.

[9]  Matthijs C. Dorst Distinctive Image Features from Scale-Invariant Keypoints , 2011 .

[10]  K Lehnertz,et al.  Indications of nonlinear deterministic and finite-dimensional structures in time series of brain electrical activity: dependence on recording region and brain state. , 2001, Physical review. E, Statistical, nonlinear, and soft matter physics.

[11]  Ram Bilas Pachori,et al.  Classification of Seizure and Nonseizure EEG Signals Using Empirical Mode Decomposition , 2012, IEEE Transactions on Information Technology in Biomedicine.

[12]  Mahmut Ozer,et al.  EEG signals classification using the K-means clustering and a multilayer perceptron neural network model , 2011, Expert Syst. Appl..

[13]  Tamer Demiralp,et al.  Classification of electroencephalogram signals with combined time and frequency features , 2011, Expert Syst. Appl..

[14]  Elif Derya íbeyli Least squares support vector machine employing model-based methods coefficients for analysis of EEG signals , 2010 .

[15]  U. Rajendra Acharya,et al.  AUTOMATIC IDENTIFICATION OF EPILEPTIC EEG SIGNALS USING NONLINEAR PARAMETERS , 2009 .

[16]  U. Rajendra Acharya,et al.  Application of Higher Order Spectra to Identify Epileptic EEG , 2011, Journal of Medical Systems.

[17]  Duoqian Miao,et al.  Best basis-based wavelet packet entropy feature extraction and hierarchical EEG classification for epileptic detection , 2011, Expert Syst. Appl..

[18]  Osman Erogul,et al.  Epileptic EEG detection using the linear prediction error energy , 2010, Expert Syst. Appl..

[19]  U. Rajendra Acharya,et al.  Application of Recurrence Quantification Analysis for the Automated Identification of Epileptic EEG Signals , 2011, Int. J. Neural Syst..

[20]  Bijaya K. Panigrahi,et al.  Expert model for detection of epileptic activity in EEG signature , 2010, Expert Syst. Appl..

[21]  Marko Heikkilä,et al.  Description of interest regions with local binary patterns , 2009, Pattern Recognit..

[22]  U. Rajendra Acharya,et al.  Automatic Detection of Epileptic EEG Signals Using Higher Order cumulant Features , 2011, Int. J. Neural Syst..

[23]  Daniel Rivero,et al.  Epileptic seizure detection using multiwavelet transform based approximate entropy and artificial neural networks , 2010, Journal of Neuroscience Methods.

[24]  B. Matthews Comparison of the predicted and observed secondary structure of T4 phage lysozyme. , 1975, Biochimica et biophysica acta.

[25]  Ram Bilas Pachori,et al.  Epileptic seizure detection based on the instantaneous area of analytic intrinsic mode functions of EEG signals , 2013 .

[26]  V. Srinivasan,et al.  Approximate Entropy-Based Epileptic EEG Detection Using Artificial Neural Networks , 2007, IEEE Transactions on Information Technology in Biomedicine.

[27]  Moncef Gabbouj,et al.  Epileptic Seizure Classification of EEG Time-Series Using Rational Discrete Short-Time Fourier Transform , 2015, IEEE Transactions on Biomedical Engineering.

[28]  Ram Bilas Pachori,et al.  Epileptic seizure classification in EEG signals using second-order difference plot of intrinsic mode functions , 2014, Comput. Methods Programs Biomed..

[29]  U. Rajendra Acharya,et al.  Automated Diagnosis of epilepsy using CWT, HOS and Texture parameters , 2013, Int. J. Neural Syst..

[30]  Ian H. Witten,et al.  The WEKA data mining software: an update , 2009, SKDD.

[31]  Musa Peker,et al.  A Novel Method for Automated Diagnosis of Epilepsy Using Complex-Valued Classifiers , 2016, IEEE Journal of Biomedical and Health Informatics.

[32]  U. Rajendra Acharya,et al.  Automatic Identification of Epileptic and Background EEG Signals Using Frequency Domain Parameters , 2010, Int. J. Neural Syst..

[33]  Rajeev Sharma,et al.  Classification of Normal and Epileptic Seizure EEG Signals Based on Empirical Mode Decomposition , 2015, Complex System Modelling and Control Through Intelligent Soft Computations.

[34]  U. Rajendra Acharya,et al.  Application of Non-Linear and Wavelet Based Features for the Automated Identification of Epileptic EEG signals , 2012, Int. J. Neural Syst..

[35]  Ram Bilas Pachori,et al.  Classification of seizure and seizure-free EEG signals using local binary patterns , 2015, Biomed. Signal Process. Control..

[36]  U. Rajendra Acharya,et al.  Author's Personal Copy Biomedical Signal Processing and Control Automated Diagnosis of Epileptic Eeg Using Entropies , 2022 .

[37]  Guangyi Chen,et al.  Automatic EEG seizure detection using dual-tree complex wavelet-Fourier features , 2014, Expert Syst. Appl..

[38]  A. Tzallas,et al.  Automated Epileptic Seizure Detection Methods: A Review Study , 2012 .

[39]  Corinna Cortes,et al.  Support-Vector Networks , 1995, Machine Learning.

[40]  Ram Bilas Pachori,et al.  Classification of ictal and seizure-free EEG signals using fractional linear prediction , 2014, Biomed. Signal Process. Control..

[41]  Zhaohui Wu,et al.  Accelerometer-Based Gait Recognition by Sparse Representation of Signature Points With Clusters , 2015, IEEE Transactions on Cybernetics.

[42]  R. Uthayakumar,et al.  EPILEPTIC SEIZURE DETECTION IN EEG SIGNALS USING MULTIFRACTAL ANALYSIS AND WAVELET TRANSFORM , 2013 .

[43]  U. Rajendra Acharya,et al.  Use of principal component analysis for automatic classification of epileptic EEG activities in wavelet framework , 2012, Expert Syst. Appl..

[44]  Rajeev Sharma,et al.  Classification of epileptic seizures in EEG signals based on phase space representation of intrinsic mode functions , 2015, Expert Syst. Appl..

[45]  Daniel Rivero,et al.  Automatic feature extraction using genetic programming: An application to epileptic EEG classification , 2011, Expert Syst. Appl..

[46]  Hojjat Adeli,et al.  Principal Component Analysis-Enhanced Cosine Radial Basis Function Neural Network for Robust Epilepsy and Seizure Detection , 2008, IEEE Transactions on Biomedical Engineering.

[47]  Yilmaz Kaya,et al.  1D-local binary pattern based feature extraction for classification of epileptic EEG signals , 2014, Appl. Math. Comput..

[48]  Ram Bilas Pachori,et al.  Analysis of normal and epileptic seizure EEG signals using empirical mode decomposition , 2011, Comput. Methods Programs Biomed..

[49]  U. Rajendra Acharya,et al.  Automated EEG analysis of epilepsy: A review , 2013, Knowl. Based Syst..

[50]  Dimitrios I. Fotiadis,et al.  Automatic Seizure Detection Based on Time-Frequency Analysis and Artificial Neural Networks , 2007, Comput. Intell. Neurosci..