Factors associated with dietary supplement use among prescription medication users.

BACKGROUND We examined the patterns of nonvitamin dietary supplement (NVDS) use among adult prescription medication users in the United States. METHODS Using the 2002 National Health Interview Survey, we analyzed factors associated with NVDS use and prescription medication use in the prior 12 months with descriptive, chi(2), and logistic regression analysis. RESULTS In the United States, 21% of adult prescription medication users reported using NVDSs in the prior 12 months. Of the respondents who used both prescription medications and NVDSs in the prior 12 months, 69% did not discuss this use with a conventional medical practitioner. Among adults who used prescription medications in the prior 12 months, the most commonly used supplements included echinacea, ginseng, ginkgo, garlic, and glucosamine chondroitin. Prescription medication users with menopause and chronic gastrointestinal disorders had the highest rates of NVDS use (33% and 28%, respectively), and prescription medication users with coronary heart disease and history of myocardial infarction had the lowest rates of use (12% each). In the adjusted analysis, factors associated with increased use of NVDSs by prescription medication users included being female, being Hispanic, having more years of education, living in the West, lacking medical insurance, and having chronic conditions. Elderly respondents were less likely to use NVDSs. CONCLUSION One in 4 prescription medication users took an NVDS in the prior 12 months, yet the majority did not share this with a conventional medical professional.

[1]  T. Cheng Herbal interaction with warfarin. , 2005, Southern medical journal.

[2]  Steven Edward Kern,et al.  Interaction of St. John's Wort with oral contraceptives: effects on the pharmacokinetics of norethindrone and ethinyl estradiol, ovarian activity and breakthrough bleeding. , 2005, Contraception.

[3]  Jeffrey J Bruno,et al.  Herbal Use among US Elderly: 2002 National Health Interview Survey , 2005, The Annals of pharmacotherapy.

[4]  E. Williamson Interactions between herbal and conventional medicines , 2005, Expert opinion on drug safety.

[5]  A. Mitchell,et al.  Recent trends in use of herbal and other natural products. , 2005, Archives of internal medicine.

[6]  Dana Fennell Determinants of supplement usage. , 2004, Preventive medicine.

[7]  P. Barnes,et al.  Complementary and alternative medicine use among adults: United States, 2002. , 2004, Advance data.

[8]  C. Hershey,et al.  Use of complementary and alternative medicines by ambulatory patients. , 2004, Archives of internal medicine.

[9]  S. Gözüm,et al.  Use of herbal therapies by older, community-dwelling women. , 2004, Journal of advanced nursing.

[10]  P. Glassman,et al.  Incidence and severity of potential drug-dietary supplement interactions in primary care patients: an exploratory study of 2 outpatient practices. , 2004, Archives of internal medicine.

[11]  A. Izzo,et al.  Drug interactions with St. John's Wort (Hypericum perforatum): a review of the clinical evidence. , 2004, International journal of clinical pharmacology and therapeutics.

[12]  T. Tracy,et al.  Medication use in a rural gynecologic population: prescription, over-the-counter, and herbal medicines. , 2004, American journal of obstetrics and gynecology.

[13]  G. Mahady,et al.  Botanical dietary supplement use in peri- and postmenopausal women , 2003, Menopause.

[14]  Hanyu Ni,et al.  Utilization of Complementary and Alternative Medicine by United States Adults: Results From the 1999 National Health Interview Survey , 2002, Medical care.

[15]  J. Rivera,et al.  Evaluation of the Use of Complementary and Alternative Medicine in the Largest United States‐Mexico Border City , 2002, Pharmacotherapy.

[16]  A. Mitchell,et al.  Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey. , 2002, JAMA.

[17]  A. Fugh-Berman,et al.  Herb-drug interactions: review and assessment of report reliability. , 2001, British journal of clinical pharmacology.

[18]  J. Leung,et al.  The Prevalence and Predictors of the Use of Alternative Medicine in Presurgical Patients in Five California Hospitals , 2001, Anesthesia and analgesia.

[19]  E. Ernst Herb-drug interactions: potentially important but woefully under-researched , 2000, European Journal of Clinical Pharmacology.

[20]  P. McCabe New anti-epileptic drugs for the 21st century , 2000, Expert opinion on pharmacotherapy.

[21]  R. Kessler,et al.  Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. , 1998, JAMA.

[22]  Wei Duan,et al.  Herb-drug interactions: a literature review. , 2005, Drugs.

[23]  Stella M. Yu,et al.  Herbal supplement use among US women, 2000. , 2004, Journal of the American Medical Women's Association.

[24]  P. Barnes,et al.  Complementary and alternative medicine use among adults: United States, 2002. Advance data from vital and health statistics, no. 343 , 2004 .

[25]  M. Freedman,et al.  Potential Interactions between Herbal Medicines and Conventional Drug Therapies Used by Older Adults Attending a Memory Clinic , 2002, Drugs & aging.