A unifying hypothesis for PNMZL and PTFL: morphological variants with a common molecular profile

Key Points PNMZL has a molecular landscape characterized by low genomic complexity and frequent MAP2K1, TNFRSF14, and IRF8 alterations. The histologic and molecular features of PNMZL and PTFL suggest that they represent a morphologic spectrum of the same biologic entity.

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