Immunoreactive inhibin levels in peripheral blood during the breeding season in the female Japanese monkey.

Serum levels of immunoreactive inhibin as well as FSH, LH, estradiol-17 beta, and progesterone were measured by RIA in four mature female Japanese monkeys (Macaca fuscata fuscata) during the breeding season and subsequent transition into the nonbreeding season. During the breeding season, each monkey showed 2-6 ovulations, which were inferred from underlying endocrine events. The concentrations of serum inhibin increased during the luteal phase, but were low during the follicular phase. Such changes in serum inhibin levels correlated positively with those in serum progesterone levels. Basal levels of serum inhibin also increased during the breeding season, decreased during transition from the breeding season, and were low during the nonbreeding season. The parallel change in serum levels of inhibin and progesterone together with the increased basal levels of serum inhibin during this period suggests that both the CL and antral follicles are sources of circulating inhibin. Decreases in serum FSH levels during the luteal phase suggest that secretion of FSH is controlled by an inhibitory action of ovarian inhibin in addition to steroid hormones.

[1]  Y. Mori,et al.  Changes in plasma gonadotropins, ovarian steroids and inhibin concentrations in gilts following progesterone treatment with implantable osmotic pumps , 1989 .

[2]  K. Miyamoto,et al.  Radioimmunoassay of inhibin in various mammals. , 1989, The Journal of endocrinology.

[3]  H. Suginami,et al.  [Changes in plasma estradiol, progesterone and LH level in the menstrual cycle of the adult female Japanese monkey during the mating season]. , 1989, Jikken dobutsu. Experimental animals.

[4]  H. Burger,et al.  The importance of luteinizing hormone in the control of inhibin and progesterone secretion by the human corpus luteum. , 1989, The Journal of clinical endocrinology and metabolism.

[5]  G. Watanabe,et al.  Peripheral blood levels of immunoreactive inhibin during pseudopregnancy, pregnancy and lactation in the rat. , 1989, The Journal of endocrinology.

[6]  D. D. de Kretser,et al.  Cellular localization of inhibin mRNA in the bovine ovary by in-situ hybridization. , 1989, Journal of reproduction and fertility.

[7]  K. Miyamoto,et al.  Changes in serum concentrations of immunoreactive inhibin during the oestrous cycle of the rat. , 1989, The Journal of endocrinology.

[8]  H. Fraser,et al.  Immunoreactive inhibin concentrations in serum throughout the menstrual cycle of the macaque: suppression of inhibin during the luteal phase after treatment with an LHRH antagonist. , 1989, The Journal of endocrinology.

[9]  R. Rodgers,et al.  Inhibin mRNAs in ovine and bovine ovarian follicles and corpora lutea throughout the estrous cycle and gestation , 1989, Molecular and Cellular Endocrinology.

[10]  D. Baird,et al.  Changes in the plasma concentrations of inhibin throughout the normal sheep oestrous cycle and after the infusion of FSH. , 1989, The Journal of endocrinology.

[11]  P. Sawchenko,et al.  Rapid Changes in the Expression of Inhibin α-, βA-, and βB-Subunits in Ovarian Cell Types During the Rat Estrous Cycle , 1988 .

[12]  F. Kotsuji,et al.  Effects of inhibin from primate Sertoli cells on follicle-stimulating hormone and luteinizing hormone release by perifused rat pituitary cells. , 1988, Endocrinology.

[13]  H. Burger,et al.  Inhibin gene expression in the human corpus luteum. , 1987, The Journal of endocrinology.

[14]  H. Burger,et al.  Circulating immunoreactive inhibin levels during the normal human menstrual cycle. , 1987, The Journal of clinical endocrinology and metabolism.

[15]  Teresa K. Woodruff,et al.  Rat Inhibin: Molecular Cloning of α- and β-Subunit Complementary Deoxyribonucleic Acids and Expression in the Ovary , 1987 .

[16]  D. Baird,et al.  Production of inhibin bioactivity by human granulosa-lutein cells: stimulation by LH and testosterone in vitro. , 1987, The Journal of endocrinology.

[17]  J. Clements,et al.  Inhibin A-subunit gene expression in the ovaries of immature female rats is stimulated by pregnant mare serum gonadotrophin. , 1986, Biochemical and biophysical research communications.

[18]  K. Miyamoto,et al.  Demonstration of high molecular weight forms of inhibin in bovine follicular fluid (bFF) by using monoclonal antibodies to bFF 32K inhibin. , 1986, Biochemical and biophysical research communications.

[19]  M. Wilson,et al.  Endocrine control of the seasonal occurrence of ovulation in rhesus monkeys housed outdoors. , 1984, Endocrinology.

[20]  K. Oshima,et al.  Progesterone Levels in the Japanese Monkey (Macaca fuscata fuscata) during the Breeding and Nonbreeding Season and Pregnancy 1 , 1977, Journal of medical primatology.

[21]  T. Tominaga,et al.  Seasonal changes of plasma estradiol and progesterone in the Japanese monkey (Macaca fuscata fuscata). , 1977, Endocrinology.

[22]  G. Ross,et al.  A new radioimmunoassay for follicle-stimulating hormone in macaques: ovulatory menstrual cycles. , 1976, Endocrinology.