Ramipril retards development of aortic valve stenosis in a rabbit model: mechanistic considerations

Aortic valve stenosis (AVS) is associated with significant cardiovascular morbidity and mortality. To date, no therapeutic modality has been shown to be effective in retarding AVS progression. We evaluated the effect of angiotensin‐converting enzyme inhibition with ramipril on disease progression in a recently developed rabbit model of AVS.

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